Yan, Zhen

The role of ventral striatal cAMP signaling in stress-induced behaviors

Plattner, F., Hayashi, K., Hernández, A., Benavides, D. R., Tassin, T. C., Tan, C., Day, J., Fina, M. W., Yuen, E. Y., Yan, Z., et al. (2015) · Nature Neuroscience

Phosphodiesterase function and regulationNeurotransmitter Receptor Influence on Behavior

Cited by 94

Molecular determinants for the interaction between AMPA receptors and the clathrin adaptor complex AP-2

Kastning, K., Kukhtina, V., Kittler, J. T., Chen, G., Pechstein, A., Enders, S., Lee, S. H., Sheng, M., Yan, Z., & Haucke, V. (2007) · Proceedings of the National Academy of Sciences

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 88

Amelioration of autism-like social deficits by targeting histone methyltransferases EHMT1/2 in Shank3-deficient mice

Wang, Z.-J., Zhong, P., Ma, K., Seo, J.-S., Yang, F., Hu, Z., Zhang, F., Lin, L., Wang, J., Liu, T., et al. (2020) · Molecular Psychiatry

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 82

Dopamine D4Receptors Regulate AMPA Receptor Trafficking and Glutamatergic Transmission in GABAergic Interneurons of Prefrontal Cortex

Yuen, E. Y., & Yan, Z. (2009) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 81

Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilin

Liu, W., Yuen, E. Y., Allen, P. B., Feng, J., Greengard, P., & Yan, Z. (2006) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 79

The Stress Hormone Corticosterone Increases Synaptic α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors via Serum- and Glucocorticoid-inducible Kinase (SGK) Regulation of the GDI-Rab4 Complex

Liu, W., Yuen, E. Y., & Yan, Z. (2010) · Journal of Biological Chemistry

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 78

Behavioral, circuitry, and molecular aberrations by region-specific deficiency of the high-risk autism gene Cul3

Rapanelli, M., Tan, T., Wang, W., Wang, X., Wang, Z.-J., Zhong, P., Frick, L., Qin, L., Ma, K., Qu, J., et al. (2021) · Molecular Psychiatry

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 74

Chemogenetic Activation of Prefrontal Cortex Rescues Synaptic and Behavioral Deficits in a Mouse Model of 16p11.2 Deletion Syndrome

Wang, W., Rein, B., Zhang, F., Tan, T., Zhong, P., Qin, L., & Yan, Z. (2018) · The Journal of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 74

Histone deacetylase inhibitor MS-275 restores social and synaptic function in a Shank3-deficient mouse model of autism

Ma, K., Qin, L., Matas, E., Duffney, L. J., Liu, A., & Yan, Z. (2018) · Neuropsychopharmacology

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 71

Impaired Modulation of GABAergic Transmission by Muscarinic Receptors in a Mouse Transgenic Model of Alzheimer's Disease

Zhong, P., Gu, Z., Wang, X., Jiang, H., Feng, J., & Yan, Z. (2003) · Journal of Biological Chemistry

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 71

Reversal of synaptic and behavioral deficits in a 16p11.2 duplication mouse model via restoration of the GABA synapse regulator Npas4

Rein, B., Tan, T., Yang, F., Wang, W., Williams, J., Zhang, F., Mills, A., & Yan, Z. (2021) · Molecular Psychiatry

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 58

Histone Modification of Nedd4 Ubiquitin Ligase Controls the Loss of AMPA Receptors and Cognitive Impairment Induced by Repeated Stress

Wei, J., Xiong, Z., Lee, J. B., Cheng, J., Duffney, L. J., Matas, E., & Yan, Z. (2016) · The Journal of Neuroscience

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

Cited by 56

Muscarinic Potentiation of GABAAReceptor Currents Is Gated by Insulin Signaling in the Prefrontal Cortex

Ma, X.-H., Zhong, P., Gu, Z., Feng, J., & Yan, Z. (2003) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 56

Homeostatic regulation of glutamatergic transmission by dopamine D 4 receptors

Yuen, E. Y., Zhong, P., & Yan, Z. (2010) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 54

Histone deacetylase 6 gates the synaptic action of acute stress in prefrontal cortex

Lee, J. B., Wei, J., Liu, W., Cheng, J., Feng, J., & Yan, Z. (2012) · The Journal of Physiology

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

Cited by 52

Chemogenetic Activation of Prefrontal Cortex in Shank3-Deficient Mice Ameliorates Social Deficits, NMDAR Hypofunction, and Sgk2 Downregulation

Qin, L., Ma, K., & Yan, Z. (2019) · iScience

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 51

Muscarine Modulates Ca 2+ Channel Currents in Rat Sensorimotor Pyramidal Cells Via Two Distinct Pathways

Stewart, A. E., Yan, Z., Surmeier, D. J., & Foehring, R. C. (1999) · Journal of Neurophysiology

Ion channel regulation and functionNeuroscience and Neuropharmacology Research

Cited by 42

Bidirectional Regulation of Ca2+/Calmodulin-Dependent Protein Kinase II Activity by Dopamine D4 Receptors in Prefrontal Cortex

Gu, Z., & Yan, Z. (2004) · Molecular Pharmacology

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 41

The Novel Antipsychotic Drug Lurasidone Enhances N-Methyl-d-aspartate Receptor-Mediated Synaptic Responses

Yuen, E. Y., Li, X., Wei, J., Horiguchi, M., Meltzer, H. Y., & Yan, Z. (2012) · Molecular Pharmacology

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 38

Chronic antidepressant treatment alters serotonergic regulation of GABA transmission in prefrontal cortical pyramidal neurons

Zhong, P., & Yan, Z. (2004) · Neuroscience

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 37

Regulation of the NMDA receptor-mediated synaptic response by acetylcholinesterase inhibitors and its impairment in an animal model of Alzheimer's disease

Chen, G., Chen, P., Tan, H., Ma, D., Dou, F., Feng, J., & Yan, Z. (2008) · Neurobiology of Aging

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 36

Activation of Dopamine D4 Receptors Induces Synaptic Translocation of Ca2+/Calmodulin-Dependent Protein Kinase II in Cultured Prefrontal Cortical Neurons

Gu, Z., Jiang, Q., Yuen, E. Y., & Yan, Z. (2006) · Molecular Pharmacology

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 35

Dopamine Differentially Regulates Response Dynamics of Prefrontal Cortical Principal Neurons and Interneurons to Optogenetic Stimulation of Inputs from Ventral Tegmental Area

Zhong, P., Qin, L., & Yan, Z. (2020) · Cerebral Cortex

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 34

RACK1 is involved in β-amyloid impairment of muscarinic regulation of GABAergic transmission

Liu, W., Dou, F., Feng, J., & Yan, Z. (2011) · Neurobiology of Aging

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 33