Taipale, Mikko

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

Taipale, M., Jarosz, D. F., & Lindquist, S. (2010) · Nature Reviews Molecular Cell Biology

Heat shock proteins researchUbiquitin and proteasome pathways

Cited by 1,818

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

Taipale, M., Krykbaeva, I., Koeva, M., Kayatekin, C., Westover, K. D., Karras, G. I., & Lindquist, S. (2012) · Cell

Heat shock proteins researchUbiquitin and proteasome pathways

Cited by 879

Widespread macromolecular interaction perturbations in human genetic disorders

Sahni, N., Yi, S., Taipale, M., Fuxman Bass, J. I., Coulombe-Huntington, J., Yang, F., Peng, J., Weile, J., Karras, G. I., Wang, Y., et al. (2015) · Cell

Genomics and Rare DiseasesBioinformatics and Genomic Networks

Cited by 594

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

Wei, G., Badis, G., Berger, M. F., Kivioja, T., Palin, K., Enge, M., Bonke, M., Jolma, A., Varjosalo, M., Gehrke, A. R., et al. (2010) · The EMBO Journal

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 568

Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities

Jolma, A., Kivioja, T., Toivonen, J., Cheng, L., Wei, G., Enge, M., Taipale, M., Vaquerizas, J. M., Yan, J., Sillanpää, M. J., et al. (2010) · Genome Research

Genomics and Chromatin DynamicsAdvanced biosensing and bioanalysis techniques

Cited by 441

Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition

Lambert, J.-P., Ivosev, G., Couzens, A. L., Larsen, B., Taipale, M., Lin, Z.-Y., Zhong, Q., Lindquist, S., Vidal, M., Aebersold, R., et al. (2013) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 318

Protein Homeostasis and the Phenotypic Manifestation of Genetic Diversity: Principles and Mechanisms

Jarosz, D. F., Taipale, M., & Lindquist, S. (2010) · Annual Review of Genetics

Evolution and Genetic DynamicsHeat shock proteins research

Cited by 179

Identification and functional characterization of transcriptional activators in human cells

Alerasool, N., Leng, H., Lin, Z.-Y., Gingras, A.-C., & Taipale, M. (2022) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 120

Genome-wide prediction and validation of peptides that bind human prosurvival Bcl-2 proteins

DeBartolo, J., Taipale, M., & Keating, A. E. (2014) · PLoS Computational Biology

Cell death mechanisms and regulationComputational Drug Discovery Methods

Cited by 39

Efficient, specific, and combinatorial control of endogenous exon splicing with dCasRx-RBM25

Li, J. D., Taipale, M., & Blencowe, B. J. (2024) · Molecular Cell

RNA Research and SplicingCRISPR and Genetic Engineering

Cited by 31