Smith, Hamilton O.

The sequence of the human genome

Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science

Genomics and Phylogenetic StudiesGenomic variations and chromosomal abnormalities

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Environmental genome shotgun sequencing of the sargasso sea

Venter, J. C., Remington, K., Heidelberg, J. F., Halpern, A. L., Rusch, D., Eisen, J. A., Wu, D., Paulsen, I., Nelson, K. E., Nelson, W., et al. (2004) · Science

Microbial Community Ecology and PhysiologyGenomics and Phylogenetic Studies

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The complete genome sequence of the gastric pathogen Helicobacter pylori

Tomb, J.-F., White, O., Kerlavage, A. R., Clayton, R. A., Sutton, G. G., Fleischmann, R. D., Ketchum, K. A., Klenk, H. P., Gill, S., Dougherty, B. A., et al. (1997) · Nature

Helicobacter pylori-related gastroenterology studiesBacterial Genetics and Biotechnology

Cited by 3,529

Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

Gibson, D. G., Glass, J. I., Lartigue, C., Noskov, V. N., Chuang, R.-Y., Algire, M. A., Benders, G. A., Montague, M. G., Ma, L., Moodie, M. M., et al. (2010) · Science

Microbial Metabolic Engineering and BioproductionRNA and protein synthesis mechanisms

Cited by 2,638

The Minimal Gene Complement of Mycoplasma genitalium

Fraser, C. M., Gocayne, J. D., White, O., Adams, M. D., Clayton, R. A., Fleischmann, R. D., Bult, C. J., Kerlavage, A. R., Sutton, G., Kelley, J. M., et al. (1995) · Science

Microbial infections and disease researchGenomics and Phylogenetic Studies

Cited by 2,545

Design and synthesis of a minimal bacterial genome

Hutchison, C. A., Chuang, R.-Y., Noskov, V. N., Assad-Garcia, N., Deerinck, T. J., Ellisman, M. H., Gill, J., Kannan, K., Karas, B. J., Ma, L., et al. (2016) · Science

Microbial Metabolic Engineering and BioproductionRNA and protein synthesis mechanisms

Cited by 1,500

Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome

Gibson, D. G., Benders, G. A., Andrews-Pfannkoch, C., Denisova, E. A., Baden-Tillson, H., Zaveri, J., Stockwell, T. B., Brownley, A., Thomas, D. W., Algire, M. A., et al. (2008) · Science

CRISPR and Genetic EngineeringMicrobial infections and disease research

Cited by 1,243

Essential genes of a minimal bacterium

Glass, J. I., Assad-Garcia, N., Alperovich, N., Yooseph, S., Lewis, M. R., Maruf, M., Hutchison, C. A., Smith, H. O., & Venter, J. C. (2006) · Proceedings of the National Academy of Sciences

Bacterial Genetics and BiotechnologyMicrobial infections and disease research

Cited by 912

Creating Bacterial Strains from Genomes That Have Been Cloned and Engineered in Yeast

Lartigue, C., Vashee, S., Algire, M. A., Chuang, R.-Y., Benders, G. A., Ma, L., Noskov, V. N., Denisova, E. A., Gibson, D. G., Assad-Garcia, N., et al. (2009) · Science

CRISPR and Genetic EngineeringMicrobial Metabolic Engineering and Bioproduction

Cited by 332

Essential metabolism for a minimal cell

Breuer, M., Earnest, E. E., Merryman, C., Wise, K. S., Sun, L., Lynott, M. R., Hutchison, C. A., Smith, H. O., Lapek, J. D., Gonzalez, D. J., et al. (2019) · eLife

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 190

Fundamental behaviors emerge from simulations of a living minimal cell

Thornburg, Z. R., Bianchi, D. M., Brier, T. A., Gilbert, B. R., Earnest, E. E., Melo, M. C. R., Safronova, N., Sáenz, J. P., Cook, A. T., Wise, K. S., et al. (2022) · Cell

Lipid Membrane Structure and BehaviorLipid metabolism and biosynthesis

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Kinetic modeling of the genetic information processes in a minimal cell

Thornburg, Z. R., Melo, M. C. R., Bianchi, D., Brier, T. A., Crotty, C., Breuer, M., Smith, H. O., Hutchison, C. A., Glass, J. I., & Luthey-Schulten, Z. (2019) · Frontiers in Molecular Biosciences

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

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