Bossé, Yohan

Bicuspid Aortic Valve: Identifying Knowledge Gaps and Rising to the Challenge From the International Bicuspid Aortic Valve Consortium (BAVCon)

Michelena, H. I., Prakash, S. K., Della Corte, A., Bissell, M. M., Anavekar, N., Mathieu, P., Bossé, Y., Limongelli, G., Bossone, E., Benson, D. W., et al. (2014) · Circulation

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 442

Oxidized Phospholipids, Lipoprotein(a), and Progression of Calcific Aortic Valve Stenosis

Capoulade, R., Chan, K. L., Yeang, C., Mathieu, P., Bossé, Y., Dumesnil, J. G., Tam, J. W., Teo, K. K., Mahmut, A., Yang, X., et al. (2015) · Journal of the American College of Cardiology

Cardiac Valve Diseases and TreatmentsAtherosclerosis and Cardiovascular Diseases

Cited by 417

Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis

Allen, R. J., Guillen-Guio, B., Oldham, J. M., Ma, S.-F., Dressen, A., Paynton, M. L., Kraven, L. M., Obeidat, M., Li, X., Ng, M., et al. (2020) · American Journal of Respiratory and Critical Care Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisGenetic Associations and Epidemiology

Cited by 329

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study

Allen, R. J., Porte, J., Braybrooke, R., Flores, C., Fingerlin, T. E., Oldham, J. M., Guillen-Guio, B., Ma, S.-F., Okamoto, T., John, A. E., et al. (2017) · The Lancet Respiratory Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisGenetic Associations and Epidemiology

Cited by 297

Sex-Related Discordance Between Aortic Valve Calcification and Hemodynamic Severity of Aortic Stenosis: Is Valvular Fibrosis the Explanation?

Simard, L., Côté, N., Dagenais, F., Mathieu, P., Couture, C., Trahan, S., Bossé, Y., Mohammadi, S., Pagé, S., Joubert, P., et al. (2017) · Circulation Research

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 294

P2Y2 receptor represses IL-6 expression by valve interstitial cells through Akt: implication for calcific aortic valve disease

El Husseini, D., Boulanger, M.-C., Mahmut, A., Bouchareb, R., Laflamme, M.-H., Fournier, D., Pibarot, P., Bossé, Y., & Mathieu, P. (2014) · Journal of Molecular and Cellular Cardiology

Cardiac Valve Diseases and TreatmentsAdenosine and Purinergic Signaling

Cited by 150

A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis

Thériault, S., Gaudreault, N., Lamontagne, M., Rosa, M., Boulanger, M.-C., Messika-Zeitoun, D., Clavel, M.-A., Capoulade, R., Dagenais, F., Pibarot, P., et al. (2018) · Nature Communications

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 135

Age, Sex, and Valve Phenotype Differences in Fibro‐Calcific Remodeling of Calcified Aortic Valve

Voisine, M., Hervault, M., Shen, M., Boilard, A., Filion, B., Rosa, M., Bossé, Y., Mathieu, P., Côté, N., & Clavel, M. (2020) · Journal of the American Heart Association

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 124

Systolic hypertension and progression of aortic valve calcification in patients with aortic stenosis: results from the PROGRESSA study

Tastet, L., Capoulade, R., Clavel, M.-A., Larose, É., Shen, M., Dahou, A., Arsenault, M., Mathieu, P., Bédard, É., Dumesnil, J. G., et al. (2017) · European Heart Journal – Cardiovascular Imaging

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 100

ATP acts as a survival signal and prevents the mineralization of aortic valve

Côté, N., El Husseini, D., Pépin, A., Guauque-Olarte, S., Ducharme, V., Bouchard-Cannon, P., Audet, A., Fournier, D., Gaudreault, N., Derbali, H., et al. (2012) · Journal of Molecular and Cellular Cardiology

Adenosine and Purinergic SignalingCardiac Valve Diseases and Treatments

Cited by 95

Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis

Perrot, N., Valerio, V., Moschetta, D., Boekholdt, S. M., Dina, C., Chen, H. Y., Abner, E., Martinsson, A., Manikpurage, H. D., Rigade, S., et al. (2020) · JACC: Basic to Translational Science

Cardiac Valve Diseases and TreatmentsDermatological and Skeletal Disorders

Cited by 91

Genetic Association Analyses Highlight IL6 , ALPL , and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis

Thériault, S., Dina, C., Messika-Zeitoun, D., Le Scouarnec, S., Capoulade, R., Gaudreault, N., Rigade, S., Li, Z., Simonet, F., Lamontagne, M., et al. (2019) · Circulation: Genomic and Precision Medicine

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 90

Genomics

Bossé, Y., Mathieu, P., & Pibarot, P. (2008) · Journal of the American College of Cardiology

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 82

RNA expression profile of calcified bicuspid, tricuspid, and normal human aortic valves by RNA sequencing

Guauque-Olarte, S., Droit, A., Tremblay-Marchand, J., Gaudreault, N., Kalavrouziotis, D., Dagenais, F., Seidman, J. G., Body, S. C., Pibarot, P., Mathieu, P., et al. (2016) · Physiological Genomics

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 82

The pathology and pathobiology of bicuspid aortic valve: State of the art and novel research perspectives

Mathieu, P., Bossé, Y., Huggins, G. S., Corte, A. D., Pibarot, P., Michelena, H. I., Limongelli, G., Boulanger, M., Evangelista, A., Bédard, E., et al. (2015) · The Journal of Pathology: Clinical Research

Aortic Disease and Treatment ApproachesCardiac Valve Diseases and Treatments

Cited by 76

Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated With Calcific Aortic Valve Disease

Guauque-Olarte, S., Messika-Zeitoun, D., Droit, A., Lamontagne, M., Tremblay-Marchand, J., Lavoie-Charland, E., Gaudreault, N., Arsenault, B. J., Dubé, M.-P., Tardif, J.-C., et al. (2015) · Circulation: Cardiovascular Genetics

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 72

Increased Biglycan in Aortic Valve Stenosis Leads to the Overexpression of Phospholipid Transfer Protein via Toll-Like Receptor 2

Derbali, H., Bossé, Y., Côté, N., Pibarot, P., Audet, A., Pépin, A., Arsenault, B., Couture, C., Després, J.-P., & Mathieu, P. (2010) · The American Journal of Pathology

Cardiac Valve Diseases and TreatmentsProteoglycans and glycosaminoglycans research

Cited by 71

Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis

Chen, H. Y., Cairns, B. J., Small, A. M., Burr, H. A., Ambikkumar, A., Martinsson, A., Thériault, S., Munter, H. M., Steffen, B., Zhang, R., et al. (2020) · JAMA Cardiology

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 65

Impact of Plasma Lp-PLA2 Activity on the Progression of Aortic Stenosis

Capoulade, R., Mahmut, A., Tastet, L., Arsenault, M., Bédard, É., Dumesnil, J. G., Després, J.-P., Larose, É., Arsenault, B. J., Bossé, Y., et al. (2015) · JACC: Cardiovascular Imaging

Cardiac Valve Diseases and TreatmentsLipoproteins and Cardiovascular Health

Cited by 61

Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation

Thériault, S., Li, Z., Abner, E., Luan, J., Manikpurage, H. D., Houessou, U., Zamani, P., Briend, M., Estonian Biobank Research Team, Boudreau, D. K., et al. (2024) · Nature Communications

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 49

Carbonic anhydrase XII in valve interstitial cells promotes the regression of calcific aortic valve stenosis

Bouchareb, R., Côté, N., Marie-Chloé-Boulanger, Le Quang, K., El Husseini, D., Asselin, J., Hadji, F., Lachance, D., Shayhidin, E. E., Mahmut, A., et al. (2015) · Journal of Molecular and Cellular Cardiology

Cardiac Valve Diseases and TreatmentsEnzyme function and inhibition

Cited by 25

Phenome-wide analyses establish a specific association between aortic valve PALMD expression and calcific aortic valve stenosis

Li, Z., Gaudreault, N., Arsenault, B. J., Mathieu, P., Bossé, Y., & Thériault, S. (2020) · Communications Biology

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 23

Enhancer-associated aortic valve stenosis risk locus 1p21.2 alters NFATC2 binding site and promotes fibrogenesis

Chignon, A., Rosa, M., Boulanger, M.-C., Argaud, D., Devillers, R., Bon-Baret, V., Mkannez, G., Li, Z., Rufiange, A., Gaudreault, N., et al. (2021) · iScience

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 18

Transcriptomic signatures of calcific aortic valve stenosis severity in human tricuspid and bicuspid aortic valves

Houessou, U., Zamani, P., Manikpurage, H. D., Li, Z., Gaudreault, N., Dahmene, M., Dagenais, F., Couture, C., Clavel, M.-A., Pibarot, P., et al. (2025) · JACC: Basic to Translational Science

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 11