Uchiyama, Yasuo

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Loss of autophagy in the central nervous system causes neurodegeneration in mice

Komatsu, M., Waguri, S., Chiba, T., Murata, S., Iwata, J.-I., Tanida, I., Ueno, T., Koike, M., Uchiyama, Y., Kominami, E., et al. (2006) · Nature

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 3,500

Impairment of starvation-induced and constitutive autophagy in Atg7 -deficient mice

Komatsu, M., Waguri, S., Ueno, T., Iwata, J., Murata, S., Tanida, I., Ezaki, J., Mizushima, N., Ohsumi, Y., Uchiyama, Y., et al. (2005) · The Journal of Cell Biology

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 2,331

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Klionsky, D. J., Abeliovich, H., Agostinis, P., Agrawal, D. K., Aliev, G., Askew, D. S., Baba, M., Baehrecke, E. H., Bahr, B. A., Ballabio, A., et al. (2008) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 2,230

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.

Komatsu, M., Waguri, S., Koike, M., Sou, Y.-S., Ueno, T., Hara, T., Mizushima, N., Iwata, J.-I., Ezaki, J., Murata, S., et al. (2007) · Cell

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 2,124

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

Lee, J.-H., Yu, W. H., Kumar, A., Lee, S., Mohan, P. S., Peterhoff, C. M., Wolfe, D. M., Martinez-Vicente, M., Massey, A. C., Sovak, G., et al. (2010) · Cell

Autophagy in Disease and TherapyAlzheimer's disease research and treatments

Cited by 1,212

Identification of Tim4 as a phosphatidylserine receptor

Miyanishi, M., Tada, K., Koike, M., Uchiyama, Y., Kitamura, T., & Nagata, S. (2007) · Nature

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 1,180

Autoimmune Disease and Impaired Uptake of Apoptotic Cells in MFG-E8-Deficient Mice

Hanayama, R., Tanaka, M., Miyasaka, K., Aozasa, K., Koike, M., Uchiyama, Y., & Nagata, S. (2004) · Science

Phagocytosis and Immune RegulationSystemic Lupus Erythematosus Research

Cited by 992

Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease

Yu, W. H., Cuervo, A. M., Kumar, A., Peterhoff, C. M., Schmidt, S. D., Lee, J.-H., Mohan, P. S., Mercken, M., Farmery, M. R., Tjernberg, L. O., et al. (2005) · The Journal of Cell Biology

Alzheimer's disease research and treatmentsAutophagy in Disease and Therapy

Cited by 967

Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury

Koike, M., Shibata, M., Tadakoshi, M., Gotoh, K., Komatsu, M., Waguri, S., Kawahara, N., Kuida, K., Nagata, S., Kominami, E., et al. (2008) · The American Journal of Pathology

Neonatal and fetal brain pathologyAutophagy in Disease and Therapy

Cited by 486

Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells

Yoshida, H., Kawane, K., Koike, M., Mori, Y., Uchiyama, Y., & Nagata, S. (2005) · Nature

Phagocytosis and Immune RegulationErythrocyte Function and Pathophysiology

Cited by 346

The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK–ERK pathway to late endosomes

Nada, S., Hondo, A., Kasai, A., Koike, M., Saito, K., Uchiyama, Y., & Okada, M. (2009) · The EMBO Journal

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 341

Participation of Autophagy in Storage of Lysosomes in Neurons from Mouse Models of Neuronal Ceroid-Lipofuscinoses (Batten Disease)

Koike, M., Shibata, M., Waguri, S., Yoshimura, K., Tanida, I., Kominami, E., Gotow, T., Peters, C., von Figura, K., Mizushima, N., et al. (2005) · The American Journal of Pathology

Lysosomal Storage Disorders ResearchAutophagy in Disease and Therapy

Cited by 330

Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for β-amyloid peptide over-production and localization in Alzheimer’s disease

Yu, W. H., Kumar, A., Peterhoff, C., Shapiro Kulnane, L., Uchiyama, Y., Lamb, B. T., Cuervo, A. M., & Nixon, R. A. (2004) · The International Journal of Biochemistry & Cell Biology

Alzheimer's disease research and treatmentsAutophagy in Disease and Therapy

Cited by 279

Autophagic Cell Death and Its Execution by Lysosomal Cathepsins.

UCHIYAMA, Y. (2001) · Archives of Histology and Cytology

Autophagy in Disease and TherapyCell death mechanisms and regulation

Cited by 243

Development of the circadian oscillator during differentiation of mouse embryonic stem cells in vitro

Yagita, K., Horie, K., Koinuma, S., Nakamura, W., Yamanaka, I., Urasaki, A., Shigeyoshi, Y., Kawakami, K., Shimada, S., Takeda, J., et al. (2010) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninPluripotent Stem Cells Research

Cited by 241

New Neurons Clear the Path of Astrocytic Processes for Their Rapid Migration in the Adult Brain

Kaneko, N., Marín, O., Koike, M., Hirota, Y., Uchiyama, Y., Wu, J. Y., Lu, Q., Tessier-Lavigne, M., Alvarez-Buylla, A., Okano, H., et al. (2010) · Neuron

Neurogenesis and neuroplasticity mechanismsAxon Guidance and Neuronal Signaling

Cited by 212

Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis.

Tashiro, Y., Urushitani, M., Inoue, H., Koike, M., Uchiyama, Y., Komatsu, M., Tanaka, K., Yamazaki, M., Abe, M., Misawa, H., et al. (2012) · Journal of Biological Chemistry

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 194

Human IAPP–induced pancreatic β cell toxicity and its regulation by autophagy

Shigihara, N., Fukunaka, A., Hara, A., Komiya, K., Honda, A., Uchida, T., Abe, H., Toyofuku, Y., Tamaki, M., Ogihara, T., et al. (2014) · Journal of Clinical Investigation

Pancreatic function and diabetesAutophagy in Disease and Therapy

Cited by 177

Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury

Xie, C., Ginet, V., Sun, Y., Koike, M., Zhou, K., Li, T., Li, H., Li, Q., Wang, X., Uchiyama, Y., et al. (2016) · Autophagy

Neonatal and fetal brain pathologyAutophagy in Disease and Therapy

Cited by 160

Free radical-independent protection by nerve growth factor and Bcl-2 of PC12 cells from hydrogen peroxide-triggered apoptosis

Satoh, T., Sakai, N., Enokido, Y., Uchiyama, Y., & Hatanaka, H. (1996) · Journal of Biochemistry

Cell death mechanisms and regulationRedox biology and oxidative stress

Cited by 146

Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice

Sato, S., Uchihara, T., Fukuda, T., Noda, S., Kondo, H., Saiki, S., Komatsu, M., Uchiyama, Y., Tanaka, K., & Hattori, N. (2018) · Scientific Reports

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 125

Variants in saposin D domain of prosaposin gene linked to Parkinson’s disease

Oji, Y., Hatano, T., Ueno, S.-I., Funayama, M., Ishikawa, K.-I., Okuzumi, A., Noda, S., Sato, S., Satake, W., Toda, T., et al. (2020) · Brain

Parkinson's Disease Mechanisms and TreatmentsLysosomal Storage Disorders Research

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