Free radical-independent protection by nerve growth factor and Bcl-2 of PC12 cells from hydrogen peroxide-triggered apoptosis

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

Wyllie, A. H. (1980) · Nature · doi:10.1038/284555a0 · Cited by 4,549 · see citing works

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1.

Schreck, R., RIEBER, P., & Baeuerle, P. A. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07761.x · Cited by 3,816 · see citing works

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

Hockenbery, D. M., Oltvai, Z. N., Yin, X., Milliman, C. L., & Korsmeyer, S. J. (1993) · Cell · doi:10.1016/0092-8674(93)80066-n · Cited by 3,420 · see citing works

Cell death during development of the nervous system

Oppenheim, R. W. (1991) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.14.030191.002321 · Cited by 3,084 · see citing works

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

Ji, Y. (1993) · Cell · doi:10.1016/0092-8674(93)90485-9 · Cited by 2,497 · see citing works

Genetic control of programmed cell death in the nematode C. elegans

Ellis, H. (1986) · Cell · doi:10.1016/0092-8674(86)90004-8 · Cited by 1,828 · see citing works

Developmental cell death: morphological diversity and multiple mechanisms

Clarke, P. H. (1990) · Anatomy and Embryology · doi:10.1007/bf00174615 · Cited by 1,695 · see citing works

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

Kane, D. J., Sarafian, T. A., Anton, R., Hahn, H., Gralla, E. B., Valentine, J. S., Örd, T., & Bredesen, D. E. (1993) · Science · doi:10.1126/science.8235659 · Cited by 1,671 · see citing works

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

Abate, C., Patel, L., Rauscher, F. J., & Curran, T. (1990) · Science · doi:10.1126/science.2118682 · Cited by 1,573 · see citing works

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2

Hengartner, M. O., & Horvitz, H. R. (1994) · Cell · doi:10.1016/0092-8674(94)90506-1 · Cited by 1,167 · see citing works

THE NERVE GROWTH FACTOR: PURIFICATION AS A 30,000-MOLECULAR-WEIGHT PROTEIN

Bocchini, V., & Angeletti, P. U. (1969) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.64.2.787 · Cited by 910 · see citing works

Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

Reynolds, I., & Hastings, T. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03318.1995 · Cited by 777 · see citing works

Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death

Greenlund, L. J. S., Deckwerth, T. L., & Johnson, E. M. (1995) · Neuron · doi:10.1016/0896-6273(95)90287-2 · Cited by 738 · see citing works

Programmed cell death and Bcl-2 protection in very low oxygen

Jacobson, M. D., & RAFF, M. C. (1995) · Nature · doi:10.1038/374814a0 · Cited by 625 · see citing works

bcl-2 inhibits death of central neural cells induced by multiple agents.

Zhong, L. T., Sarafian, T. A., Kane, D. J., Charles, A. C., Mah, S. P., Edwards, R. H., & Bredesen, D. E. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.10.4533 · Cited by 619 · see citing works

Neurotrophic Factors Attenuate Glutamate‐Induced Accumulation of Peroxides, Elevation of Intracellular Ca 2+ Concentration, and Neurotoxicity and Increase Antioxidant Enzyme Activities in Hippocampal Neurons

Mattson, M. P., Lovell, M. A., Furukawa, K., & Markesbery, W. R. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.65041740.x · Cited by 615 · see citing works

Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL

Shimizu, S., Eguchi, Y., Kosaka, H., Kamiike, W., Matsuda, H., & Tsujimoto, Y. (1995) · Nature · doi:10.1038/374811a0 · Cited by 611 · see citing works

Rapid Communication: Oxidative Stress Induces Apoptosis in Embryonic Cortical Neurons

Ratan, R. R., Murphy, T. H., & Baraban, J. M. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62010376.x · Cited by 585 · see citing works

Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium

Greene, L. (1978) · The Journal of Cell Biology · doi:10.1083/jcb.78.3.747 · Cited by 432 · see citing works

Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity.

Batistatou, A. K., & Greene, L. A. (1991) · The Journal of Cell Biology · doi:10.1083/jcb.115.2.461 · Cited by 357 · see citing works

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

Rukenstein, A., Rydel, R. E., & Greene, L. (1991) · Journal of Neuroscience · doi:10.1523/jneurosci.11-08-02552.1991 · Cited by 337 · see citing works

Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells.

Troy, C. M., & Shelanski, M. L. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.14.6384 · Cited by 271 · see citing works

A system for characterizing cellular and molecular events in programmed neuronal cell death

Pittman, R. N., Wang, S., DiBenedetto, A. J., & Mills, J. C. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-09-03669.1993 · Cited by 265 · see citing works

Nerve growth factor in mouse and rat serum: correlation between bioassay and radioimmunoassay determinations.

Suda, K., Barde, Y., & Thoenen, H. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.8.4042 · Cited by 245 · see citing works

Induction of apoptosis in catecholaminergic PC12 cells by L-DOPA. Implications for the treatment of Parkinson's disease.

Walkinshaw, G., & Waters, C. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117946 · Cited by 242 · see citing works

Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons

Whittemore, E. R., Loo, D. T., & Cotman, C. W. (1994) · Neuroreport · doi:10.1097/00001756-199407000-00019 · Cited by 205 · see citing works

Technical tips

Sgonc, R., Boeck, G., Dietrich, H., Gruber, J., Recheis, H., & Wick, G. (1994) · Trends in Genetics · doi:10.1016/0168-9525(94)90140-6 · Cited by 184 · see citing works

Role of nerve growth factor in oxidant‐antioxidant balance and neuronal injury. I. Stimulation of hydrogen peroxide resistance

Jackson, G. R., Apffel, L., Werrbach‐Perez, K., & Perez-Polo, J. R. (1990) · Journal of Neuroscience Research · doi:10.1002/jnr.490250313 · Cited by 159 · see citing works

The helix-loop-helix/leucine repeat transcription factor USF can be functionally regulated in a redox-dependent manner.

Pognonec, P., Kato, H., & Roeder, R. G. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)35801-0 · Cited by 127 · see citing works

Survival factor-insensitive generation of reactive oxygen species induced by serum deprivation in neuronal cells

Satoh, T., Sakai, N., Enokido, Y., Uchiyama, Y., & Hatanaka, H. (1996) · Brain Research · doi:10.1016/0006-8993(96)00527-6 · Cited by 114 · see citing works

Survival factor-insensitive generation of reactive oxygen species induced by serum deprivation in neuronal cells

Satoh, T. (1996) · Brain Research · doi:10.1016/s0006-8993(96)00527-6 · Cited by 102 · see citing works

Inhibition of Drug‐Induced Apoptosis by Survival Factors in PC12 Cells

Lindenboim, L., Haviv, R., & Stein, R. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.64031054.x · Cited by 78 · see citing works

Apoptotic cell death occurs in hippocampal neurons cultured in a high oxygen atmosphere

Enokido, Y., & Hatanaka, H. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90041-d · Cited by 74 · see citing works

Neuronal death, cytoplasmic calcium and internucleosomal DNA fragmentation: evidence for DNA fragments being released from cells

Joseph, R., Li, W., & Han, E. (1993) · Molecular Brain Research · doi:10.1016/0169-328x(93)90074-y · Cited by 58 · see citing works

Neuronal differentiation of PC12 cells as a result of prevention of cell death by bcl‐2

Sato, N., Hotta, K., Waguri, S., Nitatori, T., Tohyama, K., Tsujimoto, Y., & Uchiyama, Y. (1994) · Journal of Neurobiology · doi:10.1002/neu.480251005 · Cited by 55 · see citing works

Oxygen-induced apoptosis in PC12 cells with special reference to the role of Bcl-2

Kubo, T., Enokido, Y., Yamada, M., Oka, T., Uchiyama, Y., & Hatanaka, H. (1996) · Brain Research · doi:10.1016/0006-8993(96)00542-2 · Cited by 32 · see citing works

High oxygen atmosphere for neuronal cell culture with nerve growth factor. II. Survival and growth of clonal rat pheochromocytoma PC12h cells

Enokido, Y., & Hatanaka, H. (1990) · Brain Research · doi:10.1016/0006-8993(90)90004-u · Cited by 31 · see citing works

Flow cytometric analysis of serum deprivation-induced apoptosis of PC12 cells, with special reference to role of bcl-2

Satoh, T., Sakai, N., Kubo, T., Enokido, Y., Uchiyama, Y., & Hatanaka, H. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(95)12150-1 · Cited by 15 · see citing works

Reactive oxygen intermediates as mediators of programmed cell death in plants and animals

Jabs, T. (1999) · Biochemical Pharmacology · doi:10.1016/s0006-2952(98)00227-5 · Cited by 591 · see citing works

Thioredoxin Peroxidase Is a Novel Inhibitor of Apoptosis with a Mechanism Distinct from That of Bcl-2

Zhang, P., Liu, B., Kang, S. W., Seo, M. S., Rhee, S. G., & Obeid, L. M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.49.30615 · Cited by 368 · see citing works

Withania somnifera (L.) Dunal (Ashwagandha): A comprehensive review on ethnopharmacology, pharmacotherapeutics, biomedicinal and toxicological aspects

Paul, S., Chakraborty, S., Anand, U., Dey, S., Nandy, S., Ghorai, M., Saha, S. C., Patil, M. T., Kandimalla, R., Proćków, J., et al. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112175 · Cited by 306 · see citing works

Mechanisms underlying hypoxia-induced neuronal apoptosis

Banasiak, K. J., Xia, Y., & Haddad, G. G. (2000) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00011-3 · Cited by 302 · see citing works

Protective effects of salidroside on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells

Zhang, L., Yu, H., Sun, Y., Lin, X., Chen, B., Tan, C., Cao, G.-X., & Wang, Z. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.01.089 · Cited by 262 · see citing works

Cytoprotective effect of fucoxanthin isolated from brown algae Sargassum siliquastrum against H2O2-induced cell damage

Heo, S., Ko, S., Kang, S., Kang, H., Kim, J.-P., Kim, S.-H., Lee, K.-W., Cho, M.-G., & Jeon, Y. (2008) · European Food Research and Technology · doi:10.1007/s00217-008-0918-7 · Cited by 210 · see citing works

Alpinia protocatechuic acid protects against oxidative damage in vitro and reduces oxidative stress in vivo

Shi, G., An, L., Jiang, B., Guan, S., & Bao, Y. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.02.057 · Cited by 199 · see citing works

Distribution of metabotropic glutamate receptor type 1a in Purkinje cell dendritic spines is independent of the presence of presynaptic parallel fibers

Tak�cs, J., Gombos, G., G�rcs, T., Becker, T., de Barry, J., & H�mori, J. (1997) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19971101)50:3 · Cited by 46 · see citing works

Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin

Hong, H., & Liu, G. (2004) · Life Sciences · doi:10.1016/j.lfs.2003.09.074 · Cited by 186 · see citing works

Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP‐1 activation

Zou, W., Yan, M., Xu, W., Huo, H., Sun, L., Zheng, Z., & Liu, X. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1118 · Cited by 185 · see citing works

Is Hydrogen Peroxide a Suitable Apoptosis Inducer for All Cell Types?

Xiang, J., Wan, C., Guo, R., & Guo, D. (2016) · BioMed Research International · doi:10.1155/2016/7343965 · Cited by 162 · see citing works

Strawberry and Its Anthocyanins Reduce Oxidative Stress-Induced Apoptosis in PC12 Cells

Heo, H. J., & Lee, C. Y. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf048616l · Cited by 156 · see citing works

Relationships between neuronal death and the cellular redox status. Focus on the developing nervous system

Castagné, V. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(99)00012-x · Cited by 134 · see citing works

Neuroprotective effect of astaxanthin on H2O2-induced neurotoxicity in vitro and on focal cerebral ischemia in vivo

Lu, Y., Liu, S., Sun, H., Wu, X., Li, J.-J., & Zhu, L. (2010) · Brain Research · doi:10.1016/j.brainres.2010.09.016 · Cited by 128 · see citing works

Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cells

Kwon, S., Kim, J., Hong, S., Jung, Y., Kim, H., Lee, S., & Jang, C. (2011) · Neurochemistry International · doi:10.1016/j.neuint.2011.01.012 · Cited by 118 · see citing works

Generation of free radicals during lipid hydroperoxide-triggered apoptosis in PC12h cells

Aoshima, H., Satoh, T., Sakai, N., Yamada, M., Enokido, Y., Ikeuchi, T., & Hatanaka, H. (1997) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/s0005-2760(96)00159-2 · Cited by 111 · see citing works

Protective effects of ellagic and chlorogenic acids against oxidative stress in PC12 cells

Pavlica, S., & Gebhardt, R. (2005) · Free Radical Research · doi:10.1080/09670260500197660 · Cited by 107 · see citing works

Neuroprotective effects of PDGF against oxidative stress and the signaling pathway involved

Zheng, L., Ishii, Y., Tokunaga, A., Hamashima, T., Shen, J., Zhao, Q., Ishizawa, S., Fujimori, T., Nabeshima, Y., Mori, H., et al. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22302 · Cited by 99 · see citing works

Bcl-2 Facilitates Recovery from DNA Damage after Oxidative Stress

Deng, G., Su, J. H., Ivins, K. J., Houten, B. V., & Cotman, C. W. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7145 · Cited by 99 · see citing works

Attenuation of oxidative neuronal cell death by coffee phenolic phytochemicals

Cho, E. S., Jang, Y. J., Hwang, M. K., Kang, N. J., Lee, K. W., & Lee, H. J. (2008) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2008.10.021 · Cited by 97 · see citing works

Generation of reactive oxygen species, release of l-glutamate and activation of caspases are required for oxygen-induced apoptosis of embryonic hippocampal neurons in culture

Ishikawa, Y., Satoh, T., Enokido, Y., Nishio, C., Ikeuchi, T., & Hatanaka, H. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01108-7 · Cited by 96 · see citing works

Herpes Simplex Virus Type 1 Vector-Mediated Expression of Nerve Growth Factor Protects Dorsal Root Ganglion Neurons from Peroxide Toxicity

Goins, W. F., Lee, K. A., Cavalcoli, J. D., O’Malley, M. E., DeKosky, S. T., Fink, D. J., & Glorioso, J. C. (1999) · Journal of Virology · doi:10.1128/jvi.73.1.519-532.1999 · Cited by 95 · see citing works

HERPES SIMPLEX VIRUS MEDIATED NERVE GROWTH FACTOR EXPRESSION IN BLADDER AND AFFERENT NEURONS: POTENTIAL TREATMENT FOR DIABETIC BLADDER DYSFUNCTION

Goins, W. F., Yoshimura, N., Phelan, M. W., Yokoyama, T., Fraser, M. O., Ozawa, H., Bennett, N., de Groat, W. C., Glorioso, J. C., & Chancellor, M. B. (2001) · The Journal of Urology · doi:10.1016/s0022-5347(05)66407-5 · Cited by 95 · see citing works

Protection of PC12 cells from hydrogen peroxide-induced cytotoxicity by salvianolic acid B, a new compound isolated from Radix Salviae miltiorrhizae

Liu, C.-S., Chen, N., & Zhang, J. (2006) · Phytomedicine · doi:10.1016/j.phymed.2006.11.002 · Cited by 94 · see citing works

Regulation of heme oxygenase-1 expression and MAPK pathways in response to kaempferol and rhamnocitrin in PC12 cells

Hong, J.-T., Yen, J.-H., Wang, L., Lo, Y., Chen, Z., & Wu, M. (2009) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2009.02.014 · Cited by 93 · see citing works

A selenium polysaccharide from Platycodon grandiflorum rescues PC12 cell death caused by H2O2 via inhibiting oxidative stress

Sheng, Y., Liu, G., Wang, M., Lv, Z., & Du, P. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.06.052 · Cited by 90 · see citing works

Antioxidant properties and PC12 cell protective effects of APS-1, a polysaccharide from Aloe vera var. chinensis

Wu, J. H., Chen, X., Shan, C., & Tan, R. X. (2005) · Life Sciences · doi:10.1016/j.lfs.2005.05.097 · Cited by 88 · see citing works

In vitro protective effects of Withania somnifera (L.) dunal root extract against hydrogen peroxide and β‐amyloid(1–42)‐induced cytotoxicity in differentiated PC12 cells

Kumar, S., Seal, C. J., Howes, M. R., Kite, G. C., & Okello, E. J. (2010) · Phytotherapy Research · doi:10.1002/ptr.3261 · Cited by 84 · see citing works

Purification of a Multipotent Antideath Activity from Bovine Liver and Its Identification as Arginase: Nitric Oxide-Independent Inhibition of Neuronal Apoptosis

Esch, F. S., Lin, K., Hills, A., Zaman, K., Baraban, J. M., Chatterjee, S., Rubin, L. L., Ash, D. E., & Ratan, R. R. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-11-04083.1998 · Cited by 83 · see citing works

Local control of mitochondrial membrane potential, permeability transition pore and reactive oxygen species by calcium and calmodulin in rat ventricular myocytes

Odagiri, K., Katoh, H., Kawashima, H., Tanaka, T. L., Ohtani, H., Saotome, M., Urushida, T., Satoh, H., & Hayashi, H. (2009) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2008.12.022 · Cited by 83 · see citing works

Modulation of hydrogen peroxide-induced DNA damage, MAPKs activation and cell death in PC12 by ergothioneine

COLOGNATO, R., LAURENZA, I., FONTANA, I., COPPEDE, F., SICILIANO, G., COECKE, S., ARUOMA, O., BENZI, L., & MIGLIORE, L. (2006) · Clinical Nutrition · doi:10.1016/j.clnu.2005.10.005 · Cited by 81 · see citing works

Synthesis and Characterization of Poly(ethylene glycol)−Glutathione Conjugate Self-Assembled Nanoparticles for Antioxidant Delivery

Williams, S. R., Lepene, B. S., Thatcher, C. D., & Long, T. E. (2008) · Biomacromolecules · doi:10.1021/bm801058j · Cited by 81 · see citing works

The neuroprotective effects of Lonicera japonica THUNB. against hydrogen peroxide-induced apoptosis via phosphorylation of MAPKs and PI3K/Akt in SH-SY5Y cells

Kwon, S., Hong, S., Kim, J., Jung, Y., Kim, S. Y., Kim, H., Lee, S., & Jang, C. (2011) · Food and Chemical Toxicology · doi:10.1016/j.fct.2011.01.008 · Cited by 76 · see citing works

Oxidative‐stress‐dependent up‐regulation of Bcl‐2 expression in the central nervous system of aged Fisher‐344 rats

Kaufmann, J. A., Bickford, P. C., & Taglialatela, G. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00118.x · Cited by 76 · see citing works

Effects of Methylmercury and Mercuric Chloride on Differentiation and Cell Viability in PC12 Cells

Parran, D. K. (2001) · Toxicological Sciences · doi:10.1093/toxsci/59.2.278 · Cited by 75 · see citing works

HYDROGEN PEROXIDE INDUCES APOPTOSIS IN HUMAN HEPATOMA CELLS AND ALTERS CELL REDOX STATUS

Li, J., Huang, C., Zheng, R., Cui, K., & Li, J. (2000) · Cell Biology International · doi:10.1006/cbir.1999.0438 · Cited by 74 · see citing works

Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione

Wilkins, H., Marquardt, K., Lash, L. H., & Linseman, D. A. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.10.495 · Cited by 72 · see citing works

Bcl-XL translocation in renal tubular epithelial cells in vitro protects distal cells from oxidative stress

Cuttle, L., Zhang, X., Endre, Z. H., Winterford, C. M., & Gobe, G. C. (2001) · Kidney International · doi:10.1046/j.1523-1755.2001.0590051779.x · Cited by 68 · see citing works

Forsythiaside Protects Against Hydrogen Peroxide-Induced Oxidative Stress and Apoptosis in PC12 Cell

Huang, C., Lin, Y., Su, H., & Ye, D. (2014) · Neurochemical Research · doi:10.1007/s11064-014-1461-5 · Cited by 68 · see citing works

Neuroprotective effects of orientin on hydrogen peroxide-induced apoptosis in SH-SY5Y cells

LAW, B. N. T., Ling, A. P. K., Koh, R. Y., Chye, S. M., & Wong, Y. P. (2013) · Molecular Medicine Reports · doi:10.3892/mmr.2013.1878 · Cited by 66 · see citing works

Protective effect of lavender oil on scopolamine induced cognitive deficits in mice and H2O2 induced cytotoxicity in PC12 cells

Xu, P., Wang, K., Lu, C., Dong, L., Gao, L., Yan, M., Aibai, S., & Liu, X. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.08.030 · Cited by 64 · see citing works

Antioxidant and angiotensin I converting enzyme inhibitory activity of Bambusae caulis in Liquamen

Je, J., Park, P., Kim, E., & Ahn, C. (2008) · Food Chemistry · doi:10.1016/j.foodchem.2008.08.022 · Cited by 61 · see citing works

Cocoa procyanidins protect PC12 cells from hydrogen-peroxide-induced apoptosis by inhibiting activation of p38 MAPK and JNK

Cho, E. S., Lee, K. W., & Lee, H. J. (2008) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2007.12.012 · Cited by 61 · see citing works

Bis(7)-tacrine, a promising anti-Alzheimer's agent, reduces hydrogen peroxide-induced injury in rat pheochromocytoma cells: comparison with tacrine

Xiao, X. Q., Lee, N. T. K., Carlier, P. R., Pang, Y., & Han, Y. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)01357-4 · Cited by 59 · see citing works

Morroniside Prevents Peroxide-induced Apoptosis by Induction of Endogenous Glutathione in Human Neuroblastoma Cells

Wang, W., Huang, W., Li, L., Hou-xi, A., Sun, F., Liu, C., & An, Y. (2007) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-007-9168-7 · Cited by 59 · see citing works

Oxygen Toxicity Induces Apoptosis in Neuronal Cells

Satoh, T., Enokido, Y., Kubo, T., Yamada, M., & Hatanaka, H. (1998) · Cellular and Molecular Neurobiology · doi:10.1023/a:1020633919115 · Cited by 56 · see citing works

Effects of Banana, Orange, and Apple on Oxidative Stress‐Induced Neurotoxicity in PC12 Cells

Heo, H. J., Choi, S. J., Choi, S., Shin, D. ‐., Lee, J. M., & Lee, C. Y. (2008) · Journal of Food Science · doi:10.1111/j.1750-3841.2007.00632.x · Cited by 55 · see citing works

3′,4′,7-Trihydroxyflavone prevents apoptotic cell death in neuronal cells from hydrogen peroxide-induced oxidative stress

Kwon, S., Hong, S., Ma, S., Lee, S., & Jang, C. (2015) · Food and Chemical Toxicology · doi:10.1016/j.fct.2015.02.014 · Cited by 54 · see citing works

Pulsatile shear stress leads to DNA fragmentation in human SH‐SY5Y neuroblastoma cell line

Triyoso, D. H., & Good, T. A. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.355ac.x · Cited by 54 · see citing works

Functional dichotomy: glutathione and vitamin E in homeostasis relevant to primary open-angle glaucoma

Veach, J. E. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20041113 · Cited by 53 · see citing works

Protection of PC12 cells from hydrogen peroxide-induced injury by EPS2, an exopolysaccharide from a marine filamentous fungus Keissleriella sp. YS4108

Sun, C., Shan, C., Gao, X., & Tan, R. X. (2004) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2004.08.011 · Cited by 52 · see citing works

α7 Nicotinic receptor-mediated protection against ethanol-induced oxidative stress and cytotoxicity in PC12 cells

Li, Y., King, M. A., & Meyer, E. M. (2000) · Brain Research · doi:10.1016/s0006-8993(99)02457-9 · Cited by 52 · see citing works

Comparison of antioxidant activities between salvianolic acid B and Ginkgo biloba extract (EGb 761)

Liu, C.-S., CHENG, Y., Hu, J., Zhang, W., Chen, N., & Zhang, J. (2006) · Acta Pharmacologica Sinica · doi:10.1111/j.1745-7254.2006.00378.x · Cited by 52 · see citing works

The Effect of Tetramethylpyrazine on Hydrogen Peroxide‐Induced Oxidative Damage in Human Umbilical Vein Endothelial Cells

Li, W., Liu, H., Li, X., Wu, J., Xu, G., Teng, Y., Ding, S., & Yu, C. (2009) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/j.1742-7843.2009.00470.x · Cited by 51 · see citing works

Reactive Oxygen Species Mediate Pyridostigmine-Induced Neuronal Apoptosis: Involvement of Muscarinic and NMDA Receptors

Li, L., Shou, Y., Borowitz, J. L., & Isom, G. E. (2001) · Toxicology and Applied Pharmacology · doi:10.1006/taap.2001.9283 · Cited by 49 · see citing works

Luteolin-induced protection of H2O2-induced apoptosis in PC12 cells and the associated pathway

LIN, P., Tian, X., YI, Y.-S., Wen-shi, J., ZHOU, Y.-J., & CHENG, W.-J. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4400 · Cited by 48 · see citing works

Puerarin protects differentiated PC12 cells from H2O2‐induced apoptosis through the PI3K/Akt signalling pathway

Zhang, Q., Huang, W., Lv, X., & Yang, Y. (2011) · Cell Biology International · doi:10.1042/cbi20100900 · Cited by 45 · see citing works

Astragaloside IV attenuates the H2O2-induced apoptosis of neuronal cells by inhibiting α-synuclein expression via the p38 MAPK pathway

Liu, X., Zhang, J., Wang, S., Qiu, J., & Yu, C. (2017) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2017.3157 · Cited by 44 · see citing works

d-β-Hydroxybutyrate inhibited the apoptosis of PC12 cells induced by H2O2 via inhibiting oxidative stress

Cheng, B., Lu, H., Bai, B., & Chen, J. (2012) · Neurochemistry International · doi:10.1016/j.neuint.2012.09.011 · Cited by 42 · see citing works

Passage Variation of PC12 Cells Results in Inconsistent Susceptibility to Externally Induced Apoptosis

Kinarivala, N., Shah, K. K., Abbruscato, T. J., & Trippier, P. C. (2016) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.6b00208 · Cited by 41 · see citing works

Flavonoids from the leaves of Diospyros kaki reduce hydrogen peroxide-induced injury of NG108-15 cells

Bei, W., Peng, W., Ma, Y., & Xu, A. (2005) · Life Sciences · doi:10.1016/j.lfs.2004.09.031 · Cited by 40 · see citing works

Nerve growth factor protects against aluminum-mediated cell death

Ohyashiki, T., Satoh, E., Okada, M., Takadera, T., & Sahara, M. (2002) · Toxicology · doi:10.1016/s0300-483x(02)00139-7 · Cited by 40 · see citing works

In vivo and in vitro neuroprotective effects of maca polysaccharide

Zhou, Y. M., Zhu, L., Li, H., Xie, W., Liu, J., Zhang, Y., Li, Y., & Wang, C. (2022) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2701008 · Cited by 38 · see citing works

Zinc and Copper inhibit nerve growth factor-mediated protection from oxidative stress-induced apoptosis

Wang, W., Post, J. I., Dow, K. E., Shin, S. H., Riopelle, R. J., & Ross, G. M. (1999) · Neuroscience Letters · doi:10.1016/s0304-3940(98)00929-x · Cited by 38 · see citing works

Blockade of SOCE protects HT22 cells from hydrogen peroxide-induced apoptosis

Rao, W., Zhang, L., Su, N., Wang, K., Hui, H., Wang, L., Chen, T., Luo, P., Yang, Y., Liu, Z.-B., et al. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.10.054 · Cited by 40 · see citing works

The neuroprotective effects of ipriflavone against H2O2 and amyloid beta induced toxicity in human neuroblastoma SH-SY5Y cells

Xiao, Z., Huang, C., Wu, J., Sun, L., Hao, W., Leung, L. K., & Huang, J. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.09.023 · Cited by 37 · see citing works

Facet-Dependent Activity of CeO2 Nanozymes Regulate the Fate of Human Neural Progenitor Cell via Redox Homeostasis

Wang, Y., Tan, Z., Zhang, Z., Zhu, P., Tam, S. W., Zhang, Z., Jiang, X., Lin, K., Tian, L., Huang, Z., et al. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c09304 · Cited by 37 · see citing works

Towards resolving the enigma of the dichotomy of resveratrol: cis- and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation

Jhanji, M., Rao, C. N., & Sajish, M. (2020) · GeroScience · doi:10.1007/s11357-020-00295-w · Cited by 36 · see citing works

Neuroprotective Effects of Protocatechuic Aldehyde against Neurotoxin-Induced Cellular and Animal Models of Parkinson’s Disease

Zhao, X. S., Zhai, S., An, M.-S., Wang, Y., Yang, Y.-F., Ge, H.-Q., Liu, J., & Pu, X. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078220 · Cited by 35 · see citing works

Oxidative Stress and the Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Pathway in Multiple Sclerosis: Focus on Certain Exogenous and Endogenous Nrf2 Activators and Therapeutic Plasma Exchange Modulation

Tonev, D. G., & Momchilova, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417223 · Cited by 34 · see citing works

Retinoic acid potentiated the protective effect of NGF against staurosporine-induced apoptosis in cultured chick neurons by increasing the trkA protein expression

Ahlemeyer, B., H�hne, R., & Krieglstein, J. (2000) · Journal of Neuroscience Research · doi:10.1002/1097-4547(20000615)60:6 · Cited by 34 · see citing works

Rhodiola rosea Extract Protects Human Cortical Neurons against Glutamate and Hydrogen Peroxide‐induced Cell Death Through Reduction in the Accumulation of Intracellular Calcium

Palumbo, D. R., Occhiuto, F., Spadaro, F., & Circosta, C. (2011) · Phytotherapy Research · doi:10.1002/ptr.3662 · Cited by 33 · see citing works

VIP provides cellular protection through a specific splice variant of the PACAP receptor: A new neuroprotection target

Pilzer, I., & Gozes, I. (2006) · Peptides · doi:10.1016/j.peptides.2006.06.007 · Cited by 33 · see citing works

Gallic Acid Induces Neuronal Cell Death through Activation of c‐Jun N‐Terminal Kinase and Downregulation of Bcl‐2

Kang, M. K., Kang, N. J., Jang, Y. J., Lee, K. W., & Lee, H. J. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04728.x · Cited by 33 · see citing works

Transfection of C6 glioma cells with glia maturation factor upregulates brain-derived neurotrophic factor and nerve growth factor: trophic effects and protection against ethanol toxicity in cerebellar granule cells

Pantazis, N. J., Zaheer, A., Dai, D., Zaheer, S. A., Green, S. H., & Lim, R. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02194-6 · Cited by 32 · see citing works

Susceptibility of Differentiated Thyrocytes in Primary Culture to Undergo Apoptosis after Exposure to Hydrogen Peroxide: Relation with the Level of Expression of Apoptosis Regulatory Proteins, Bcl-2 and Bax

Riou, C., Tonoli, H., Bernier‐Valentin, F., Rabilloud, R., Fonlupt, P., & Rousset, B. (1999) · Endocrinology · doi:10.1210/en.140.5.1990 · Cited by 32 · see citing works

Neuronal cell protective and antioxidant effects of phenolics obtained from Zanthoxylum piperitum leaf using in vitro model system

Jeong, C., Kwak, J., Kim, J., Choi, G., Kim, D., & Heo, H. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2010.09.022 · Cited by 28 · see citing works

Roles of Ras-Erk in Apoptosis of PC12 Cells Induced by Trophic Factor Withdrawal or Oxidative Stress

Jiang, H., Zhang, L., Koubi, D., Kuo, J., Groc, L., Rodríguez, A. I., Hunter, T. J., Tang, S., Lazarovici, P., Gautam, S. C., et al. (2005) · Journal of Molecular Neuroscience · doi:10.1385/jmn:25:2:133 · Cited by 31 · see citing works

Neuroprotective properties of Loranthus parasiticus aqueous fraction against oxidative stress-induced damage in NG108-15 cells

Wong, D. Z. H., Kadir, H. A., Lee, C. L., & Goh, B. H. (2012) · Journal of Natural Medicines · doi:10.1007/s11418-011-0622-y · Cited by 29 · see citing works

Cytoprotective effects of polyphenolics on H2O2-induced cell death in SH-SY5Y cells in relation to their antioxidant activities

Zhang, J., Melton, L. D., Adaim, A., & Skinner, M. A. (2008) · European Food Research and Technology · doi:10.1007/s00217-008-0915-x · Cited by 29 · see citing works

Protective Effect of Ursolic Acid fromCornus officinalison the Hydrogen Peroxide-Induced Damage of HEI-OC1 Auditory Cells

Yu, H., Hur, J.-M., Seo, S., Moon, H. K., Kim, H., Park, R., & You, Y. (2009) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x0900720x · Cited by 29 · see citing works

Effects of Antioxidant, Anti-Collagenase, Anti-Elastase, Anti-Tyrosinase of The Extract and Fraction From Turbinaria decurrens Bory.

Nurrochmad, A., Wirasti, W., Dirman, A., Lukitaningsih, E., Rahmawati, A., & Fakhrudin, N. (2018) · INDONESIAN JOURNAL OF PHARMACY · doi:10.14499/indonesianjpharm29iss4pp188 · Cited by 28 · see citing works

Protective effects of Orostachys japonicus A. Berger (Crassulaceae) on H2O2-induced apoptosis in GT1-1 mouse hypothalamic neuronal cell line

Yoon, Y., Kim, K.-S., Hong, S.-G., Kang, B.-J., Lee, M. Y., & Cho, D.-W. (2000) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(99)00107-5 · Cited by 28 · see citing works

Cytoprotection by Neutral Fraction of Tannat Red Wine against Oxidative Stress-Induced Cell Death

Echeverry, C., Blasina, F., Arredondo, F., Ferreira, M., Abin‐Carriquiry, J. A., Vásquez, L., Aspillaga, A. A., Diez, M. S., Leighton, F., & Dajas, F. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf040053q · Cited by 28 · see citing works

Glutathione Depletion Promotes Aluminum-Mediated Cell Death of PC12 Cells

Satoh, E., Okada, M., Takadera, T., & Ohyashiki, T. (2005) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.28.941 · Cited by 27 · see citing works

PAK2 activated by Cdc42 and caspase 3 mediates different cellular responses to oxidative stress-induced apoptosis

Huang, J. C., Huang, A., Poplawski, A. A., DiPino, F., Traugh, J. A., & Ling, J. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2020.118645 · Cited by 27 · see citing works

Brain-derived neurotrophic factor prevents superoxide anion-induced death of PC12h cells stably expressing TrkB receptor via modulation of reactive oxygen species

Tomoko, Y., Satoh, T., Ishikawa, Y., Nakatani, A., Yamada, M., Ikeuchi, T., & Hatanaka, H. (1999) · Neuroscience Research · doi:10.1016/s0168-0102(99)00062-0 · Cited by 27 · see citing works

Chamomile Confers Protection against Hydrogen Peroxide‐Induced Toxicity through Activation of Nrf2‐Mediated Defense Response

Bhaskaran, N., Srivastava, J. K., Shukla, S., & Gupta, S. (2012) · Phytotherapy Research · doi:10.1002/ptr.4701 · Cited by 26 · see citing works

Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca2+currents in NTS neurons

Wang, G., Coleman, C. G., Glass, M. J., Zhou, P., Yu, Q., Park, L., Anrather, J., Pickel, V. M., & Iadecola, C. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00571.2011 · Cited by 26 · see citing works

Scutellarin protects PC12 cells from oxidative stress-induced apoptosis

Hong, H., & Liu, G.-Q. (2006) · Journal of Asian Natural Products Research · doi:10.1080/10286020412331286470 · Cited by 25 · see citing works

EGb761 Protects Hydrogen Peroxide-induced Death of Spinal Cord Neurons through Inhibition of Intracellular ROS Production and Modulation of Apoptotic Regulating Genes

Jiang, X., Nie, B., Fu, S., Hu, J., Yin, L., Lin, L., Wang, X., Lu, P., & Xu, X. (2009) · Journal of Molecular Neuroscience · doi:10.1007/s12031-008-9140-0 · Cited by 25 · see citing works

Reactive oxygen species induce cell death via Akt signaling in rat osteoblast-like cell line ROS 17/2.8

Zhang, B., Xie, Q., Quan, Y., Pan, X., & Liao, D. (2013) · Toxicology and Industrial Health · doi:10.1177/0748233713491801 · Cited by 22 · see citing works

Protective effect of trihexyphenidyl on hydrogen peroxide-induced oxidative damage in PC12 cells

Ji, B., & Gao, Y. Z. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.03.089 · Cited by 22 · see citing works

Peroxide mediates ethanol-induced cytotoxicity in PC12 cells

Li, Y., Walker, D. W., & King, M. A. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00484-6 · Cited by 22 · see citing works

Up-Regulation of Nerve Growth Factor in Cholestatic Livers and Its Hepatoprotective Role against Oxidative Stress

Tsai, M., Lin, Y., Sun, C., Huang, S., Lee, P., & Kao, Y. H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112113 · Cited by 21 · see citing works

Generation of Free Radicals during the Death of Saccharomyces cerevisiae Caused by Lipid Hydroperoxide

Aoshima, H., KADOYA, K., Taniguchi, H., Satoh, T., & Hatanaka, H. (1999) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.63.1025 · Cited by 21 · see citing works

The Fruits of Wampee Inhibit H2O2-Induced Apoptosis in PC12 Cells via the NF-κB Pathway and Regulation of Cellular Redox Status

Zeng, X., Zhou, X., Cui, L., Liu, D., Wu, K., Li, W., & Huang, R. (2014) · Molecules · doi:10.3390/molecules19067368 · Cited by 20 · see citing works

Engineering Modular, Oxygen‐Generating Microbeads for the In Situ Mitigation of Cellular Hypoxia

Accolla, R. P., Liang, J., Lansberry, T. R., Labrada, I. M., Loaisiga, M., Sardi, B. L., & Stabler, C. L. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202300239 · Cited by 19 · see citing works

Augmenter of liver regeneration plays a protective role against hydrogen peroxide-induced oxidative stress in renal proximal tubule cells

Xia, N., Yan, R., Liu, Q., Liao, X., Sun, H., Guo, H. M., & Zhang, L. (2015) · APOPTOSIS · doi:10.1007/s10495-015-1096-2 · Cited by 18 · see citing works

Antioxidant Effect of Melatonin in Human Retinal Neuron Cultures

Lee, M. C., Chung, Y.-T., Lee, J.-H., Jung, J.-J., Kim, H.-S., & Kim, S. U. (2001) · Experimental Neurology · doi:10.1006/exnr.2001.7793 · Cited by 18 · see citing works

Regulation of Reactive Oxygen Species by Nerve Growth Factor but not Bcl-2 as a Novel Mechanism of Protection of PC12 Cells from Superoxide Anion-Induced Death

Satoh, T., Yamagata, T., Ishikawa, Y., YAMADA, M., Uchiyama, Y., & Hatanaka, H. (1999) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a022374 · Cited by 26 · see citing works

The rescuing effect of nerve growth factor is the result of up-regulation of bcl-2 in hyperoxia-induced apoptosis of a subclone of pheochromocytoma cells, PC12h

Katoh, S., Mitsui, Y., Kitani, K., & Suzuki, T. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00582-x · Cited by 25 · see citing works

Protection of oxidative preconditioning against apoptosis induced by H2O2 in PC12 cells: Mechanisms via MMP, ROS, and Bcl-2

Tang, X., Feng, J., Chen, J., Chen, P., Zhi, J., Cui, Y., Guo, R., & Yu, H. (2005) · Brain Research · doi:10.1016/j.brainres.2005.07.072 · Cited by 136 · see citing works

Nerve growth factor and forskolin prevent H2O2-induced apoptosis in PC12 cells by glutathione independent mechanism

Kamata, H., Tanaka, C., Yagisawa, H., & Hirata, H. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(96)12806-8 · Cited by 63 · see citing works

Hydrogen Peroxide-Induced PC12 Cells Apoptosis and the Protective Effect of Paeoniflorin

Rong, S., Wu, D., Zuo-ping, Z., Yi, Y.-P., & Liu, G. (2006) · Zhōnghuá yàoxué zázhì · Cited by 1 · see citing works