Roeder, Kathryn

Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder

An, J.-Y., Lin, K., Zhu, L., Werling, D. M., Dong, S., Brand, H., Wang, H. Z., Zhao, X., Schwartz, G. B., Collins, R. L., et al. (2018) · Science

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 316

Integrated Model of De Novo and Inherited Genetic Variants Yields Greater Power to Identify Risk Genes

He, X., Sanders, S. J., Liu, L., De Rubeis, S., Lim, E. T., Sutcliffe, J. S., Schellenberg, G. D., Gibbs, R. A., Daly, M. J., Buxbaum, J. D., et al. (2013) · PLoS Genetics

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 304

An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder

Werling, D. M., Brand, H., An, J.-Y., Stone, M. R., Zhu, L., Glessner, J. T., Collins, R. L., Dong, S., Layer, R. M., Markenscoff-Papadimitriou, E., et al. (2018) · Nature Genetics

Autism Spectrum Disorder ResearchGenetic Associations and Epidemiology

Cited by 293

Rare Complete Knockouts in Humans: Population Distribution and Significant Role in Autism Spectrum Disorders

Lim, E. T., Raychaudhuri, S., Sanders, S. J., Stevens, C., Sabo, A., MacArthur, D. G., Neale, B. M., Kirby, A., Ruderfer, D. M., Fromer, M., et al. (2013) · Neuron

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 266

APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer’s disease

Nguyen, A. T., Wang, K., Hu, G., Wang, X., Miao, Z., Azevedo, J. A., Suh, E., Van Deerlin, V. M., Choi, D., Roeder, K., et al. (2020) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 241

Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens

Morris, J. A., Caragine, C., Daniloski, Z., Domingo, J., Barry, T., Lu, L., Davis, K., Ziosi, M., Glinos, D. A., Hao, S., et al. (2023) · Science

Genetic Associations and EpidemiologyCRISPR and Genetic Engineering

Cited by 208

Genomic Control to the extreme

Devlin, B., Bacanu, S.-A., & Roeder, K. (2004) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 157

Transcriptional consequences of 16p11.2 deletion and duplication in mouse cortex and multiplex autism families

Blumenthal, I., Ragavendran, A., Erdin, S., Klei, L., Sugathan, A., Guide, J. R., Manavalan, P., Zhou, J. Q., Wheeler, V. C., Levin, J. Z., et al. (2014) · The American Journal of Human Genetics

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 145

Analysis of Rare, Exonic Variation amongst Subjects with Autism Spectrum Disorders and Population Controls

Liu, L., Sabo, A., Neale, B. M., Nagaswamy, U., Stevens, C., Lim, E., Bodea, C. A., Muzny, D., Reid, J. G., Banks, E., et al. (2013) · PLoS Genetics

Autism Spectrum Disorder ResearchGenomics and Rare Diseases

Cited by 135

On the Use of General Control Samples for Genome-wide Association Studies: Genetic Matching Highlights Causal Variants

Luca, D., Ringquist, S., Klei, L., Lee, A. B., Gieger, C., Wichmann, H.-E., Schreiber, S., Krawczak, M., Lu, Y., Styche, A., et al. (2008) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 128

Discovering genetic ancestry using spectral graph theory

Lee, A. B., Luca, D., Klei, L., Devlin, B., & Roeder, K. (2010) · Genetic Epidemiology

Forensic and Genetic ResearchGenetic Associations and Epidemiology

Cited by 108

Do common variants play a role in risk for autism? Evidence and theoretical musings

Devlin, B., Melhem, N., & Roeder, K. (2011) · Brain Research

Autism Spectrum Disorder ResearchGenetic Associations and Epidemiology

Cited by 105

Common risk variants identified in autism spectrum disorder

Grove, J., Ripke, S., Als, T. D., Mattheisen, M., Walters, R., Won, H., Pallesen, J., Agerbo, E., Andreassen, O. A., Anney, R., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory)

Autism Spectrum Disorder ResearchGenetic Associations and Epidemiology

Cited by 89

SCEPTRE improves calibration and sensitivity in single-cell CRISPR screen analysis

Barry, T., Wang, X., Morris, J. A., Roeder, K., & Katsevich, E. (2021) · Genome Biology

Single-cell and spatial transcriptomicsCRISPR and Genetic Engineering

Cited by 86

Heritable variation, with little or no maternal effect, accounts for recurrence risk to autism spectrum disorder in Sweden

Yip, B. H. K., Bai, D., Mahjani, B., Klei, L., Pawitan, Y., Hultman, C. M., Grice, D. E., Roeder, K., Buxbaum, J. D., Devlin, B., et al. (2018) · Biological Psychiatry

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 46

Robust differential expression testing for single-cell CRISPR screens at low multiplicity of infection

Barry, T., Mason, K., Roeder, K., & Katsevich, E. (2024) · Genome Biology

Single-cell and spatial transcriptomicsCRISPR and Genetic Engineering

Cited by 28

H‐MAGMA, inheriting a shaky statistical foundation, yields excess false positives

Yurko, R., Roeder, K., Devlin, B., & G'Sell, M. (2021) · Annals of Human Genetics

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 23

Report of the Ad Hoc Committee on Double-Blind Refereeing

Cox, D., Gleser, L., Perlman, M., Reid, N., & Roeder, K. (1993) · Statistical Science

Publishing and Scholarly CommunicationAcademic Writing and Publishing

Cited by 21

Using ancestry matching to combine family-based and unrelated samples for genome-wide association studies

Crossett, A., Kent, B. P., Klei, L., Ringquist, S., Trucco, M., Roeder, K., & Devlin, B. (2010) · Statistics in Medicine

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 15