Jain, Mohit

Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation

Jain, M., Nilsson, R., Sharma, S., Madhusudhan, N., Kitami, T., Souza, A. L., Kafri, R., Kirschner, M. W., Clish, C. B., & Mootha, V. K. (2012) · Science

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 1,403

Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer

Nilsson, R., Jain, M., Madhusudhan, N., Sheppard, N. G., Strittmatter, L., Kampf, C., Huang, J., Asplund, A., & Mootha, V. K. (2014) · Nature Communications

Cancer, Hypoxia, and MetabolismFolate and B Vitamins Research

Cited by 607

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

Qin, Y., Havulinna, A. S., Liu, Y., Jousilahti, P., Ritchie, S. C., Tokolyi, A., Sanders, J. G., Valsta, L., Brożyńska, M., Zhu, Q., et al. (2022) · Nature Genetics

Gut microbiota and healthGenetic Associations and Epidemiology

Cited by 586

The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition

Luongo, T. S., Lambert, J. P., Yuan, A., Zhang, X., Gross, P., Song, J., Shanmughapriya, S., Gao, E., Jain, M., Houser, S. R., et al. (2015) · Cell Reports

Mitochondrial Function and PathologyCardiac Ischemia and Reperfusion

Cited by 384

Fructose stimulated de novo lipogenesis is promoted by inflammation

Todoric, J., Di Caro, G., Reibe, S., Henstridge, D. C., Green, C. R., Vrbanac, A., Ceteci, F., Conche, C., McNulty, R., Shalapour, S., et al. (2020) · Nature Metabolism

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 328

Effects of diet versus gastric bypass on metabolic function in diabetes

Yoshino, M., Kayser, B. D., Yoshino, J., Stein, R. I., Reeds, D., Eagon, J. C., Eckhouse, S. R., Watrous, J. D., Jain, M., Knight, R., et al. (2020) · New England Journal of Medicine

Bariatric Surgery and OutcomesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 246

Titration of mitochondrial fusion rescues Mff -deficient cardiomyopathy

Chen, H., Ren, S., Clish, C., Jain, M., Mootha, V., McCaffery, J. M., & Chan, D. C. (2015) · Journal of Cell Biology

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 168

Decreased Adipose Tissue Oxygenation Associates with Insulin Resistance in Individuals with Obesity

Cifarelli, V., Beeman, S. C., Smith, G. I., Yoshino, J., Morozov, D., Beals, J. W., Kayser, B. D., Watrous, J. D., Jain, M., Patterson, B. W., et al. (2020) · Journal of Clinical Investigation

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 132

Metabolic programs of T cell tissue residency empower tumour immunity

Reina-Campos, M., Heeg, M., Kennewick, K., Mathews, I. T., Galletti, G., Luna, V., Nguyen, Q., Huang, H., Milner, J. J., Hu, K. H., et al. (2023) · Nature

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 132

The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation

Gustafsson Sheppard, N., Jarl, L., Mahadessian, D., Strittmatter, L., Schmidt, A., Madhusudan, N., Tegnér, J., Lundberg, E. K., Asplund, A., Jain, M., et al. (2015) · Scientific Reports

Folate and B Vitamins ResearchBiochemical and Molecular Research

Cited by 115

Statistical workflow for feature selection in human metabolomics data

Antonelli, J., Claggett, B. L., Henglin, M., Kim, A., Ovsak, G., Kim, N., Deng, K., Rao, K., Tyagi, O., Watrous, J. D., et al. (2019) · Metabolites

Metabolomics and Mass Spectrometry StudiesGene expression and cancer classification

Cited by 88

Genome-wide CRISPR/Cas9 screening in human iPS derived cardiomyocytes uncovers novel mediators of doxorubicin cardiotoxicity

Sapp, V., Aguirre, A., Mainkar, G., Ding, J., Adler, E., Liao, R., Sharma, S., & Jain, M. (2021) · Scientific Reports

CRISPR and Genetic EngineeringChemotherapy-induced cardiotoxicity and mitigation

Cited by 40

Tackling the Complexity of the Exposome: Considerations from the Gunma University Initiative for Advanced Research (GIAR) Exposome Symposium

Zhang, P., Arora, M., Chaleckis, R., Isobe, T., Jain, M., Meister, I., Melén, E., Perzanowski, M., Torta, F., Wenk, M. R., et al. (2019) · Metabolites

Health, Environment, Cognitive AgingEpigenetics and DNA Methylation

Cited by 27

Higher docosahexaenoic acid levels lower the protective impact of eicosapentaenoic acid on long-term major cardiovascular events

Le, V. T., Knight, S., Watrous, J. D., Najhawan, M., Dao, K., McCubrey, R. O., Bair, T. L., Horne, B. D., May, H. T., Muhlestein, J. B., et al. (2023) · Frontiers in Cardiovascular Medicine

Fatty Acid Research and HealthNutritional Studies and Diet

Cited by 18