West, A. Phillip

Mitochondrial DNA stress primes the antiviral innate immune response

West, A. P., Khoury-Hanold, W., Staron, M., Tal, M. C., Pineda, C. M., Lang, S. M., Bestwick, M., Duguay, B. A., Raimundo, N., MacDuff, D. A., et al. (2015) · Nature

interferon and immune responsesImmune Response and Inflammation

Cited by 1,975

Tlr signalling augments macrophage bactericidal activity through mitochondrial ros

West, A. P., Brodsky, I. E., Rahner, C., Woo, D. K., Erdjument-Bromage, H., Tempst, P., Walsh, M. C., Choi, Y., Shadel, G. S., & Ghosh, S. (2011) · Nature

Immune Response and InflammationNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 1,659

Mitochondria in innate immune responses

West, A. P., Shadel, G. S., & Ghosh, S. (2011) · Nature Reviews Immunology

Immune Response and InflammationMitochondrial Function and Pathology

Cited by 1,376

NF-κB and the immune response

Hayden, M. S., West, A. P., & Ghosh, S. (2006) · Oncogene

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 1,178

Mitochondrial DNA in innate immune responses and inflammatory pathology

West, A. P., & Shadel, G. S. (2017) · Nature Reviews Immunology

Immune Response and Inflammationinterferon and immune responses

Cited by 1,115

Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA

Rongvaux, A., Jackson, R., Harman, C. C. D., Li, T., West, A. P., de Zoete, M. R., Wu, Y., Yordy, B., Lakhani, S. A., Kuan, C.-Y., et al. (2014) · Cell

interferon and immune responsesCell death mechanisms and regulation

Cited by 847

A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1

Zhao, B., Du, F., Xu, P., Shu, C., Sankaran, B., Bell, S. L., Liu, M., Lei, Y., Gao, X., Fu, X., et al. (2019) · Nature

interferon and immune responsesImmune Response and Inflammation

Cited by 447

The molecular basis of tight nuclear tethering and inactivation of cGAS

Zhao, B., Xu, P., Rowlett, C. M., Jing, T., Shinde, O., Lei, Y., West, A. P., Liu, W. R., & Li, P. (2020) · Nature

interferon and immune responsesDNA and Nucleic Acid Chemistry

Cited by 261