Karki, Rajendra

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

Karki, R., Sharma, B. R., Tuladhar, S., Williams, E. P., Zalduondo, L., Samir, P., Zheng, M., Sundaram, B., Banoth, B., Malireddi, R. K. S., et al. (2021) · Cell

COVID-19 Clinical Research Studiesinterferon and immune responses

Cited by 1,734

ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways

Kuriakose, T., Man, S. M., Subbarao Malireddi, R. K., Karki, R., Kesavardhana, S., Place, D. E., Neale, G., Vogel, P., & Kanneganti, T.-D. (2016) · Science Immunology

interferon and immune responsesInflammasome and immune disorders

Cited by 818

Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

Christgen, S., Zheng, M., Kesavardhana, S., Karki, R., Malireddi, R. K. S., Banoth, B., Place, D. E., Briard, B., Sharma, B. R., Tuladhar, S., et al. (2020) · Frontiers in Cellular and Infection Microbiology

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 588

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

Man, S. M., Karki, R., Malireddi, R. K. S., Neale, G., Vogel, P., Yamamoto, M., Lamkanfi, M., & Kanneganti, T.-D. (2015) · Nature Immunology

Inflammasome and immune disordersinterferon and immune responses

Cited by 380

AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity

Man, S. M., Karki, R., & Kanneganti, T. (2016) · European Journal of Immunology

Inflammasome and immune disordersinterferon and immune responses

Cited by 354

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes

Man, S. M., Karki, R., Sasai, M., Place, D. E., Kesavardhana, S., Temirov, J., Frase, S., Zhu, Q., Malireddi, R. K. S., Kuriakose, T., et al. (2016) · Cell

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 312

Concerted Activation of the AIM2 and NLRP3 Inflammasomes Orchestrates Host Protection against Aspergillus Infection

Karki, R., Man, S. M., Malireddi, R. K. S., Gurung, P., Vogel, P., Lamkanfi, M., & Kanneganti, T.-D. (2015) · Cell Host & Microbe

Inflammasome and immune disordersAntifungal resistance and susceptibility

Cited by 272

ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis)

Banoth, B., Tuladhar, S., Karki, R., Sharma, B. R., Briard, B., Kesavardhana, S., Burton, A., & Kanneganti, T.-D. (2020) · Journal of Biological Chemistry

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 237

RIPK1 Distinctly Regulates Yersinia-Induced Inflammatory Cell Death, PANoptosis

Malireddi, R. K. S., Kesavardhana, S., Karki, R., Kancharana, B., Burton, A. R., & Kanneganti, T.-D. (2020) · ImmunoHorizons

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 224

Regulated cell death pathways and their roles in homeostasis, infection, inflammation, and tumorigenesis

Lee, E., Song, C.-H., Bae, S.-J., Ha, K.-T., & Karki, R. (2023) · Experimental & Molecular Medicine

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 164

Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging

Luo, H., Mu, W.-C., Karki, R., Chiang, H.-H., Mohrin, M., Shin, J. J., Ohkubo, R., Ito, K., Kanneganti, T.-D., & Chen, D. (2019) · Cell Reports

Inflammasome and immune disordersHematopoietic Stem Cell Transplantation

Cited by 161

ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming

Place, D. E., Samir, P., Karki, R., Briard, B., Vogel, P., & Kanneganti, T.-D. (2018) · The American Journal of Pathology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 22