Yang, Hui

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

Wang, H., Yang, H., Shivalila, C. S., Dawlaty, M. M., Cheng, A. W., Zhang, F., & Jaenisch, R. (2013) · Cell

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 3,495

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

Yang, H., Wang, H., Shivalila, C. S., Cheng, A. W., Shi, L., & Jaenisch, R. (2013) · Cell

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 1,596

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

Zuo, E., Sun, Y., Wei, W., Yuan, T., Ying, W., Sun, H., Yuan, L., Steinmetz, L. M., Li, Y., & Yang, H. (2019) · Science

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 782

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis

Zhou, C., Sun, Y., Yan, R., Liu, Y., Zuo, E., Gu, C., Han, L., Wei, Y., Hu, X., Zeng, R., et al. (2019) · Nature

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 482

Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice

Zhou, H., Su, J., Hu, X., Zhou, C., Li, H., Chen, Z., Xiao, Q., Wang, B., Wu, W., Sun, Y., et al. (2020) · Cell

CRISPR and Genetic EngineeringRetinal Development and Disorders

Cited by 437

Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes

Xu, C., Zhou, Y., Xiao, Q., He, B., Geng, G., Wang, Z., Cao, B., Dong, X., Bai, W., Wang, Y., et al. (2021) · Nature Methods

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 351

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice

Zhou, H., Liu, J., Zhou, C., Gao, N., Rao, Z., Li, H., Hu, X., Li, C., Yao, X., Shen, X., et al. (2018) · Nature Neuroscience

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 276

High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects

Tong, H., Huang, J., Xiao, Q., He, B., Dong, X., Liu, Y., Yang, X., Han, D., Wang, Z., Wang, X., et al. (2023) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 230

A dual inhibition: microRNA-552 suppresses both transcription and translation of cytochrome P450 2E1

Miao, L., Yao, H., Li, C., Pu, M., Yao, X., Yang, H., Qi, X., Ren, J., & Wang, Y. (2016) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 98

Rescue of autosomal dominant hearing loss by in vivo delivery of mini dCas13X-derived RNA base editor

Xiao, Q., Xu, Z., Xue, Y., Xu, C., Han, L., Liu, Y., Wang, F., Zhang, R., Han, S., Wang, X., et al. (2022) · Science Translational Medicine

CRISPR and Genetic EngineeringHearing, Cochlea, Tinnitus, Genetics

Cited by 95

CasRx-mediated RNA targeting prevents choroidal neovascularization in a mouse model of age-related macular degeneration

Zhou, C., Hu, X., Tang, C., Liu, W., Wang, S., Zhou, Y., Zhao, Q., Bo, Q., Shi, L., Sun, X., et al. (2020) · National Science Review

CRISPR and Genetic EngineeringRetinal Diseases and Treatments

Cited by 69

Mini-dCas13X–mediated RNA editing restores dystrophin expression in a humanized mouse model of Duchenne muscular dystrophy

Li, G., Jin, M., Li, Z., Xiao, Q., Lin, J., Yang, D., Liu, Y., Wang, X., Xie, L., Ying, W., et al. (2023) · Journal of Clinical Investigation

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 44