Concannon, Patrick

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

The Type 1 Diabetes Genetics Consortium, Barrett, J. C., Clayton, D. G., Concannon, P., Akolkar, B., Cooper, J. D., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., et al. (2009) · Nature Genetics

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 1,746

Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor

Smith, M. I., Yatsunenko, T., Manary, M. J., Trehan, I., Mkakosya, R., Cheng, J., Kau, A. L., Rich, S. S., Concannon, P., Mychaleckyj, J. C., et al. (2013) · Science

Gut microbiota and healthChild Nutrition and Water Access

Cited by 1,173

Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome

Varon, R., Vissinga, C., Platzer, M., Cerosaletti, K. M., Chrzanowska, K. H., Saar, K., Beckmann, G., Seemanová, E., Cooper, P. R., Nowak, N. J., et al. (1998) · Cell

DNA Repair MechanismsImmunodeficiency and Autoimmune Disorders

Cited by 1,079

Genetics of type 1A diabetes

Concannon, P., Rich, S. S., & Nepom, G. T. (2009) · New England Journal of Medicine

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 510

ATM-dependent phosphorylation of nibrin in response to radiation exposure

Gatei, M., Young, D., Cerosaletti, K. M., Desai-Mehta, A., Spring, K., Kozlov, S., Lavin, M. F., Gatti, R. A., Concannon, P., & Khanna, K. (2000) · Nature Genetics

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 468

Cytomegalovirus infection enhances the immune response to influenza

Furman, D., Jojic, V., Sharma, S., Shen-Orr, S. S., L. Angel, C. J., Onengut-Gumuscu, S., Kidd, B. A., Maecker, H. T., Concannon, P., Dekker, C. L., et al. (2015) · Science Translational Medicine

Cytomegalovirus and herpesvirus researchImmune responses and vaccinations

Cited by 332

Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes

Robertson, C. C., Inshaw, J. R. J., Onengut-Gumuscu, S., Chen, W.-M., Santa Cruz, D. F., Yang, H., Cutler, A. J., Crouch, D. J. M., Farber, E., Bridges, S. L., et al. (2021) · Nature Genetics

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 302

HLA Class I and Genetic Susceptibility to Type 1 Diabetes

Noble, J. A., Valdes, A. M., Varney, M. D., Carlson, J. A., Moonsamy, P., Fear, A. L., Lane, J. A., Lavant, E., Rappner, R., Louey, A., et al. (2010) · Diabetes

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 254

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

EMBRACE, Kuchenbaecker, K. B., Collaborators, G. S., Breast Cancer Family Registry, HEBON, KConFab Investigators, Australian Cancer Study (Ovarian Cancer Investigators), Australian Ovarian Cancer Study Group, the Consortium of Investigators of Modifiers of BRCA1 and BRCA2, Ramus, S. J., et al. (2015) · Nature Genetics

BRCA gene mutations in cancerOvarian cancer diagnosis and treatment

Cited by 250

Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control

Wright, J. A., Keegan, K. S., Herendeen, D. R., Bentley, N. J., Carr, A. M., Hoekstra, M. F., & Concannon, P. (1998) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 226

Chk2 Activation Dependence on Nbs1 after DNA Damage

Buscemi, G., Savio, C., Zannini, L., Miccichè, F., Masnada, D., Nakanishi, M., Tauchi, H., Komatsu, K., Mizutani, S., Khanna, K., et al. (2001) · Molecular and Cellular Biology

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 201

Distinct Functional Domains of Nibrin Mediate Mre11 Binding, Focus Formation, and Nuclear Localization

Desai-Mehta, A., Cerosaletti, K. M., & Concannon, P. (2001) · Molecular and Cellular Biology

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 196

Population-Based Study of the Risk of Second Primary Contralateral Breast Cancer Associated With Carrying a Mutation in BRCA1 or BRCA2

Malone, K. E., Begg, C. B., Haile, R. W., Borg, A., Concannon, P., Tellhed, L., Xue, S., Teraoka, S., Bernstein, L., Capanu, M., et al. (2010) · Journal of Clinical Oncology

BRCA gene mutations in cancerMultiple and Secondary Primary Cancers

Cited by 191

CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients

Fløyel, T., Brorsson, C., Nielsen, L. B., Miani, M., Bang-Berthelsen, C. H., Friedrichsen, M., Overgaard, A. J., Berchtold, L. A., Wiberg, A., Poulsen, P., et al. (2014) · Proceedings of the National Academy of Sciences

Diabetes and associated disordersPancreatic function and diabetes

Cited by 104

Nibrin Forkhead-associated Domain and Breast Cancer C-terminal Domain Are Both Required for Nuclear Focus Formation and Phosphorylation

Cerosaletti, K. M., & Concannon, P. (2003) · Journal of Biological Chemistry

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 74