Shay, Jerry W.

Does a Sentinel or a Subset of Short Telomeres Determine Replicative Senescence?

Zou, Y., Sfeir, A., Gryaznov, S. M., Shay, J. W., & Wright, W. E. (2004) · Molecular Biology of the Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 293

In vivo Inhibition of Lung Cancer by GRN163L: A Novel Human Telomerase Inhibitor

Dikmen, Z. G., Gellert, G. C., Jackson, S., Gryaznov, S., Tressler, R., Dogan, P., Wright, W. E., & Shay, J. W. (2005) · Cancer Research

Telomeres, Telomerase, and SenescenceDNA and Nucleic Acid Chemistry

Cited by 271

Telomeropathies: An emerging spectrum disorder

Holohan, B., Wright, W. E., & Shay, J. W. (2014) · Journal of Cell Biology

Telomeres, Telomerase, and SenescenceNuclear Structure and Function

Cited by 175

Telomeres and aging

Shay, J. W. (2018) · Current Opinion in Cell Biology

Telomeres, Telomerase, and SenescenceNuclear Structure and Function

Cited by 174

Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis

Miura, N., Horikawa, I., Nishimoto, A., Ohmura, H., Ito, H., Hirohashi, S., Shay, J. W., & Oshimura, M. (1997) · Cancer Genetics and Cytogenetics

Telomeres, Telomerase, and SenescenceLiver physiology and pathology

Cited by 174

Targeting telomerase for cancer therapeutics

Shay, J. W., & Keith, W. N. (2008) · British Journal of Cancer

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 171

Galactic cosmic ray simulation at the NASA Space Radiation Laboratory

Norbury, J. W., Schimmerling, W., Slaba, T. C., Azzam, E. I., Badavi, F. F., Baiocco, G., Benton, E., Bindi, V., Blakely, E. A., Blattnig, S. R., et al. (2016) · Life Sciences in Space Research

Radiation Therapy and DosimetryEffects of Radiation Exposure

Cited by 155

Comparison of the telomeric repeat amplification protocol (TRAP) to the new TRAP-eze telomerase detection kit

Holt, S. E., Norton, J. C., Wright, W. E., & Shay, J. W. (1996) · Methods in Cell Science

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 131

Quantitative mitochondrial DNA copy number determination using droplet digital PCR with single-cell resolution

O'Hara, R., Tedone, E., Ludlow, A., Huang, E., Arosio, B., Mari, D., & Shay, J. W. (2019) · Genome Research

Mitochondrial Function and PathologyMolecular Biology Techniques and Applications

Cited by 121

Function of AP-1 in Transcription of the Telomerase Reverse Transcriptase Gene (TERT) in Human and Mouse Cells

Takakura, M., Kyo, S., Inoue, M., Wright, W. E., & Shay, J. W. (2005) · Molecular and Cellular Biology

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 107

Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression

Wood, L. D., Halvorsen, T. L., Dhar, S., Baur, J. A., Pandita, R. K., Wright, W. E., Hande, M. P., Calaf, G., Hei, T. K., Levine, F., et al. (2001) · Oncogene

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 91

Selective targeting of mutant adenomatous polyposis coli ( APC ) in colorectal cancer

Zhang, L., Theodoropoulos, P. C., Eskiocak, U., Wang, W., Moon, Y.-A., Posner, B., Williams, N. S., Wright, W. E., Kim, S. B., Nijhawan, D., et al. (2016) · Science Translational Medicine

Colorectal Cancer Treatments and StudiesWnt/β-catenin signaling in development and cancer

Cited by 88

Genotoxicity of Cytolethal Distending Toxin (CDT) on Isogenic Human Colorectal Cell Lines: Potential Promoting Effects for Colorectal Carcinogenesis

Graillot, V., Dormoy, I., Dupuy, J., Shay, J. W., Huc, L., Mirey, G., & Vignard, J. (2016) · Frontiers in Cellular and Infection Microbiology

Carcinogens and Genotoxicity AssessmentEscherichia coli research studies

Cited by 87

Antiadhesive Effects of GRN163L—An Oligonucleotide N3′→P5′ Thio-Phosphoramidate Targeting Telomerase

Jackson, S. R., Zhu, C.-H., Paulson, V., Watkins, L., Dikmen, Z. G., Gryaznov, S. M., Wright, W. E., & Shay, J. W. (2007) · Cancer Research

Telomeres, Telomerase, and SenescenceRNA Interference and Gene Delivery

Cited by 72

DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging

Sepe, S., Rossiello, F., Cancila, V., Iannelli, F., Matti, V., Cicio, G., Cabrini, M., Marinelli, E., Alabi, B. R., di Lillo, A., et al. (2022) · The EMBO Reports

Telomeres, Telomerase, and SenescenceSARS-CoV-2 and COVID-19 Research

Cited by 42

CDDO-Me protects against space radiation-induced transformation of human colon epithelial cells

Eskiocak, U., Kim, S. B., Roig, A. I., Kitten, E., Batten, K., Cornelius, C., Zou, Y. S., Wright, W. E., & Shay, J. W. (2010) · Radiation Research

Effects of Radiation ExposureRadiation Therapy and Dosimetry

Cited by 36

Decellularized mice colons as models to study the contribution of the extracellular matrix to cell behavior and colon cancer progression

Alabi, B. R., LaRanger, R., & Shay, J. W. (2019) · Acta Biomaterialia

Tissue Engineering and Regenerative MedicineCellular Mechanics and Interactions

Cited by 34

CDDO-Me Protects Normal Lung and Breast Epithelial Cells but Not Cancer Cells from Radiation

El-Ashmawy, M., Delgado, O., Cardentey, A., Wright, W. E., & Shay, J. W. (2014) · PLoS ONE

Effects of Radiation ExposureRadiation Therapy and Dosimetry

Cited by 19

Age-dependent alterations of c-fos and growth regulation in human fibroblasts expressing the HPV16 E6 protein.

Yan, Y., Ouellette, M. M., Shay, J. W., & Wright, W. E. (1996) · Molecular Biology of the Cell

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 9