Thannickal, Victor J.

The Myofibroblast

Hinz, B., Phan, S. H., Thannickal, V. J., Galli, A., Bochaton-Piallat, M.-L., & Gabbiani, G. (2007) · The American Journal of Pathology

Liver physiology and pathologyInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 2,068

Recent Developments in Myofibroblast Biology

Hinz, B., Phan, S. H., Thannickal, V. J., Prunotto, M., Desmoulière, A., Varga, J., De Wever, O., Mareel, M., & Gabbiani, G. (2012) · The American Journal of Pathology

Wound Healing and TreatmentsLiver physiology and pathology

Cited by 1,193

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

Liu, G., Friggeri, A., Yang, Y., Milosevic, J., Ding, Q., Thannickal, V. J., Kaminski, N., & Abraham, E. (2010) · Journal of Experimental Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisMicroRNA in disease regulation

Cited by 935

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

Hecker, L., Vittal, R., Jones, T., Jagirdar, R., Luckhardt, T. R., Horowitz, J. C., Pennathur, S., Martinez, F. J., & Thannickal, V. J. (2009) · Nature Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisRedox biology and oxidative stress

Cited by 852

Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance

Hecker, L., Logsdon, N. J., Kurundkar, D., Kurundkar, A., Bernard, K., Hock, T., Meldrum, E., Sanders, Y. Y., & Thannickal, V. J. (2014) · Science Translational Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisRedox biology and oxidative stress

Cited by 686

Glycolytic Reprogramming in Myofibroblast Differentiation and Lung Fibrosis

Xie, N., Tan, Z., Banerjee, S., Cui, H., Ge, J., Liu, R.-M., Bernard, K., Thannickal, V. J., & Liu, G. (2015) · American Journal of Respiratory and Critical Care Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisCancer, Hypoxia, and Metabolism

Cited by 582

Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction

Huang, X., Yang, N., Fiore, V. F., Barker, T. H., Sun, Y., Morris, S. W., Ding, Q., Thannickal, V. J., & Zhou, Y. (2012) · American Journal of Respiratory Cell and Molecular Biology

Cellular Mechanics and InteractionsInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 530

Airway remodeling in asthma

Hough, K. P., Curtiss, M. L., Blain, T. J., Liu, R.-M., Trevor, J., Deshane, J. S., & Thannickal, V. J. (2020) · Frontiers in Medicine

Asthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 432

Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis

Larson-Casey, J. L., Deshane, J. S., Ryan, A. J., Thannickal, V. J., & Carter, A. B. (2016) · Immunity

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisAutophagy in Disease and Therapy

Cited by 428

Prostaglandin E2 Inhibits Fibroblast to Myofibroblast Transition via E. Prostanoid Receptor 2 Signaling and Cyclic Adenosine Monophosphate Elevation

Kolodsick, J. E., Peters-Golden, M., Larios, J., Toews, G. B., Thannickal, V. J., & Moore, B. B. (2003) · American Journal of Respiratory Cell and Molecular Biology

Inflammatory mediators and NSAID effectsInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 294

The natural history of progressive fibrosing interstitial lung diseases

Brown, K. K., Martinez, F. J., Walsh, S. L. F., Thannickal, V. J., Prasse, A., Schlenker-Herceg, R., Goeldner, R.-G., Clerisme-Beaty, E., Tetzlaff, K., Cottin, V., et al. (2020) · European Respiratory Journal

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational and environmental lung diseases

Cited by 293

miR-125a-5p Regulates Differential Activation of Macrophages and Inflammation

Banerjee, S., Cui, H., Xie, N., Tan, Z., Yang, S., Icyuz, M., Thannickal, V. J., Abraham, E., & Liu, G. (2013) · Journal of Biological Chemistry

MicroRNA in disease regulationImmune cells in cancer

Cited by 258

Activation of the Pro-survival Phosphatidylinositol 3-Kinase/AKT Pathway by Transforming Growth Factor-β1 in Mesenchymal Cells Is Mediated by p38 MAPK-dependent Induction of an Autocrine Growth Factor

Horowitz, J. C., Lee, D. Y., Waghray, M., Keshamouni, V. G., Thomas, P. E., Zhang, H., Cui, Z., & Thannickal, V. J. (2004) · Journal of Biological Chemistry

TGF-β signaling in diseasesProtein Kinase Regulation and GTPase Signaling

Cited by 239

Novel mechanisms for the antifibrotic action of nintedanib

Rangarajan, S., Kurundkar, A., Kurundkar, D., Bernard, K., Sanders, Y. Y., Ding, Q., Antony, V. B., Zhang, J., Zmijewski, J., & Thannickal, V. J. (2016) · American Journal of Respiratory Cell and Molecular Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTGF-β signaling in diseases

Cited by 238

Serpine 1 induces alveolar type II cell senescence through activating p53‐p21‐Rb pathway in fibrotic lung disease

Jiang, C., Liu, G., Luckhardt, T., Antony, V., Zhou, Y., Carter, A. B., Thannickal, V. J., & Liu, R. (2017) · Aging Cell

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTelomeres, Telomerase, and Senescence

Cited by 234

Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice

Sanders, Y. Y., Hagood, J. S., Liu, H., Zhang, W., Ambalavanan, N., & Thannickal, V. J. (2014) · European Respiratory Journal

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisPulmonary Hypertension Research and Treatments

Cited by 167

Prostaglandin E 2 induces fibroblast apoptosis by modulating multiple survival pathways

Huang, S. K., White, E. S., Wettlaufer, S. H., Grifka, H., Hogaboam, C. M., Thannickal, V. J., Horowitz, J. C., & Peters-Golden, M. (2009) · The FASEB Journal

Inflammatory mediators and NSAID effectsInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 147

Histone Modifications in Senescence-Associated Resistance to Apoptosis by Oxidative Stress

Sanders, Y. Y., Liu, H., Zhang, X., Hecker, L., Bernard, K., Desai, L., Liu, G., & Thannickal, V. J. (2013) · Redox Biology

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 138

miR-27a regulates inflammatory response of macrophages by targeting IL-10

Xie, N., Cui, H., Banerjee, S., Tan, Z., Salomao, R., Fu, M., Abraham, E., Thannickal, V. J., & Liu, G. (2014) · The Journal of Immunology

MicroRNA in disease regulationImmune Response and Inflammation

Cited by 128

Oxygen in the evolution of complex life and the price we pay

Thannickal, V. J. (2009) · American Journal of Respiratory Cell and Molecular Biology

Redox biology and oxidative stressPhysiological and biochemical adaptations

Cited by 116

miR-34a Inhibits Lung Fibrosis by Inducing Lung Fibroblast Senescence

Cui, H., Ge, J., Xie, N., Banerjee, S., Zhou, Y., Antony, V. B., Thannickal, V. J., & Liu, G. (2017) · American Journal of Respiratory Cell and Molecular Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisMicroRNA in disease regulation

Cited by 104

Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts

Bai, L., Bernard, K., Tang, X., Hu, M., Horowitz, J. C., Thannickal, V. J., & Sanders, Y. Y. (2019) · American Journal of Respiratory Cell and Molecular Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisEpigenetics and DNA Methylation

Cited by 88

Autoimmunity to vimentin is associated with outcomes of patients with idiopathic pulmonary fibrosis

Li, F. J., Surolia, R., Li, H., Wang, Z., Kulkarni, T., Liu, G., de Andrade, J. A., Kass, D. J., Thannickal, V. J., Duncan, S. R., et al. (2017) · The Journal of Immunology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisSystemic Sclerosis and Related Diseases

Cited by 85

miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions

Cui, H., Ge, J., Xie, N., Banerjee, S., Zhou, Y., Liu, R.-M., Thannickal, V. J., & Liu, G. (2017) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisMicroRNA in disease regulation

Cited by 66