Rebeck, G. William

Cerebrospinal fluid levels of amyloid β‐protein in alzheimer's disease: Inverse correlation with severity of dementia and effect of apolipoprotein e genotype

Nitsch, R. M., Rebeck, G. W., Deng, M., Richardson, U. I., Tennis, M., Schenk, D. B., Vigo‐Pelfrey, C., Lieberburg, I., Wurtman, R. J., Hyman, B. T., et al. (1995) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 113

Multiple pathways of apolipoprotein E signaling in primary neurons

Hoe, H., Harris, D. C., & Rebeck, G. W. (2005) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 111

The effects of ABCA1 on cholesterol efflux and Aβ levels in vitro and in vivo

Burns, M. P., Vardanian, L., Pajoohesh‐Ganji, A., Wang, L., Cooper, M., Harris, D. C., Duff, K., & Rebeck, G. W. (2006) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsCholesterol and Lipid Metabolism

Cited by 106

Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid β-peptide deposition in homozygous APP V717F transgenic mice

Irizarry, M. C., Cheung, B. S., Rebeck, G. W., Paul, S. M., Bales, K. R., & Hyman, B. T. (2000) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 93

The Metalloprotease Inhibitor TIMP-3 Regulates Amyloid Precursor Protein and Apolipoprotein E Receptor Proteolysis

Hoe, H.-S., Cooper, M. J., Burns, M. P., Lewis, P. A., van der Brug, M., Chakraborty, G., Cartagena, C. M., Pak, D. T. S., Cookson, M. R., & Rebeck, G. W. (2007) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsProtease and Inhibitor Mechanisms

Cited by 90

Endocytic disturbances distinguish among subtypes of alzheimer's disease and related disorders

Cataldo, A., Rebeck, G. W., Ghetti, B., Hulette, C., Lippa, C., Van Broeckhoven, C., Van Duijn, C., Cras, P., Bogdanovic, N., Bird, T., et al. (2001) · Annals of Neurology

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 90

Apolipoprotein E modulates γ‐secretase cleavage of the amyloid precursor protein

Irizarry, M. C., Deng, A., Lleo, A., Berezovska, O., Von Arnim, C. A. F., Martin‐Rehrmann, M., Manelli, A., LaDu, M. J., Hyman, B. T., & Rebeck, G. W. (2004) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 89

Apolipoprotein E and Alzheimer's disease: the protective effects of ApoE2 and E3

Rebeck, G. W., Kindy, M., & LaDu, M. J. (2002) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 89

Regulation of ApoE receptor proteolysis by ligand binding

Hoe, H.-S., & Rebeck, G. W. (2005) · Molecular Brain Research

Alzheimer's disease research and treatmentsNeurogenesis and neuroplasticity mechanisms

Cited by 85

APOE2 is associated with longevity independent of Alzheimer’s disease

Shinohara, M., Kanekiyo, T., Tachibana, M., Kurti, A., Shinohara, M., Fu, Y., Zhao, J., Han, X., Sullivan, P. M., Rebeck, G. W., et al. (2020) · eLife

Genetics, Aging, and Longevity in Model OrganismsAlzheimer's disease research and treatments

Cited by 82

Apolipoprotein E Genotype Affects Size of ApoE Complexes in Cerebrospinal Fluid

Heinsinger, N. M., Gachechiladze, M. A., & Rebeck, G. W. (2016) · Journal of Neuropathology & Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 74

FE65 interaction with the ApoE receptor ApoEr2

Hoe, H.-S., Magill, L. A., Guenette, S., Fu, Z., Vicini, S., & Rebeck, G. W. (2006) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 69

Modulation of Aβ Deposition in APP Transgenic Mice by an Apolipoprotein E Null Background

IRIZARRY, M. C., REBECK, G. W., CHEUNG, B., BALES, K., PAUL, S. M., HOLZMAN, D., & HYMAN, B. T. (2000) · Annals of the New York Academy of Sciences

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 66

The generation and function of soluble apoE receptors in the CNS

Rebeck, G. W., LaDu, M. J., Estus, S., Bu, G., & Weeber, E. J. (2006) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 66

APOE ε3/ε4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer’s disease diagnosis

Fukumoto, H., Ingelsson, M., Gårevik, N., Wahlund, L.-O., Nukina, N., Yaguchi, Y., Shibata, M., Hyman, B. T., Rebeck, G. W., & Irizarry, M. C. (2003) · Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 63

Modulation of ABCA1 by an LXR Agonist Reduces Beta-Amyloid Levels and Improves Outcome after Traumatic Brain Injury

Loane, D. J., Washington, P. M., Vardanian, L., Pocivavsek, A., Hoe, H.-S., Duff, K. E., Cernak, I., Rebeck, G. W., Faden, A. I., & Burns, M. P. (2011) · Journal of Neurotrauma

Traumatic Brain Injury and Neurovascular DisturbancesAlzheimer's disease research and treatments

Cited by 57

Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4

Stephenson, R. A., Sepulveda, J., Johnson, K. R., Lita, A., Gopalakrishnan, J., Acri, D. J., Beilina, A., Cheng, L., Yang, L. G., Root, J. T., et al. (2025) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsLipid metabolism and biosynthesis

Cited by 55

APOE genotype affects the pre‐synaptic compartment of glutamatergic nerve terminals

Dumanis, S. B., DiBattista, A. M., Miessau, M., Moussa, C. E. H., & Rebeck, G. W. (2013) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 55

Metabolic disturbances of a high-fat diet are dependent on APOE genotype and sex.

Jones, N. S., Watson, K. Q., & Rebeck, G. W. (2019) · eneuro

Alzheimer's disease research and treatmentsDiet, Metabolism, and Disease

Cited by 54

Age-related loss of noradrenergic neurons in the brains of triple transgenic mice

Manaye, K. F., Mouton, P. R., Xu, G., Drew, A., Lei, D.-L., Sharma, Y., Rebeck, G. W., & Turner, S. (2013) · AGE

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 54

O-glycosylation on cerebrospinal fluid and plasma apolipoprotein E differs in the lipid-binding domain

Flowers, S. A., Grant, O. C., Woods, R. J., & Rebeck, G. W. (2020) · Glycobiology

Glycosylation and Glycoproteins ResearchAlzheimer's disease research and treatments

Cited by 52

ApoE receptor 2 regulates synapse and dendritic spine formation

Dumanis, S. B., Cha, H.-J., Song, J. M., Trotter, J. H., Spitzer, M., Lee, J.-Y., Weeber, E. J., Turner, R. S., Pak, D. T. S., Rebeck, G. W., et al. (2011) · PLoS ONE

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 45

Apolipoprotein E decreases tau kinases and phospho-tau levels in primary neurons.

Hoe, H.-S., Freeman, J., & Rebeck, G. W. (2006) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 45

Extracellular Proteolysis of Apolipoprotein E (apoE) by Secreted Serine Neuronal Protease

Tamboli, I. Y., Heo, D., & Rebeck, G. W. (2014) · PLoS ONE

Alzheimer's disease research and treatmentsProtease and Inhibitor Mechanisms

Cited by 35