Rotimi, Charles N.

A global reference for human genetic variation

The 1000 Genomes Project Consortium, authors, C., Auton, A., Abecasis, G. R., Steering committee, Altshuler, D. M., Durbin, R. M., Abecasis, G. R., Bentley, D. R., Chakravarti, A., et al. (2015) · Nature

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 18,247

Finding the missing heritability of complex diseases

Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J., McCarthy, M. I., Ramos, E. M., Cardon, L. R., Chakravarti, A., et al. (2009) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 8,336

The Structure of Haplotype Blocks in the Human Genome

Gabriel, S. B., Schaffner, S. F., Nguyen, H., Moore, J. M., Roy, J., Blumenstiel, B., Higgins, J., DeFelice, M., Lochner, A., Faggart, M., et al. (2002) · Science

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 5,863

Replicating genotype–phenotype associations

NCI-NHGRI Working Group on Replication in Association Studies, Chanock, S. J., Manolio, T., Boehnke, M., Boerwinkle, E., Hunter, D. J., Thomas, G., Hirschhorn, J. N., Abecasis, G., Altshuler, D., et al. (2007) · Nature

Genetic Associations and EpidemiologyMeta-analysis and systematic reviews

Cited by 1,352

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

Steinthorsdottir, V., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Jonsdottir, T., Walters, G. B., Styrkarsdottir, U., Gretarsdottir, S., Emilsson, V., Ghosh, S., et al. (2007) · Nature Genetics

Genetic Associations and EpidemiologyPancreatic function and diabetes

Cited by 1,072

The power of genetic diversity in genome-wide association studies of lipids

Graham, S. E., Clarke, S. L., Wu, K.-H. H., Kanoni, S., Zajac, G. J. M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T. W., et al. (2021) · Nature

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 972

Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes

Gudmundsson, J., Sulem, P., Steinthorsdottir, V., Bergthorsson, J. T., Thorleifsson, G., Manolescu, A., Rafnar, T., Gudbjartsson, D., Agnarsson, B. A., Baker, A., et al. (2007) · Nature Genetics

Genetic Associations and EpidemiologyProstate Cancer Treatment and Research

Cited by 723

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rüeger, S., Speidel, L., Kim, Y. J., et al. (2022) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 704

A brief history of human disease genetics

Claussnitzer, M., Cho, J. H., Collins, R., Cox, N. J., Dermitzakis, E. T., Hurles, M. E., Kathiresan, S., Kenny, E. E., Lindgren, C. M., MacArthur, D. G., et al. (2020) · Nature

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 697

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., et al. (2024) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 606

Enabling the genomic revolution in Africa

The H3Africa Consortium, Matovu, E., Bucheton, B., Chisi, J., Enyaru, J., Hertz-Fowler, C., Koffi, M., Macleod, A., Mumba, D., Sidibe, I., et al. (2014) · Science

Genetics, Bioinformatics, and Biomedical ResearchBiotechnology and Related Fields

Cited by 519

Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps

Polygenic Risk Score Task Force of the International Common Disease Alliance, Adeyemo, A., Balaconis, M. K., Darnes, D. R., Fatumo, S., Granados Moreno, P., Hodonsky, C. J., Inouye, M., Kanai, M., Kato, K., et al. (2021) · Nature Medicine

Genetic Associations and EpidemiologyRace, Genetics, and Society

Cited by 413

Diversity and inclusion in genomic research: why the uneven progress?

Bentley, A. R., Callier, S., & Rotimi, C. N. (2017) · Journal of Community Genetics

Race, Genetics, and SocietyEthics in Clinical Research

Cited by 357

Abdominal Adiposity and Clustering of Multiple Metabolic Syndrome in White, Black and Hispanic Americans

Okosun, I. S., Liao, Y., Rotimi, C. N., Prewitt, T. E., & Cooper, R. S. (2000) · Annals of Epidemiology

Diabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic Diseases

Cited by 193

Conceptualizing human variation

Keita, S. O. Y., Kittles, R. A., Royal, C. D. M., Bonney, G. E., Furbert-Harris, P., Dunston, G. M., & Rotimi, C. N. (2004) · Nature Genetics

Race, Genetics, and SocietyForensic and Genetic Research

Cited by 166

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

Rusu, V., Hoch, E., Mercader, J. M., Tenen, D. E., Gymrek, M., Hartigan, C. R., DeRan, M., von Grotthuss, M., Fontanillas, P., Spooner, A., et al. (2017) · Cell

Genetic Associations and EpidemiologyMetabolism, Diabetes, and Cancer

Cited by 152

Whole-genome-sequence-based haplotypes reveal single origin of the sickle allele during the Holocene wet phase

Shriner, D., & Rotimi, C. N. (2018) · The American Journal of Human Genetics

Hemoglobinopathies and Related DisordersForensic and Genetic Research

Cited by 118

Transferability and Fine-Mapping of Genome-Wide Associated Loci for Adult Height across Human Populations

Shriner, D., Adeyemo, A., Gerry, N. P., Herbert, A., Chen, G., Doumatey, A., Huang, H., Zhou, J., Christman, M. F., & Rotimi, C. N. (2009) · PLoS ONE

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 56

A multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

Sung, Y. J., de las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., et al. (2019) · Human Molecular Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 43