Huffnagle, Gary B.

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

Theriot, C. M., Koenigsknecht, M. J., Carlson, P. E., Hatton, G. E., Nelson, A. M., Li, B., Huffnagle, G. B., Z. Li, J., & Young, V. B. (2014) · Nature Communications

Clostridium difficile and Clostridium perfringens researchGut microbiota and health

Cited by 974

Analysis of the lung microbiome in the “healthy” smoker and in COPD.

Erb-Downward, J. R., Thompson, D. L., Han, M. K., Freeman, C. M., McCloskey, L., Schmidt, L. A., Young, V. B., Toews, G. B., Curtis, J. L., Sundaram, B., et al. (2011) · PLoS ONE

Chronic Obstructive Pulmonary Disease (COPD) ResearchOral microbiology and periodontitis research

Cited by 973

The Microbiome and the Respiratory Tract

Dickson, R. P., Erb-Downward, J. R., Martinez, F. J., & Huffnagle, G. B. (2016) · Annual Review of Physiology

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 953

Analysis of the Upper Respiratory Tract Microbiotas as the Source of the Lung and Gastric Microbiotas in Healthy Individuals

Bassis, C. M., Erb-Downward, J. R., Dickson, R. P., Freeman, C. M., Schmidt, T. M., Young, V. B., Beck, J. M., Curtis, J. L., & Huffnagle, G. B. (2015) · mBio

Oral microbiology and periodontitis researchGut microbiota and health

Cited by 839

Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome

Dickson, R. P., Singer, B. H., Newstead, M. W., Falkowski, N. R., Erb-Downward, J. R., Standiford, T. J., & Huffnagle, G. B. (2016) · Nature Microbiology

Sepsis Diagnosis and TreatmentGut microbiota and health

Cited by 724

Spatial Variation in the Healthy Human Lung Microbiome and the Adapted Island Model of Lung Biogeography

Dickson, R. P., Erb-Downward, J. R., Freeman, C. M., McCloskey, L., Beck, J. M., Huffnagle, G. B., & Curtis, J. L. (2015) · Annals of the American Thoracic Society

Gut microbiota and healthChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 567

Bacterial topography of the healthy human lower respiratory tract

Dickson, R. P., Erb-Downward, J. R., Freeman, C. M., McCloskey, L., Falkowski, N. R., Huffnagle, G. B., & Curtis, J. L. (2017) · mBio

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 548

The respiratory tract microbiome and lung inflammation: a two-way street.

Huffnagle, G. B., Dickson, R. P., & Lukacs, N. W. (2017) · Mucosal Immunology

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 535

The role of the microbiome in exacerbations of chronic lung diseases

Dickson, R. P., Martinez, F. J., & Huffnagle, G. B. (2014) · The Lancet

Chronic Obstructive Pulmonary Disease (COPD) ResearchAsthma and respiratory diseases

Cited by 495

Application of a Neutral Community Model To Assess Structuring of the Human Lung Microbiome

Venkataraman, A., Bassis, C. M., Beck, J. M., Young, V. B., Curtis, J. L., Huffnagle, G. B., & Schmidt, T. M. (2015) · mBio

Microbial Community Ecology and PhysiologyGut microbiota and health

Cited by 428

Towards an ecology of the lung: new conceptual models of pulmonary microbiology and pneumonia pathogenesis

Dickson, R. P., Erb-Downward, J. R., & Huffnagle, G. B. (2014) · The Lancet Respiratory Medicine

Pneumonia and Respiratory InfectionsGut microbiota and health

Cited by 371

Role of Antibiotics and Fungal Microbiota in Driving Pulmonary Allergic Responses

Noverr, M. C., Noggle, R. M., Toews, G. B., & Huffnagle, G. B. (2004) · Infection and Immunity

Asthma and respiratory diseasesGut microbiota and health

Cited by 330

The microbiome in respiratory medicine: current challenges and future perspectives

Faner, R., Sibila, O., Agustí, A., Bernasconi, E., Chalmers, J. D., Huffnagle, G. B., Manichanh, C., Molyneaux, P. L., Paredes, R., Pérez Brocal, V., et al. (2017) · European Respiratory Journal

Gut microbiota and healthChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 247

Analysis of culture-dependent versus culture-independent techniques for identification of bacteria in clinically obtained bronchoalveolar lavage fluid

Dickson, R. P., Erb-Downward, J. R., Prescott, H. C., Martinez, F. J., Curtis, J. L., Lama, V. N., & Huffnagle, G. B. (2014) · Journal of Clinical Microbiology

Bacterial Identification and Susceptibility TestingGenomics and Phylogenetic Studies

Cited by 176

Stress-induced corticotropin-releasing hormone-mediated NLRP6 inflammasome inhibition and transmissible enteritis in mice

Sun, Y., Zhang, M., Chen, C., Gillilland, M., Sun, X., El–Zaatari, M., Huffnagle, G. B., Young, V. B., Zhang, J., Hong, S., et al. (2013) · Gastroenterology

Inflammasome and immune disordersGastrointestinal motility and disorders

Cited by 157

Microbes Are Associated with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis

Huang, Y., Ma, S.-F., Espindola, M. S., Vij, R., Oldham, J. M., Huffnagle, G. B., Erb-Downward, J. R., Flaherty, K. R., Moore, B. B., White, E. S., et al. (2017) · American Journal of Respiratory and Critical Care Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational and environmental lung diseases

Cited by 142

Modulation of post-antibiotic bacterial community reassembly and host response by Candida albicans

Erb Downward, J. R., Falkowski, N. R., Mason, K. L., Muraglia, R., & Huffnagle, G. B. (2013) · Scientific Reports

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 136

Role of PLB1 in Pulmonary Inflammation and Cryptococcal Eicosanoid Production

Noverr, M. C., Cox, G. M., Perfect, J. R., & Huffnagle, G. B. (2003) · Infection and Immunity

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 133

Accumulation of CD11b+ Lung Dendritic Cells in Response to Fungal Infection Results from the CCR2-Mediated Recruitment and Differentiation of Ly-6Chigh Monocytes

Osterholzer, J. J., Chen, G.-H., Olszewski, M. A., Curtis, J. L., Huffnagle, G. B., & Toews, G. B. (2009) · The Journal of Immunology

Fungal Infections and StudiesImmunotherapy and Immune Responses

Cited by 121

CNLAC1 Is Required for Extrapulmonary Dissemination of Cryptococcus neoformans but Not Pulmonary Persistence

Noverr, M. C., Williamson, P. R., Fajardo, R. S., & Huffnagle, G. B. (2004) · Infection and Immunity

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 112

A tale of two sites: how inflammation can reshape the microbiomes of the gut and lungs

Scales, B. S., Dickson, R. P., & Huffnagle, G. B. (2016) · Journal of Leukocyte Biology

Gut microbiota and healthBacterial biofilms and quorum sensing

Cited by 109

The respiratory microbiome: an underappreciated player in the human response to inhaled pollutants?

Adar, S. D., Huffnagle, G. B., & Curtis, J. L. (2016) · Annals of Epidemiology

Air Quality and Health ImpactsIndoor Air Quality and Microbial Exposure

Cited by 88

Interleukin-17 Drives Pulmonary Eosinophilia following Repeated Exposure to Aspergillus fumigatus Conidia

Murdock, B. J., Falkowski, N. R., Shreiner, A. B., Sadighi Akha, A. A., McDonald, R. A., White, E. S., Toews, G. B., & Huffnagle, G. B. (2012) · Infection and Immunity

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 87

Responders and non-responders to probiotic interventions: How can we improve the odds?

Reid, G., Gaudier, E., Guarner, F., Huffnagle, G. B., Macklaim, J. M., Munoz, A. M., Martini, M., Ringel-Kulka, T., Sartor, B. R., Unal, R. R., et al. (2010) · Gut Microbes

Probiotics and Fermented FoodsGastrointestinal motility and disorders

Cited by 76