Rangachari, Manu

Bat3 promotes T cell responses and autoimmunity by repressing Tim-3-mediated cell death and exhaustion

Rangachari, M., Zhu, C., Sakuishi, K., Xiao, S., Karman, J., Chen, A., Angin, M., Wakeham, A., Greenfield, E. A., Sobel, R. A., et al. (2012) · Nature Medicine

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 394

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

Cronin, S. J. F., Seehus, C., Weidinger, A., Talbot, S., Reissig, S., Seifert, M., Pierson, Y., McNeill, E., Longhi, M. S., Turnes, B. L., et al. (2018) · Nature

T-cell and B-cell ImmunologyBiochemical and Molecular Research

Cited by 285

IL-1β enables CNS access to CCR2 hi monocytes and the generation of pathogenic cells through GM-CSF released by CNS endothelial cells

Paré, A., Mailhot, B., Lévesque, S. A., Juzwik, C., Ignatius Arokia Doss, P. M., Lécuyer, M.-A., Prat, A., Rangachari, M., Fournier, A., & Lacroix, S. (2018) · Proceedings of the National Academy of Sciences

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 94

Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion

Zhu, C., Dixon, K. O., Newcomer, K., Gu, G., Xiao, S., Zaghouani, S., Schramm, M. A., Wang, C., Zhang, H., Goto, K., et al. (2021) · Science Advances

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 40

Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity

Doss, P. M. I. A., Umair, M., Baillargeon, J., Fazazi, R., Fudge, N., Akbar, I., Yeola, A. P., Williams, J. B., Leclercq, M., Joly-Beauparlant, C., et al. (2021) · Cell Reports

Multiple Sclerosis Research StudiesPsoriasis: Treatment and Pathogenesis

Cited by 39

Myelin-reactive B cells exacerbate CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner

Fazazi, M. R., Doss, P. M. I. A., Pereira, R., Fudge, N., Regmi, A., Joly-Beauparlant, C., Akbar, I., Yeola, A. P., Mailhot, B., Baillargeon, J., et al. (2024) · Nature Communications

Multiple Sclerosis Research StudiesT-cell and B-cell Immunology

Cited by 21

Sex chromosomes and sex hormones differently shape microglial properties during normal physiological conditions in the adult mouse hippocampus

Bobotis, B. C., Khakpour, M., Braniff, O., de Andrade, E. G., Gargus, M., Allen, M., Carrier, M., Baillargeon, J., Rangachari, M., & Tremblay, M.-È. (2025) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsSex and Gender in Healthcare

Cited by 17