Lancaster, Madeline A.

Cerebral organoids model human brain development and microcephaly

Lancaster, M. A., Renner, M., Martin, C.-A., Wenzel, D., Bicknell, L. S., Hurles, M. E., Homfray, T., Penninger, J. M., Jackson, A. P., & Knoblich, J. A. (2013) · Nature

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 5,372

Organogenesis in a dish: Modeling development and disease using organoid technologies

Lancaster, M. A., & Knoblich, J. A. (2014) · Science

Pluripotent Stem Cells Research3D Printing in Biomedical Research

Cited by 2,931

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

Camp, J. G., Badsha, F., Florio, M., Kanton, S., Gerber, T., Wilsch-Bräuninger, M., Lewitus, E., Sykes, A., Hevers, W., Lancaster, M., et al. (2015) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsSingle-cell and spatial transcriptomics

Cited by 1,130

Guided self-organization and cortical plate formation in human brain organoids

Lancaster, M. A., Corsini, N. S., Wolfinger, S., Gustafson, E. H., Phillips, A. W., Burkard, T. R., Otani, T., Livesey, F. J., & Knoblich, J. A. (2017) · Nature Biotechnology

Neurogenesis and neuroplasticity mechanisms3D Printing in Biomedical Research

Cited by 783

Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output

Giandomenico, S. L., Mierau, S. B., Gibbons, G. M., Wenger, L. M. D., Masullo, L., Sit, T., Sutcliffe, M., Boulanger, J., Tripodi, M., Derivery, E., et al. (2019) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 651

Induction of Expansion and Folding in Human Cerebral Organoids

Li, Y., Muffat, J., Omer, A., Bosch, I., Lancaster, M. A., Sur, M., Gehrke, L., Knoblich, J. A., & Jaenisch, R. (2017) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsFetal and Pediatric Neurological Disorders

Cited by 436

Self‐organized developmental patterning and differentiation in cerebral organoids

Renner, M., Lancaster, M. A., Bian, S., Choi, H., Ku, T., Peer, A., Chung, K., & Knoblich, J. A. (2017) · The EMBO Journal

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 389

Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain

Luo, C., Lancaster, M. A., Castanon, R., Nery, J. R., Knoblich, J. A., & Ecker, J. R. (2016) · Cell Reports

Epigenetics and DNA MethylationPluripotent Stem Cells Research

Cited by 370

Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids

Marsee, A., Roos, F. J. M., Verstegen, M. M. A., Marsee, A., Roos, F., Verstegen, M., Clevers, H., Vallier, L., Takebe, T., Huch, M., et al. (2021) · Cell Stem Cell

3D Printing in Biomedical ResearchPancreatic function and diabetes

Cited by 310

Subcellular spatial regulation of canonical Wnt signalling at the primary cilium

Lancaster, M. A., Schroth, J., & Gleeson, J. G. (2011) · Nature Cell Biology

Genetic and Kidney Cyst DiseasesWnt/β-catenin signaling in development and cancer

Cited by 267

Impaired Wnt–β-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy

Lancaster, M. A., Louie, C. M., Silhavy, J. L., Sintasath, L., DeCambre, M., Nigam, S. K., Willert, K., & Gleeson, J. G. (2009) · Nature Medicine

Genetic and Kidney Cyst DiseasesWnt/β-catenin signaling in development and cancer

Cited by 175

Genetic correlates of phenotypic heterogeneity in autism

Warrier, V., Zhang, X., Reed, P., Havdahl, A., Moore, T. M., Cliquet, F., Leblond, C. S., Rolland, T., Rosengren, A., LEAP, E.-A., et al. (2022) · Nature Genetics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 152

ISSCR standards for the use of human stem cells in basic research

Ludwig, T. E., Andrews, P. W., Barbaric, I., Benvenisty, N., Bhattacharyya, A., Crook, J. M., Daheron, L. M., Draper, J. S., Healy, L. E., Huch, M., et al. (2023) · Stem Cell Reports

Pluripotent Stem Cells ResearchBiomedical Ethics and Regulation

Cited by 126

Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoids

Hoffmann, P. C., Giandomenico, S. L., Ganeva, I., Wozny, M. R., Sutcliffe, M., Lancaster, M. A., & Kukulski, W. (2021) · eLife

Advanced Electron Microscopy Techniques and ApplicationsAxon Guidance and Neuronal Signaling

Cited by 53