Brown, Andrew J.

The DNA sequence of the human X chromosome

Ross, M. T., Grafham, D. V., Coffey, A. J., Scherer, S., McLay, K., Muzny, D., Platzer, M., Howell, G. R., Burrows, C., Bird, C. P., et al. (2005) · Nature

Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesChromosomal and Genetic Variations

Cited by 1,129

Cholesterol Addition to ER Membranes Alters Conformation of SCAP, the SREBP Escort Protein that Regulates Cholesterol Metabolism

Brown, A. J., Sun, L., Feramisco, J. D., Brown, M. S., & Goldstein, J. L. (2002) · Molecular Cell

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 417

Controlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)

Sharpe, L. J., & Brown, A. J. (2013) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 382

Dietary polyunsaturated fats of the W-6 and W-3 series reduce postprandial lipoprotein levels. Chronic and acute effects of fat saturation on postprandial lipoprotein metabolism.

Weintraub, M. S., Zechner, R., Brown, A., Eisenberg, S., & Breslow, J. L. (1988) · Journal of Clinical Investigation

Fatty Acid Research and HealthLipid metabolism and disorders

Cited by 331

Cholesterol-Dependent Degradation of Squalene Monooxygenase, a Control Point in Cholesterol Synthesis beyond HMG-CoA Reductase

Gill, S., Stevenson, J., Kristiana, I., & Brown, A. J. (2011) · Cell Metabolism

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 304

Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models

Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., et al. (2023) · Nature Biotechnology

Bioinformatics and Genomic NetworksComputational Drug Discovery Methods

Cited by 111

A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols

Yan, R., Cao, P., Song, W., Qian, H., Du, X., Coates, H. W., Zhao, X., Li, Y., Gao, S., Gong, X., et al. (2021) · Science

Cholesterol and Lipid MetabolismLipid Membrane Structure and Behavior

Cited by 100

Moderate fish oil intake improves lipemic response to a standard fat meal: A study in 25 healthy men

Brown, A. J., & Roberts, D. C. (1991) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology

Fatty Acid Research and HealthLipid metabolism and disorders

Cited by 59

A MARCH6 and IDOL E3 Ubiquitin Ligase Circuit Uncouples Cholesterol Synthesis from Lipoprotein Uptake in Hepatocytes

Loregger, A., Cook, E. C. L., Nelson, J. K., Moeton, M., Sharpe, L. J., Engberg, S., Karimova, M., Lambert, G., Brown, A. J., & Zelcer, N. (2016) · Molecular and Cellular Biology

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 48

What dictates the accumulation of desmosterol in the developing brain?

Jansen, M., Wang, W., Greco, D., Bellenchi, G. C., di Porzio, U., Brown, A. J., & Ikonen, E. (2013) · The FASEB Journal

Cholesterol and Lipid MetabolismLipid Membrane Structure and Behavior

Cited by 42