Yang, Chun

Nervous system involvement after infection with COVID-19 and other coronaviruses

Wu, Y., Xu, X., Chen, Z., Duan, J., Hashimoto, K., Yang, L., Liu, C., & Yang, C. (2020) · Brain, Behavior, and Immunity

Long-Term Effects of COVID-19Infectious Encephalopathies and Encephalitis

Cited by 2,046

Regulation of learning and memory by meningeal immunity: a key role for IL-4

Derecki, N. C., Cardani, A. N., Yang, C. H., Quinnies, K. M., Crihfield, A., Lynch, K. R., & Kipnis, J. (2010) · Journal of Experimental Medicine

Neuroinflammation and Neurodegeneration MechanismsT-cell and B-cell Immunology

Cited by 800

R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects

Yang, C., Shirayama, Y., Zhang, J.-C., Ren, Q., Yao, W., Ma, M., Dong, C., & Hashimoto, K. (2015) · Translational Psychiatry

Treatment of Major DepressionTryptophan and brain disorders

Cited by 605

Ketamine-induced antidepressant effects are associated with AMPA receptors-mediated upregulation of mTOR and BDNF in rat hippocampus and prefrontal cortex

Zhou, W., Wang, N., Yang, C., Li, X.-M., Zhou, Z.-Q., & Yang, J.-J. (2014) · European Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 390

Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction

Jeon, M.-S., Atfield, A., Venuprasad, K., Krawczyk, C., Sarao, R., Elly, C., Yang, C., Arya, S., Bachmaier, K., Su, L., et al. (2004) · Immunity

T-cell and B-cell ImmunologyImmune Response and Inflammation

Cited by 348

Antidepressant Effects of TrkB Ligands on Depression-Like Behavior and Dendritic Changes in Mice After Inflammation

Zhang, J.-C., Wu, J., Fujita, Y., Yao, W., Ren, Q., Yang, C., Li, S.-X., Shirayama, Y., & Hashimoto, K. (2015) · International Journal of Neuropsychopharmacology

Treatment of Major DepressionTryptophan and brain disorders

Cited by 289

Microglial ERK-NRBP1-CREB-BDNF Signaling in Sustained Antidepressant Actions of (R)-Ketamine

Yao, W., Cao, Q., Luo, S., He, L., Yang, C., Chen, J., Qi, Q., Hashimoto, K., & Zhang, J.-C. (2022) · Molecular Psychiatry

Treatment of Major DepressionTryptophan and brain disorders

Cited by 216

Molecular and cellular mechanisms underlying the antidepressant effects of ketamine enantiomers and its metabolites

Yang, C., Yang, J., Luo, A., & Hashimoto, K. (2019) · Translational Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 190

Comparison of ketamine, 7,8-dihydroxyflavone, and ANA-12 antidepressant effects in the social defeat stress model of depression

Zhang, J.-C., Yao, W., Dong, C., Yang, C., Ren, Q., Ma, M., Han, M., & Hashimoto, K. (2015) · Psychopharmacology

Treatment of Major DepressionTryptophan and brain disorders

Cited by 183

Key role of gut microbiota in anhedonia-like phenotype in rodents with neuropathic pain

Yang, C., Fang, X., Zhan, G., Huang, N., Li, S., Bi, J., Jiang, R., Yang, L., Miao, L., Zhu, B., et al. (2019) · Translational Psychiatry

Gut microbiota and healthPain Mechanisms and Treatments

Cited by 176

Acute administration of ketamine in rats increases hippocampal BDNF and mTOR levels during forced swimming test

Yang, C., Hu, Y.-M., Zhou, Z.-Q., Zhang, G.-F., & Yang, J.-J. (2013) · Upsala Journal of Medical Sciences

Treatment of Major DepressionTryptophan and brain disorders

Cited by 173

Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice

Yao, W., Zhang, J.-C., Ishima, T., Dong, C., Yang, C., Ren, Q., Ma, M., Han, M., Wu, J., Suganuma, H., et al. (2016) · Scientific Reports

Tryptophan and brain disordersGenomics, phytochemicals, and oxidative stress

Cited by 154

Alterations in brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain regions of a learned helplessness rat model and the antidepressant effects of a TrkB agonist and antagonist

Shirayama, Y., Yang, C., Zhang, J.-C., Ren, Q., Yao, W., & Hashimoto, K. (2015) · European Neuropsychopharmacology

Treatment of Major DepressionNerve injury and regeneration

Cited by 137

Essential role of microglial transforming growth factor-β1 in antidepressant actions of (R)-ketamine and the novel antidepressant TGF-β1

Zhang, K., Yang, C., Chang, L., Sakamoto, A., Suzuki, T., Fujita, Y., Qu, Y., Wang, S., Pu, Y., Tan, Y., et al. (2020) · Translational Psychiatry

Treatment of Major DepressionTryptophan and brain disorders

Cited by 119

(2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in mice

Yamaguchi, J.-I., Toki, H., Qu, Y., Yang, C., Koike, H., Hashimoto, K., Mizuno-Yasuhira, A., & Chaki, S. (2018) · Neuropsychopharmacology

Treatment of Major DepressionTryptophan and brain disorders

Cited by 105

Retracted: Regional Differences in Brain-Derived Neurotrophic Factor Levels and Dendritic Spine Density Confer Resilience to Inescapable Stress

Yang, C., Shirayama, Y., Zhang, J.-C., Ren, Q., & Hashimoto, K. (2015) · International Journal of Neuropsychopharmacology

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 103

Comparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depression

Yang, B., Zhang, J.-C., Han, M., Yao, W., Yang, C., Ren, Q., Ma, M., Chen, Q.-X., & Hashimoto, K. (2016) · Psychopharmacology

Treatment of Major DepressionTryptophan and brain disorders

Cited by 91

Loss of parvalbumin-immunoreactivity in mouse brain regions after repeated intermittent administration of esketamine, but not R-ketamine

Yang, C., Han, M., Zhang, J.-C., Ren, Q., & Hashimoto, K. (2016) · Psychiatry Research

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 91

Regional differences in dendritic spine density confer resilience to chronic social defeat stress

Qu, Y., Yang, C., Ren, Q., Ma, M., Dong, C., & Hashimoto, K. (2018) · Acta Neuropsychiatrica

Neuroscience and Neuropharmacology ResearchStress Responses and Cortisol

Cited by 68

Acute Increases in Plasma Mammalian Target of Rapamycin, Glycogen Synthase Kinase-3β, and Eukaryotic Elongation Factor 2 Phosphorylation After Ketamine Treatment in Three Depressed Patients

Yang, C., Zhou, Z.-Q., Gao, Z.-Q., Shi, J.-Y., & Yang, J.-J. (2013) · Biological Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 55

Downregulation of neuregulin 1-ErbB4 signaling in parvalbumin interneurons in the rat brain may contribute to the antidepressant properties of ketamine

Wang, N., Zhang, G.-F., Liu, X.-Y., Sun, H.-L., Wang, X.-M., Qiu, L.-L., Yang, C., & Yang, J.-J. (2014) · Journal of Molecular Neuroscience

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 41

Is (S)-norketamine an alternative antidepressant for esketamine?

Hashimoto, K., & Yang, C. (2019) · European Archives of Psychiatry and Clinical Neuroscience

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 37

PGC-1α–FNDC5–BDNF signaling pathway in skeletal muscle confers resilience to stress in mice subjected to chronic social defeat

Zhan, G., Huang, N., Li, S., Hua, D., Zhang, J., Fang, X., Yang, N., Luo, A., & Yang, C. (2018) · Psychopharmacology

Muscle Physiology and DisordersTreatment of Major Depression

Cited by 32

Tramadol Pretreatment Enhances Ketamine-Induced Antidepressant Effects and Increases Mammalian Target of Rapamycin in Rat Hippocampus and Prefrontal Cortex

Yang, C., Li, W.-Y., Yu, H.-Y., Gao, Z.-Q., Liu, X.-L., Zhou, Z.-Q., & Yang, J.-J. (2012) · Journal of Biomedicine and Biotechnology

Treatment of Major DepressionTryptophan and brain disorders

Cited by 29