Barker, Roger A.

RNA velocity of single cells

La Manno, G., Soldatov, R., Zeisel, A., Braun, E., Hochgerner, H., Petukhov, V., Lidschreiber, K., Kastriti, M. E., Lönnerberg, P., Furlan, A., et al. (2018) · Nature

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 4,118

Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines

Litvan, I., Goldman, J. G., Tröster, A. I., Schmand, B. A., Weintraub, D., Petersen, R. C., Mollenhauer, B., Adler, C. H., Marder, K., Williams‐Gray, C. H., et al. (2012) · Movement Disorders

Dementia and Cognitive Impairment ResearchParkinson's Disease Mechanisms and Treatments

Cited by 2,609

Molecular diversity of midbrain development in mouse, human, and stem cells

La Manno, G., Gyllborg, D., Codeluppi, S., Nishimura, K., Salto, C., Zeisel, A., Borm, L. E., Stott, S. R. W., Toledo, E. M., Villaescusa, J. C., et al. (2016) · Cell

Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms

Cited by 835

Targeting Huntingtin Expression in Patients with Huntington’s Disease

Tabrizi, S. J., Leavitt, B. R., Landwehrmeyer, G. B., Wild, E. J., Saft, C., Barker, R. A., Blair, N. F., Craufurd, D., Priller, J., Rickards, H., et al. (2019) · New England Journal of Medicine

Genetic Neurodegenerative DiseasesLysosomal Storage Disorders Research

Cited by 708

Cognitive impairments in early Parkinson's disease are accompanied by reductions in activity in frontostriatal neural circuitry

Lewis, S. J. G., Dove, A., Robbins, T. W., Barker, R. A., & Owen, A. M. (2003) · The Journal of Neuroscience

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 532

l-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson’s disease

Cools, R., Barker, R. A., Sahakian, B. J., & Robbins, T. W. (2003) · Neuropsychologia

Parkinson's Disease Mechanisms and TreatmentsNeural and Behavioral Psychology Studies

Cited by 516

Sleep and Circadian Rhythm Regulation in Early Parkinson Disease

Breen, D. P., Vuono, R., Nawarathna, U., Fisher, K., Shneerson, J. M., Reddy, A. B., & Barker, R. A. (2014) · JAMA Neurology

Circadian rhythm and melatoninParkinson's Disease Mechanisms and Treatments

Cited by 440

Excessive burden of lysosomal storage disorder gene variants in Parkinson’s disease

Robak, L. A., Jansen, I. E., van Rooij, J., Uitterlinden, A. G., Kraaij, R., Jankovic, J., Heutink, P., Shulman, J. M., International Parkinson’s Disease Genomics Consortium (IPDGC), Nalls, M. A., et al. (2017) · Brain

Lysosomal Storage Disorders ResearchParkinson's Disease Mechanisms and Treatments

Cited by 433

Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease

Morton, A. J., Wood, N. I., Hastings, M. H., Hurelbrink, C., Barker, R. A., & Maywood, E. S. (2005) · The Journal of Neuroscience

Circadian rhythm and melatoninSleep and Wakefulness Research

Cited by 403

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

Moss, D. J. H., Pardiñas, A. F., Langbehn, D., Lo, K., Leavitt, B. R., Roos, R., Durr, A., Mead, S., Coleman, A., Santos, R. D., et al. (2017) · The Lancet Neurology

Genetic Neurodegenerative DiseasesGenetic Associations and Epidemiology

Cited by 312

Cerebrovascular and blood–brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology

Drouin‐Ouellet, J., Sawiak, S. J., Cisbani, G., Lagacé, M., Kuan, W., Saint‐Pierre, M., Dury, R. J., Alata, W., St‐Amour, I., Mason, S. L., et al. (2015) · Annals of Neurology

Barrier Structure and Function StudiesGenetic Neurodegenerative Diseases

Cited by 288

The Cambridge Behavioural Inventory revised

Wear, H. J., Wedderburn, C. J., Mioshi, E., Williams-Gray, C. H., Mason, S. L., Barker, R. A., & Hodges, J. R. (2008) · Dementia & Neuropsychologia

Dementia and Cognitive Impairment ResearchHistorical and Modern Theater Studies

Cited by 225

New approaches for brain repair-from rescue to reprogramming

Barker, R. A., Götz, M., & Parmar, M. (2018) · Nature

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 214

Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: a multimodal imaging study

Politis, M., Pavese, N., Tai, Y. F., Kiferle, L., Mason, S. L., Brooks, D. J., Tabrizi, S. J., Barker, R. A., & Piccini, P. (2011) · Human Brain Mapping

Genetic Neurodegenerative DiseasesNeurological diseases and metabolism

Cited by 212

Using executive heterogeneity to explore the nature of working memory deficits in Parkinson’s disease

Lewis, S. J. G., Cools, R., Robbins, T. W., Dove, A., Barker, R. A., & Owen, A. M. (2003) · Neuropsychologia

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 201

Mutant huntingtin is present in neuronal grafts in huntington disease patients

Cicchetti, F., Lacroix, S., Cisbani, G., Vallières, N., Saint‐Pierre, M., St‐Amour, I., Tolouei, R., Skepper, J. N., Hauser, R. A., Mantovani, D., et al. (2014) · Annals of Neurology

Genetic Neurodegenerative DiseasesPrion Diseases and Protein Misfolding

Cited by 193

Cognitive Deficits and Psychosis in Parkinson???s Disease: A Review of Pathophysiology and Therapeutic Options

Williams-Gray, C. H., Foltynie, T., Lewis, S. J. G., & Barker, R. A. (2006) · CNS Drugs

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 147

A human embryonic limb cell atlas resolved in space and time

Zhang, B., He, P., Lawrence, J. E. G., Wang, S., Tuck, E., Williams, B. A., Roberts, K., Kleshchevnikov, V., Mamanova, L., Bolt, L., et al. (2024) · Nature

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 143

Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson’s disease

Liu, G., Peng, J., Liao, Z., Locascio, J. J., Corvol, J.-C., Zhu, F., Dong, X., Maple-Grødem, J., Campbell, M. C., Elbaz, A., et al. (2021) · Nature Genetics

Parkinson's Disease Mechanisms and TreatmentsGenetic Associations and Epidemiology

Cited by 127

Habitual versus goal-directed action control in Parkinson disease

de Wit, S., Barker, R. A., Dickinson, A. D., & Cools, R. (2011) · Journal of Cognitive Neuroscience

Neural and Behavioral Psychology StudiesParkinson's Disease Mechanisms and Treatments

Cited by 116

A prenatal skin atlas reveals immune regulation of human skin morphogenesis

Gopee, N. H., Winheim, E., Olabi, B., Admane, C., Foster, A. R., Huang, N., Botting, R. A., Torabi, F., Sumanaweera, D., Le, A. P., et al. (2024) · Nature

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 108

Task-Set Switching Deficits in Early-Stage Huntington's Disease: Implications for Basal Ganglia Function

Aron, A. R., Watkins, L., Sahakian, B. J., Monsell, S., Barker, R. A., & Robbins, T. W. (2003) · Journal of Cognitive Neuroscience

Neural and Behavioral Psychology StudiesGenetic Neurodegenerative Diseases

Cited by 106

GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain

Dar, G. H., Mendes, C. C., Kuan, W.-L., Speciale, A. A., Conceição, M., Görgens, A., Uliyakina, I., Lobo, M. J., Lim, W. F., EL Andaloussi, S., et al. (2021) · Nature Communications

Extracellular vesicles in diseaseRNA Interference and Gene Delivery

Cited by 100

WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis

Kaiser, K., Gyllborg, D., Procházka, J., Salašová, A., Kompaníková, P., Molina, F. L., Laguna-Goya, R., Radaszkiewicz, T., Harnoš, J., Procházková, M., et al. (2019) · Nature Communications

Wnt/β-catenin signaling in development and cancerCerebrospinal fluid and hydrocephalus

Cited by 87