Chi, Hongbo

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

Wang, R., Dillon, C. P., Shi, L. Z., Milasta, S., Carter, R., Finkelstein, D., McCormick, L. L., Fitzgerald, P., Chi, H., Munger, J., et al. (2011) · Immunity

Cancer, Hypoxia, and MetabolismT-cell and B-cell Immunology

Cited by 2,140

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

Shi, L. Z., Wang, R., Huang, G., Vogel, P., Neale, G., Green, D. R., & Chi, H. (2011) · Journal of Experimental Medicine

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 1,803

Regulation and function of mTOR signalling in T cell fate decisions

Chi, H. (2012) · Nature Reviews Immunology

PI3K/AKT/mTOR signaling in cancerT-cell and B-cell Immunology

Cited by 1,035

Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression

Bai, B., Wang, X., Li, Y., Chen, P.-C., Yu, K., Dey, K. K., Yarbro, J. M., Han, X., Lutz, B. M., Rao, S., et al. (2020) · Neuron

Alzheimer's disease research and treatmentsAdvanced Proteomics Techniques and Applications

Cited by 565

Helper T cell differentiation

Saravia, J., Chapman, N. M., & Chi, H. (2019) · Cellular & Molecular Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 489

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

Wei, J., Long, L., Yang, K., Guy, C., Shrestha, S., Chen, Z., Wu, C., Vogel, P., Neale, G., Green, D. R., et al. (2016) · Nature Immunology

T-cell and B-cell ImmunologyAutophagy in Disease and Therapy

Cited by 470

Receptor interacting protein kinase 2–mediated mitophagy regulates inflammasome activation during virus infection

Lupfer, C., Thomas, P. G., Anand, P. K., Vogel, P., Milasta, S., Martinez, J., Huang, G., Green, M., Kundu, M., Chi, H., et al. (2013) · Nature Immunology

Inflammasome and immune disordersAutophagy in Disease and Therapy

Cited by 384

Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation

Tan, H., Yang, K., Li, Y., Shaw, T. I., Wang, Y., Blanco, D. B., Wang, X., Cho, J.-H., Wang, H., Rankin, S., et al. (2017) · Immunity

Advanced Proteomics Techniques and ApplicationsT-cell and B-cell Immunology

Cited by 372

The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR

Liu, G., Burns, S., Huang, G., Boyd, K., Proia, R. L., Flavell, R. A., & Chi, H. (2009) · Nature Immunology

T-cell and B-cell ImmunologySphingolipid Metabolism and Signaling

Cited by 339

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity

Karmaus, P. W. F., Chen, X., Lim, S. A., Herrada, A. A., Nguyen, T.-L. M., Xu, B., Dhungana, Y., Rankin, S., Chen, W., Rosencrance, C., et al. (2019) · Nature

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 215

mTOR signaling at the crossroads of environmental signals and T‐cell fate decisions

Huang, H., Long, L., Zhou, P., Chapman, N. M., & Chi, H. (2020) · Immunological Reviews

PI3K/AKT/mTOR signaling in cancerT-cell and B-cell Immunology

Cited by 193

mTOR Signaling, Tregs and Immune Modulation

Chapman, N. M., & Chi, H. (2014) · Immunotherapy

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 148

Metabolic programs of T cell tissue residency empower tumour immunity

Reina-Campos, M., Heeg, M., Kennewick, K., Mathews, I. T., Galletti, G., Luna, V., Nguyen, Q., Huang, H., Milner, J. J., Hu, K. H., et al. (2023) · Nature

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 132

Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression

Bai, B., Wang, X., Li, Y., Chen, P.-C., Yu, K., Dey, K. K., Yarbro, J. M., Han, X., Lutz, B. M., Rao, S., et al. (2020) · Neuron

Alzheimer's disease research and treatmentsAdvanced Proteomics Techniques and Applications

Cited by 78

NetBID2 provides comprehensive hidden driver analysis

Dong, X., Ding, L., Thrasher, A., Wang, X., Liu, J., Pan, Q., Rash, J., Dhungana, Y., Yang, X., Risch, I., et al. (2023) · Nature Communications

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 37