Wysocka, Joanna

A unique chromatin signature uncovers early developmental enhancers in humans

Rada-Iglesias, A., Bajpai, R., Swigut, T., Brugmann, S. A., Flynn, R. A., & Wysocka, J. (2011) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 2,233

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

Tan, M., Luo, H., Lee, S., Jin, F., Yang, J. S., Montellier, E., Buchou, T., Cheng, Z., Rousseaux, S., Rajagopal, N., et al. (2011) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 1,902

Modification of Enhancer Chromatin: What, How, and Why?

Calo, E., & Wysocka, J. (2013) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 1,457

Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark

Ruthenburg, A. J., Allis, C. D., & Wysocka, J. (2007) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 1,147

Ever-Changing Landscapes: Transcriptional Enhancers in Development and Evolution

Long, H. K., Prescott, S. L., & Wysocka, J. (2016) · Cell

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 945

Reorganization of enhancer patterns in transition from naive to primed pluripotency

Buecker, C., Srinivasan, R., Wu, Z., Calo, E., Acampora, D., Faial, T., Simeone, A., Tan, M., Swigut, T., & Wysocka, J. (2014) · Cell Stem Cell

Pluripotent Stem Cells ResearchGenomics and Chromatin Dynamics

Cited by 507

Roles of transposable elements in the regulation of mammalian transcription

Fueyo, R., Judd, J., Feschotte, C., & Wysocka, J. (2022) · Nature Reviews Molecular Cell Biology

Chromosomal and Genetic VariationsGenomics and Chromatin Dynamics

Cited by 451

Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation

Dorighi, K. M., Swigut, T., Henriques, T., Bhanu, N. V., Scruggs, B. S., Nady, N., Still, C. D., Garcia, B. A., Adelman, K., & Wysocka, J. (2017) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 403

Transcription-coupled changes in nuclear mobility of mammalian cis-regulatory elements

Gu, B., Swigut, T., Spencley, A., Bauer, M. R., Chung, M., Meyer, T., & Wysocka, J. (2018) · Science

Genomics and Chromatin DynamicsCRISPR and Genetic Engineering

Cited by 363

H3K27 Demethylases, at Long Last

Swigut, T., & Wysocka, J. (2007) · Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 327

Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest

Rada-Iglesias, A., Bajpai, R., Prescott, S., Brugmann, S. A., Swigut, T., & Wysocka, J. (2012) · Cell stem cell

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 314

Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing

Mahmoudi, S., Mancini, E., Xu, L., Moore, A., Jahanbani, F., Hebestreit, K., Srinivasan, R., Li, X., Devarajan, K., Prélot, L., et al. (2019) · Nature

Wound Healing and TreatmentsPluripotent Stem Cells Research

Cited by 285

Genome-wide mapping of global-to-local genetic effects on human facial shape

Claes, P., Roosenboom, J., White, J. D., Swigut, T., Sero, D., Li, J., Lee, M. K., Zaidi, A., Mattern, B. C., Liebowitz, C., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyMorphological variations and asymmetry

Cited by 235

Insights into the genetic architecture of the human face

White, J. D., Indencleef, K., Naqvi, S., Eller, R. J., Hoskens, H., Roosenboom, J., Lee, M. K., Li, J., Mohammed, J., Richmond, S., et al. (2021) · Nature Genetics

Genetic Associations and EpidemiologyMorphological variations and asymmetry

Cited by 166

Precise modulation of transcription factor levels identifies features underlying dosage sensitivity

Naqvi, S., Kim, S., Hoskens, H., Matthews, H. S., Spritz, R. A., Klein, O. D., Hallgrímsson, B., Swigut, T., Claes, P., Pritchard, J. K., et al. (2023) · Nature Genetics

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 132

Temporal dissection of an enhancer cluster reveals distinct temporal and functional contributions of individual elements

Thomas, H. F., Kotova, E., Jayaram, S., Pilz, A., Romeike, M., Lackner, A., Penz, T., Bock, C., Leeb, M., Halbritter, F., et al. (2021) · Molecular Cell

Genomics and Chromatin DynamicsPluripotent Stem Cells Research

Cited by 98

Structural elements promote architectural stripe formation and facilitate ultra-long-range gene regulation at a human disease locus

Chen, L.-F., Long, H. K., Park, M., Swigut, T., Boettiger, A. N., & Wysocka, J. (2023) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 66

Long-range regulation of transcription scales with genomic distance in a gene-specific manner

Jensen, C. L., Chen, L.-F., Swigut, T., Crocker, O. J., Yao, D., Bassik, M. C., Ferrell, J. E., Boettiger, A. N., & Wysocka, J. (2025) · Molecular Cell

Genomics and Chromatin DynamicsCRISPR and Genetic Engineering

Cited by 39

Human genetic variation within neural crest enhancers: molecular and phenotypic implications

Rada-Iglesias, A., Prescott, S. L., & Wysocka, J. (2013) · Philosophical Transactions of the Royal Society B Biological Sciences

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 24

Transfer learning reveals sequence determinants of the quantitative response to transcription factor dosage

Naqvi, S., Kim, S., Tabatabaee, S., Pampari, A., Kundaje, A., Pritchard, J. K., & Wysocka, J. (2025) · Cell Genomics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 18