Wynn, Thomas A.

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids

Sampaziotis, F., Justin, A. W., Tysoe, O. C., Sawiak, S., Godfrey, E. M., Upponi, S. S., Gieseck, R. L., de Brito, M. C., Berntsen, N. L., Gómez-Vázquez, M. J., et al. (2017) · Nature Medicine

Tissue Engineering and Regenerative MedicinePediatric Hepatobiliary Diseases and Treatments

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Retnla (Relmα/Fizz1) Suppresses Helminth-Induced Th2-Type Immunity

Pesce, J. T., Ramalingam, T. R., Wilson, M. S., Mentink-Kane, M. M., Thompson, R. W., Cheever, A. W., Urban, J. F., & Wynn, T. A. (2009) · PLoS Pathogens

Parasites and Host InteractionsIL-33, ST2, and ILC Pathways

Cited by 213

Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis

Vannella, K. M., Ramalingam, T. R., Borthwick, L. A., Barron, L., Hart, K. M., Thompson, R. W., Kindrachuk, K. N., Cheever, A. W., White, S., Budelsky, A. L., et al. (2016) · Science Translational Medicine

IL-33, ST2, and ILC PathwaysAsthma and respiratory diseases

Cited by 188

Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β

Hart, K. M., Fabre, T., Sciurba, J. C., Gieseck, R. L., Borthwick, L. A., Vannella, K. M., Acciani, T. H., de Queiroz Prado, R., Thompson, R. W., White, S., et al. (2017) · Science Translational Medicine

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 143

Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis

Borthwick, L. A., Barron, L., Hart, K. M., Vannella, K. M., Thompson, R. W., Oland, S., Cheever, A., Sciurba, J., Ramalingam, T. R., Fisher, A. J., et al. (2016) · Mucosal Immunology

Asthma and respiratory diseasesImmune cells in cancer

Cited by 138

IL-13Rα2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice

Wilson, M. S., Elnekave, E., Mentink-Kane, M. M., Hodges, M. G., Pesce, J. T., Ramalingam, T. R., Thompson, R. W., Kamanaka, M., Flavell, R. A., Keane-Myers, A., et al. (2007) · Journal of Clinical Investigation

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 137

Interleukin-13 Activates Distinct Cellular Pathways Leading to Ductular Reaction, Steatosis, and Fibrosis

Gieseck, R. L., Ramalingam, T. R., Hart, K. M., Vannella, K. M., Cantu, D. A., Lu, W.-Y., Ferreira-González, S., Forbes, S. J., Vallier, L., & Wynn, T. A. (2016) · Immunity

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 132

Regional Differences in Human Biliary Tissues and Corresponding In Vitro–Derived Organoids

Rimland, C. A., Tilson, S. G., Morell, C. M., Tomaz, R. A., Lu, W., Adams, S. E., Georgakopoulos, N., Otaizo‐Carrasquero, F., Myers, T. G., Ferdinand, J. R., et al. (2021) · Hepatology

Liver physiology and pathologyCholangiocarcinoma and Gallbladder Cancer Studies

Cited by 110

T cells encountering myeloid cells programmed for amino acid-dependent immunosuppression use Rictor/mTORC2 protein for proliferative checkpoint decisions

Van de Velde, L.-A., Subramanian, C., Smith, A. M., Barron, L., Qualls, J. E., Neale, G., Alfonso-Pecchio, A., Jackowski, S., Rock, C. O., Wynn, T. A., et al. (2017) · Journal of Biological Chemistry

Immune cells in cancerT-cell and B-cell Immunology

Cited by 75

Repetitive intradermal bleomycin injections evoke T-helper cell 2 cytokine-driven pulmonary fibrosis

Singh, B., Kasam, R. K., Sontake, V., Wynn, T. A., & Madala, S. K. (2017) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisPulmonary Hypertension Research and Treatments

Cited by 48

Fibroblast‐specific integrin‐alpha V differentially regulates type 17 and type 2 driven inflammation and fibrosis

Sciurba, J. C., Gieseck, R. L., Jiwrajka, N., White, S. D., Karmele, E. P., Redes, J., Vannella, K. M., Henderson, N. C., Wynn, T. A., & Hart, K. M. (2019) · The Journal of Pathology

Cell Adhesion Molecules ResearchInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 22

Myeloid cells contribute to bystander CD8 T cell accumulation in metabolic-associated steatohepatitis and are sufficient for fibrosis

Lebeaupin, C., Donahue, K. L., Lal, S., Christensen, S. M., Asano, S., Wadsworth, M. H., Bound, K., De, S., McMahon, J., Schlerman, F., et al. (2025) · bioRxiv (preprint)

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

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