Fearon, Douglas T.

A framework for advancing our understanding of cancer-associated fibroblasts

Sahai, E., Astsaturov, I., Cukierman, E., DeNardo, D. G., Egeblad, M., Evans, R. M., Fearon, D., Greten, F. R., Hingorani, S. R., Hunter, T., et al. (2020) · Nature Reviews Cancer

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 3,863

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

Öhlund, D., Handly-Santana, A., Biffi, G., Elyada, E., Almeida, A. S., Ponz-Sarvise, M., Corbo, V., Oni, T. E., Hearn, S. A., Lee, E. J., et al. (2017) · Journal of Experimental Medicine

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 2,590

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

Feig, C., Jones, J. O., Kraman, M., Wells, R. J. B., Deonarine, A., Chan, D. S., Connell, C. M., Roberts, E. W., Zhao, Q., Caballero, O. L., et al. (2013) · Proceedings of the National Academy of Sciences

Cancer Immunotherapy and BiomarkersPancreatic and Hepatic Oncology Research

Cited by 2,100

Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice

Albrengues, J., Shields, M. A., Ng, D., Park, C. G., Ambrico, A., Poindexter, M. E., Upadhyay, P., Uyeminami, D. L., Pommier, A., Küttner, V., et al. (2018) · Science

Neutrophil, Myeloperoxidase and Oxidative MechanismsCancer, Stress, Anesthesia, and Immune Response

Cited by 1,476

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

Yamamoto, K., Venida, A., Yano, J., Biancur, D. E., Kakiuchi, M., Gupta, S., Sohn, A. S. W., Mukhopadhyay, S., Lin, E. Y., Parker, S. J., et al. (2020) · Nature

Autophagy in Disease and TherapyCancer Immunotherapy and Biomarkers

Cited by 1,240

C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity

Dempsey, P. W., Allison, M. E. D., Akkaraju, S., Goodnow, C. C., & Fearon, D. T. (1996) · Science

Complement system in diseasesImmunotherapy and Immune Responses

Cited by 1,197

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

Initiative, A. P. C. G., Balachandran, V. P., Łuksza, M., Zhao, J. N., Makarov, V., Moral, J. A., Remark, R., Herbst, B., Askan, G., Bhanot, U., et al. (2017) · Nature

Cancer Immunotherapy and BiomarkersPancreatic and Hepatic Oncology Research

Cited by 1,191

Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein–α

Kraman, M., Bambrough, P. J., Arnold, J. N., Roberts, E. W., Magiera, L., Jones, J. O., Gopinathan, A., Tuveson, D. A., & Fearon, D. T. (2010) · Science

Peptidase Inhibition and AnalysisImmune cells in cancer

Cited by 1,134

Distinct fibroblast subsets drive inflammation and damage in arthritis

Croft, A. P., Campos, J., Jansen, K., Turner, J. D., Marshall, J., Attar, M., Savary, L., Wehmeyer, C., Naylor, A. J., Kemble, S., et al. (2019) · Nature

Rheumatoid Arthritis Research and TherapiesOsteoarthritis Treatment and Mechanisms

Cited by 976

Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity

Flint, T. R., Janowitz, T., Connell, C. M., Roberts, E. W., Denton, A. E., Coll, A. P., Jodrell, D. I., & Fearon, D. T. (2016) · Cell Metabolism

Immune cells in cancerDietary Effects on Health

Cited by 367

The Carcinoma-Associated Fibroblast Expressing Fibroblast Activation Protein and Escape from Immune Surveillance

Fearon, D. T. (2014) · Cancer Immunology Research

Peptidase Inhibition and AnalysisCancer Immunotherapy and Biomarkers

Cited by 288

Arrested differentiation, the self-renewing memory lymphocyte, and vaccination

Fearon, D. T., Manders, P., & Wagner, S. D. (2001) · Science

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 265

Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology

Nayar, S., Campos, J., Smith, C. G., Iannizzotto, V., Gardner, D. H., Mourcin, F., Roulois, D., Turner, J., Sylvestre, M., Asam, S., et al. (2019) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyIL-33, ST2, and ILC Pathways

Cited by 203

Loss of T cell receptor-induced Bmi-1 in the KLRG1 + senescent CD8 + T lymphocyte

Heffner, M., & Fearon, D. T. (2007) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyTelomeres, Telomerase, and Senescence

Cited by 92