Wilen, Craig B.

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

Doench, J. G., Fusi, N., Sullender, M., Hegde, M., Vaimberg, E. W., Donovan, K. F., Smith, I., Tothova, Z., Wilen, C., Orchard, R., et al. (2016) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 4,637

Neuroinvasion of SARS-CoV-2 in human and mouse brain

Song, E., Zhang, C., Israelow, B., Lu-Culligan, A., Prado, A. V., Skriabine, S., Lu, P., Weizman, O.-E., Liu, F., Dai, Y., et al. (2020) · The Journal of Experimental Medicine

Long-Term Effects of COVID-19SARS-CoV-2 and COVID-19 Research

Cited by 1,064

HIV: Cell Binding and Entry

Wilen, C. B., Tilton, J. C., & Doms, R. W. (2012) · Cold Spring Harbor Perspectives in Medicine

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 654

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

Israelow, B., Song, E., Mao, T., Lu, P., Meir, A., Liu, F., Alfajaro, M. M., Wei, J., Dong, H., Homer, R. J., et al. (2020) · Journal of Experimental Medicine

SARS-CoV-2 and COVID-19 Researchinterferon and immune responses

Cited by 415

Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes

Ravindra, N. G., Alfajaro, M. M., Gasque, V., Huston, N. C., Wan, H., Szigeti-Buck, K., Yasumoto, Y., Greaney, A. M., Habet, V., Chow, R. D., et al. (2021) · PLOS Biology

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 258

Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases

Wilen, C. B., Wang, J., Tilton, J. C., Miller, J. C., Kim, K. A., Rebar, E. J., Sherrill-Mix, S. A., Patro, S. C., Secreto, A. J., Jordan, A. P. O., et al. (2011) · PLoS Pathogens

HIV Research and TreatmentCRISPR and Genetic Engineering

Cited by 142

A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5

Tilton, J. C., Wilen, C. B., Didigu, C. A., Sinha, R., Harrison, J. E., Agrawal-Gamse, C., Henning, E. A., Bushman, F. D., Martin, J. N., Deeks, S. G., et al. (2010) · Journal of Virology

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 110

Criteria for reducing unnecessary testing for herpes simplex virus, varicella-zoster virus, cytomegalovirus, and enterovirus in cerebrospinal fluid samples from adults

Wilen, C. B., Monaco, C. L., Hoppe-Bauer, J., Jackups, R., Bucelli, R. C., & Burnham, C.-A. D. (2015) · Journal of Clinical Microbiology

Healthcare cost, quality, practicesHerpesvirus Infections and Treatments

Cited by 27

Variant-specific vaccination induces systems immune responses and potent in vivo protection against SARS-CoV-2

Peng, L., Renauer, P. A., Ökten, A., Fang, Z., Park, J. J., Zhou, X., Lin, Q., Dong, M. B., Filler, R., Xiong, Q., et al. (2022) · Cell Reports Medicine

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

Cited by 21