Wollert, Kai C.

The Transforming Growth Factor-β Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury

Kempf, T., Eden, M., Strelau, J., Naguib, M., Willenbockel, C., Tongers, J., Heineke, J., Kotlarz, D., Xu, J., Molkentin, J. D., et al. (2006) · Circulation Research

GDF15 and Related BiomarkersCardiac Ischemia and Reperfusion

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GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice

Kempf, T., Zarbock, A., Widera, C., Butz, S., Stadtmann, A., Rossaint, J., Bolomini-Vittori, M., Korf-Klingebiel, M., Napp, L. C., Hansen, B., et al. (2011) · Nature Medicine

GDF15 and Related BiomarkersCardiac Fibrosis and Remodeling

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Prognostic Utility of Novel Biomarkers of Cardiovascular Stress: The Framingham Heart Study

Wang, T. J., Wollert, K. C., Larson, M. G., Coglianese, E., McCabe, E. L., Cheng, S., Ho, J. E., Fradley, M. G., Ghorbani, A., Xanthakis, V., et al. (2012) · Circulation

GDF15 and Related BiomarkersHeart Failure Treatment and Management

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Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury

Hilfiker-Kleiner, D., Hilfiker, A., Fuchs, M., Kaminski, K., Schaefer, A., Schieffer, B., Hillmer, A., Schmiedl, A., Ding, Z., Podewski, E., et al. (2004) · Circulation Research

Cardiac Fibrosis and RemodelingCytokine Signaling Pathways and Interactions

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Ideal Cardiovascular Health: Associations With Biomarkers and Subclinical Disease and Impact on Incidence of Cardiovascular Disease in the Framingham Offspring Study

Xanthakis, V., Enserro, D. M., Murabito, J. M., Polak, J. F., Wollert, K. C., Januzzi, J. L., Wang, T. J., Tofler, G., & Vasan, R. S. (2014) · Circulation

Cardiovascular Health and Risk FactorsCardiovascular Health and Disease Prevention

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Molecular Imaging of the Chemokine Receptor CXCR4 After Acute Myocardial Infarction

Thackeray, J. T., Derlin, T., Haghikia, A., Napp, L. C., Wang, Y., Ross, T. L., Schäfer, A., Tillmanns, J., Wester, H. J., Wollert, K. C., et al. (2015) · JACC: Cardiovascular Imaging

Cardiac Imaging and DiagnosticsChemokine receptors and signaling

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Growth differentiation factor 15 predicts future insulin resistance and impaired glucose control in obese nondiabetic individuals: results from the XENDOS trial

Kempf, T., Guba-Quint, A., Torgerson, J., Magnone, M. C., Haefliger, C., Bobadilla, M., & Wollert, K. C. (2012) · European Journal of Endocrinology

GDF15 and Related BiomarkersAdipokines, Inflammation, and Metabolic Diseases

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Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction

Bär, C., de Jesus, B. B., Serrano, R., Tejera, A., Ayuso, E., Jimenez, V., Formentini, I., Bobadilla, M., Mizrahi, J., de Martino, A., et al. (2014) · Nature Communications

Congenital heart defects researchTelomeres, Telomerase, and Senescence

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Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors

Schledzewski, K., Géraud, C., Arnold, B., Wang, S., Gröne, H.-J., Kempf, T., Wollert, K. C., Straub, B. K., Schirmacher, P., Demory, A., et al. (2011) · Journal of Clinical Investigation

Chronic Kidney Disease and DiabetesRenal Diseases and Glomerulopathies

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Regulation of Proangiogenic Factor CCN1 in Cardiac Muscle: Impact of Ischemia, Pressure Overload, and Neurohumoral Activation

Hilfiker-Kleiner, D., Kaminski, K., Kaminska, A., Fuchs, M., Klein, G., Podewski, E., Grote, K., Kiian, I., Wollert, K. C., Hilfiker, A., et al. (2004) · Circulation

Connective Tissue Growth Factor ResearchCardiac Fibrosis and Remodeling

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Myeloid-Derived Growth Factor Protects Against Pressure Overload–Induced Heart Failure by Preserving Sarco/Endoplasmic Reticulum Ca 2+ -ATPase Expression in Cardiomyocytes

Korf-Klingebiel, M., Reboll, M. R., Polten, F., Weber, N., Jäckle, F., Wu, X., Kallikourdis, M., Kunderfranco, P., Condorelli, G., Giannitsis, E., et al. (2021) · Circulation

Cardiac Fibrosis and RemodelingCardiovascular Function and Risk Factors

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EMC10 (Endoplasmic Reticulum Membrane Protein Complex Subunit 10) Is a Bone Marrow–Derived Angiogenic Growth Factor Promoting Tissue Repair After Myocardial Infarction

Reboll, M. R., Korf-Klingebiel, M., Klede, S., Polten, F., Brinkmann, E., Reimann, I., Schönfeld, H.-J., Bobadilla, M., Faix, J., Kensah, G., et al. (2017) · Circulation

Mesenchymal stem cell researchCardiac Fibrosis and Remodeling

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Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans

Lemmelä, S., Wigmore, E. M., Benner, C., Havulinna, A. S., Ong, R. M., Kempf, T., Wollert, K. C., Blankenberg, S., Zeller, T., Peters, J. E., et al. (2022) · eLife

GDF15 and Related BiomarkersGenetic Associations and Epidemiology

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