Melander, Olle

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

Vujkovic, M., Keaton, J. M., Lynch, J. A., Miller, D. R., Zhou, J., Tcheandjieu, C., Huffman, J. E., Assimes, T. L., Lorenz, K., Zhu, X., et al. (2020) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 741

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, Å. K., Schork, A., Page, K., Zhernakova, D. V., Wu, Y., Peters, J., et al. (2020) · Nature Metabolism

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 705

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials

Mega, J. L., Stitziel, N. O., Smith, J. G., Chasman, D. I., Caulfield, M. J., Devlin, J. J., Nordio, F., Hyde, C. L., Cannon, C. P., Sacks, F. M., et al. (2015) · The Lancet

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 704

Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events

Kathiresan, S., Melander, O., Anevski, D., Guiducci, C., Burtt, N. P., Roos, C., Hirschhorn, J. N., Berglund, G., Hedblad, B., Groop, L., et al. (2008) · New England Journal of Medicine

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 696

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Holmes, M. V., Dale, C. E., Zuccolo, L., Silverwood, R. J., Guo, Y., Ye, Z., Prieto-Merino, D., Dehghan, A., Trompet, S., Wong, A., et al. (2014) · BMJ

Alcohol Consumption and Health EffectsGenetic Associations and Epidemiology

Cited by 669

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., et al. (2024) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 606

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

Ellinor, P. T., Lunetta, K. L., Albert, C. M., Glazer, N. L., Ritchie, M. D., Smith, A. V., Arking, D. E., Müller-Nurasyid, M., Krijthe, B. P., Lubitz, S. A., et al. (2012) · Nature Genetics

Atrial Fibrillation Management and OutcomesGenetic Associations and Epidemiology

Cited by 601

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

Ripatti, S., Tikkanen, E., Orho-Melander, M., Havulinna, A. S., Silander, K., Sharma, A., Guiducci, C., Perola, M., Jula, A., Sinisalo, J., et al. (2010) · The Lancet

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

Cited by 562

New susceptibility locus for coronary artery disease on chromosome 3q22.3

Italian Atherosclerosis, T., Erdmann, J., Myocardial Infarction Genetics Consortium, Wellcome Trust Case Control Consortium, Cardiogenics Consortium, Großhennig, A., Braund, P. S., König, I. R., Hengstenberg, C., Hall, A. S., et al. (2009) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 484

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 442

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

CHARGE-Heart Failure Consortium, Surendran, P., EchoGen Consortium, METASTROKE Consortium, GIANT Consortium, EPIC-InterAct Consortium, Study, L. C., Wellcome Trust Case Control Consortium, Understanding Society Scientific Group, EPIC-CVD Consortium, et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 312

Plasma Copeptin and the Risk of Diabetes Mellitus

Enhörning, S., Wang, T. J., Nilsson, P. M., Almgren, P., Hedblad, B., Berglund, G., Struck, J., Morgenthaler, N. G., Bergmann, A., Lindholm, E., et al. (2010) · Circulation

Electrolyte and hormonal disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 299

Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history

Tada, H., Melander, O., Louie, J. Z., Catanese, J. J., Rowland, C. M., Devlin, J. J., Kathiresan, S., & Shiffman, D. (2016) · European Heart Journal

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

Cited by 285

Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity

Akbari, P., Gilani, A., Sosina, O., Kosmicki, J. A., Khrimian, L., Fang, Y.-Y., Persaud, T., Garcia, V., Sun, D., Li, A., et al. (2021) · Science

Genetic Associations and EpidemiologyRegulation of Appetite and Obesity

Cited by 276

Atrial fibrillation in the Malmö diet and cancer study: a study of occurrence, risk factors and diagnostic validity

Smith, J. G., Platonov, P. G., Hedblad, B., Engström, G., & Melander, O. (2010) · European Journal of Epidemiology

Atrial Fibrillation Management and OutcomesCardiovascular Health and Risk Factors

Cited by 275

Fruit and vegetable intake and mortality from ischaemic heart disease: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart study

Crowe, F. L., Roddam, A. W., Key, T. J., Appleby, P. N., Overvad, K., Jakobsen, M. U., Tjonneland, A., Hansen, L., Boeing, H., Weikert, C., et al. (2011) · European Heart Journal

Nutritional Studies and DietCardiovascular Health and Risk Factors

Cited by 263

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

Sinner, M. F., Tucker, N. R., Lunetta, K. L., Ozaki, K., Smith, J. G., Trompet, S., Bis, J. C., Lin, H., Chung, M. K., Nielsen, J. B., et al. (2014) · Circulation

Cardiac electrophysiology and arrhythmiasAtrial Fibrillation Management and Outcomes

Cited by 205

Plasma Copeptin, A Unifying Factor behind the Metabolic Syndrome

Enhörning, S., Struck, J., Wirfält, E., Hedblad, B., Morgenthaler, N. G., & Melander, O. (2011) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 177

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes

Mansour Aly, D., Dwivedi, O. P., Prasad, R. B., Käräjämäki, A., Hjort, R., Thangam, M., Åkerlund, M., Mahajan, A., Udler, M. S., Florez, J. C., et al. (2021) · Nature Genetics

Genetic Associations and EpidemiologyDiabetes and associated disorders

Cited by 172

Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization

Zhou, W., Liu, G., Hung, R. J., Haycock, P. C., Aldrich, M. C., Andrew, A. S., Arnold, S. M., Bickeböller, H., Bojesen, S. E., Brennan, P., et al. (2021) · International Journal of Cancer

Genetic Associations and EpidemiologyCancer Risks and Factors

Cited by 172

Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk.

Musunuru, K., Orho-Melander, M., Caulfield, M. P., Li, S., Salameh, W. A., Reitz, R. E., Berglund, G., Hedblad, B., Engström, G., Williams, P. T., et al. (2009) · Arteriosclerosis, Thrombosis, and Vascular Biology

Lipoproteins and Cardiovascular HealthDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 168

Syndromes of orthostatic intolerance: a hidden danger

Fedorowski, A., & Melander, O. (2013) · Journal of Internal Medicine

Cardiovascular Syncope and Autonomic DisordersHeart Rate Variability and Autonomic Control

Cited by 151

Antiadrenergic autoimmunity in postural tachycardia syndrome

Fedorowski, A., Li, H., Yu, X., Koelsch, K. A., Harris, V. M., Liles, C., Murphy, T. A., Quadri, S. M. S., Scofield, R. H., Sutton, R., et al. (2017) · EP Europace

Cardiovascular Syncope and Autonomic DisordersHeart Rate Variability and Autonomic Control

Cited by 151

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Voight, B. F., Peloso, G. M., Orho-Melander, M., Frikke-Schmidt, R., Barbalic, M., Jensen, M. K., Hindy, G., Hólm, H., Ding, E. L., Johnson, T., et al. (2012) · The Lancet

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 148