Goebbels, Sandra

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

Fünfschilling, U., Supplie, L. M., Mahad, D., Boretius, S., Saab, A. S., Edgar, J., Brinkmann, B. G., Kassmann, C. M., Tzvetanova, I. D., Möbius, W., et al. (2012) · Nature

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Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination

Lappe-Siefke, C., Goebbels, S., Gravel, M., Nicksch, E., Lee, J., Braun, P. E., Griffiths, I. R., & Nave, K.-A. (2003) · Nature Genetics

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

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Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

Frühbeis, C., Fröhlich, D., Kuo, W. P., Amphornrat, J., Thilemann, S., Saab, A. S., Kirchhoff, F., Möbius, W., Goebbels, S., Nave, K.-A., et al. (2013) · PLoS Biology

Extracellular vesicles in diseaseCellular transport and secretion

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The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus

Monory, K., Massa, F., Egertová, M., Eder, M., Blaudzun, H., Westenbroek, R., Kelsch, W., Jacob, W., Marsch, R., Ekker, M., et al. (2006) · Neuron

Cannabis and Cannabinoid ResearchEpilepsy research and treatment

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Neurod1 is essential for the survival and maturation of adult-born neurons

Gao, Z., Ure, K., Ables, J. L., Lagace, D. C., Nave, K.-A., Goebbels, S., Eisch, A. J., & Hsieh, J. (2009) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

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Notch1 control of oligodendrocyte differentiation in the spinal cord

Genoud, S., Lappe-Siefke, C., Goebbels, S., Radtke, F., Aguet, M., Scherer, S. S., Suter, U., Nave, K.-A., & Mantei, N. (2002) · The Journal of Cell Biology

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Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone

Wu, S.-X., Goebbels, S., Nakamura, K., Nakamura, K., Kometani, K., Minato, N., Kaneko, T., Nave, K.-A., & Tamamaki, N. (2005) · Proceedings of the National Academy of Sciences

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Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice

Sasmita, A. O., Depp, C., Nazarenko, T., Sun, T., Siems, S. B., Ong, E. C., Nkeh, Y. B., Böhler, C., Yu, X., Bues, B., et al. (2024) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

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Microglia ablation alleviates myelin-associated catatonic signs in mice

Janova, H., Arinrad, S., Balmuth, E., Mitjans, M., Hertel, J., Habes, M., Bittner, R. A., Pan, H., Goebbels, S., Begemann, M., et al. (2017) · Journal of Clinical Investigation

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

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Oligodendrocyte gene expression is reduced by and influences effects of chronic social stress in mice

Cathomas, F., Azzinnari, D., Bergamini, G., Sigrist, H., Buerge, M., Hoop, V., Wicki, B., Goetze, L., Soares, S., Kukelova, D., et al. (2019) · Genes, Brain and Behavior

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Axonal integrity in the absence of functional peroxisomes from projection neurons and astrocytes

Bottelbergs, A., Verheijden, S., Hulshagen, L., Gutmann, D. H., Goebbels, S., Nave, K., Kassmann, C., & Baes, M. (2010) · Glia

Metabolism and Genetic DisordersHereditary Neurological Disorders

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Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons

Späte, E., Zhou, B., Sun, T., Kusch, K., Asadollahi, E., Siems, S. B., Depp, C., Werner, H. B., Saher, G., Hirrlinger, J., et al. (2024) · Glia

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The polarity protein Scribble regulates myelination and remyelination in the central nervous system

Jarjour, A. A., Boyd, A., Dow, L. E., Holloway, R. K., Goebbels, S., Humbert, P. O., Williams, A., & ffrench-Constant, C. (2015) · PLOS Biology

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