Germain, Pierre-Luc

Doublet identification in single-cell sequencing data using scDblFinder

Germain, P.-L., Lun, A., Garcia Meixide, C., Macnair, W., & Robinson, M. D. (2022) · F1000Research

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 684

muscat detects subpopulation-specific state transitions from multi-sample multi-condition single-cell transcriptomics data

Crowell, H. L., Soneson, C., Germain, P.-L., Calini, D., Collin, L., Raposo, C., Malhotra, D., & Robinson, M. D. (2020) · Nature Communications

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 515

From cohorts to molecules: adverse impacts of endocrine disrupting mixtures

Caporale, N., Leemans, M., Birgersson, L., Germain, P.-L., Cheroni, C., Borbély, G., Engdahl, E., Lindh, C., Bressan, R. B., Cavallo, F., et al. (2022) · Science

Effects and risks of endocrine disrupting chemicalsToxic Organic Pollutants Impact

Cited by 368

Multi-omic measurements of heterogeneity in HeLa cells across laboratories

Liu, Y., Mi, Y., Mueller, T., Kreibich, S., Williams, E. G., Van Drogen, A., Borel, C., Frank, M., Germain, P.-L., Bludau, I., et al. (2019) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsViral Infectious Diseases and Gene Expression in Insects

Cited by 338

Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma

Gapp, K., van Steenwyk, G., Germain, P. L., Matsushima, W., Rudolph, K. L. M., Manuella, F., Roszkowski, M., Vernaz, G., Ghosh, T., Pelczar, P., et al. (2020) · Molecular Psychiatry

Epigenetics and DNA MethylationSperm and Testicular Function

Cited by 195

YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction

Gabriele, M., Vulto-van Silfhout, A. T., Germain, P.-L., Vitriolo, A., Kumar, R., Douglas, E., Haan, E., Kosaki, K., Takenouchi, T., Rauch, A., et al. (2017) · The American Journal of Human Genetics

Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases

Cited by 163

Systematic proteome and proteostasis profiling in human trisomy 21 fibroblast cells

Liu, Y., Borel, C., Li, L., Müller, T., Williams, E. G., Germain, P.-L., Buljan, M., Sajic, T., Boersema, P. J., Shao, W., et al. (2017) · Nature Communications

Down syndrome and intellectual disability researchAdvanced Proteomics Techniques and Applications

Cited by 141

7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages

Adamo, A., Atashpaz, S., Germain, P.-L., Zanella, M., D'Agostino, G., Albertin, V., Chenoweth, J., Micale, L., Fusco, C., Unger, C., et al. (2015) · Nature Genetics

Williams Syndrome ResearchPluripotent Stem Cells Research

Cited by 129

Dosage analysis of the 7q11.23 Williams region identifies BAZ1B as a major human gene patterning the modern human face and underlying self-domestication

Zanella, M., Vitriolo, A., Andirko, A., Martins, P. T., Sturm, S., O’Rourke, T., Laugsch, M., Malerba, N., Skaros, A., Trattaro, S., et al. (2019) · Science Advances

Williams Syndrome ResearchCraniofacial Disorders and Treatments

Cited by 101

Taming Human Genetic Variability: Transcriptomic Meta-Analysis Guides the Experimental Design and Interpretation of iPSC-Based Disease Modeling

Germain, P.-L., & Testa, G. (2017) · Stem Cell Reports

Pluripotent Stem Cells ResearchSingle-cell and spatial transcriptomics

Cited by 94

The Acute Stress Response in the Multiomic Era

Floriou-Servou, A., von Ziegler, L., Waag, R., Schläppi, C., Germain, P.-L., & Bohacek, J. (2021) · Biological Psychiatry

Stress Responses and CortisolMemory and Neural Mechanisms

Cited by 51

MicroRNA‐138‐5p suppresses excitatory synaptic strength at the cerebellar input layer

Delvendahl, I., Daswani, R., Winterer, J., Germain, P., Uhr, N. M., Schratt, G., & Müller, M. (2025) · The Journal of Physiology

Neuroscience and Neuropharmacology ResearchMicroRNA in disease regulation

Cited by 3