Evans, Ronald M.

A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response

Ding, N., Yu, R. T., Subramaniam, N., Sherman, M. H., Wilson, C., Rao, R., Leblanc, M., Coulter, S., He, M., Scott, C., et al. (2013) · Cell

Liver physiology and pathologyTGF-β signaling in diseases

Cited by 622

Expression in Brain of a Messenger RNA Encoding a Novel Neuropeptide Homologous to Calcitonin Gene-Related Peptide

Amara, S. G., Arriza, J. L., Leff, S. E., Swanson, L. W., Evans, R. M., & Rosenfeld, M. G. (1985) · Science

Neuropeptides and Animal PhysiologyMigraine and Headache Studies

Cited by 610

The neuronal mineralocorticoid eeceptor as a mediator of glucocorticoid response

Arriza, J. L., Simerly, R. B., Swanson, L. W., & Evans, R. M. (1988) · Neuron

Estrogen and related hormone effectsStress Responses and Cortisol

Cited by 591

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

Lamia, K. A., Papp, S. J., Yu, R. T., Barish, G. D., Uhlenhaut, N. H., Jonker, J. W., Downes, M., & Evans, R. M. (2011) · Nature

Circadian rhythm and melatoninEstrogen and related hormone effects

Cited by 590

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

Shalapour, S., Lin, X.-J., Bastian, I. N., Brain, J., Burt, A. D., Aksenov, A. A., Vrbanac, A. F., Li, W., Perkins, A., Matsutani, T., et al. (2017) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 589

Effects of peroxisome proliferator-activated receptor δ on placentation, adiposity, and colorectal cancer

Barak, Y., Liao, D., He, W., Ong, E. S., Nelson, M. C., Olefsky, J. M., Boland, R., & Evans, R. M. (2002) · Proceedings of the National Academy of Sciences

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 586

Global chemical effects of the microbiome include new bile-acid conjugations

Quinn, R. A., Melnik, A. V., Vrbanac, A., Fu, T., Patras, K. A., Christy, M. P., Bodai, Z., Belda-Ferre, P., Tripathi, A., Chung, L. K., et al. (2020) · Nature

Gut microbiota and healthMetabolomics and Mass Spectrometry Studies

Cited by 579

PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3

Koo, S.-H., Satoh, H., Herzig, S., Lee, C.-H., Hedrick, S., Kulkarni, R., Evans, R. M., Olefsky, J., & Montminy, M. (2004) · Nature Medicine

Peroxisome Proliferator-Activated ReceptorsMetabolism, Diabetes, and Cancer

Cited by 550

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

Lam, M. T. Y., Cho, H., Lesch, H. P., Gosselin, D., Heinz, S., Tanaka-Oishi, Y., Benner, C., Kaikkonen, M. U., Kim, A. S., Kosaka, M., et al. (2013) · Nature

Genomics and Chromatin DynamicsCancer-related molecular mechanisms research

Cited by 548

International Union of Pharmacology. LXIII. Retinoid X receptors

Germain, P., Chambon, P., Eichele, G., Evans, R. M., Lazar, M. A., Leid, M., De Lera, A. R., Lotan, R., Mangelsdorf, D. J., & Gronemeyer, H. (2006) · Pharmacological Reviews

Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors

Cited by 496

Cardiomyocyte-restricted peroxisome proliferator-activated receptor-δ deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy

Cheng, L., Ding, G., Qin, Q., Huang, Y., Lewis, W., He, N., Evans, R. M., Schneider, M. D., Brako, F. A., Xiao, Y., et al. (2004) · Nature Medicine

Peroxisome Proliferator-Activated ReceptorsCardiovascular Function and Risk Factors

Cited by 453

Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis

Seidman, J. S., Troutman, T. D., Sakai, M., Gola, A., Spann, N. J., Bennett, H., Bruni, C. M., Ouyang, Z., Li, R. Z., Sun, X., et al. (2020) · Immunity

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 443

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Shi, Y., Gao, W., Lytle, N. K., Huang, P., Yuan, X., Dann, A. M., Ridinger-Saison, M., DelGiorno, K. E., Antal, C. E., Liang, G., et al. (2019) · Nature

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 431

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

Zhang, Y., Xie, Y., Berglund, E. D., Coate, K. C., He, T. T., Katafuchi, T., Xiao, G., Potthoff, M. J., Wei, W., Wan, Y., et al. (2012) · eLife

Fibroblast Growth Factor ResearchGenetics, Aging, and Longevity in Model Organisms

Cited by 420

Phosphorylation of CREB at Ser-133 Induces Complex Formation with CREB-Binding Protein via a Direct Mechanism

Parker, D., Ferreri, K., Nakajima, T., Lamorte, V. J., Evans, R., Koerber, S. C., Hoeger, C., & Montminy, M. R. (1996) · Molecular and Cellular Biology

Protein Kinase Regulation and GTPase SignalingGenomics and Chromatin Dynamics

Cited by 408

Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor

Oro, A. E., McKeown, M., & Evans, R. M. (1990) · Nature

Retinoids in leukemia and cellular processesDevelopmental Biology and Gene Regulation

Cited by 406

Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis

Chung, H. K., Ryu, D., Kim, K. S., Chang, J. Y., Kim, Y. K., Yi, H.-S., Kang, S. G., Choi, M. J., Lee, S. E., Jung, S.-B., et al. (2017) · Journal of Cell Biology

GDF15 and Related BiomarkersAdipose Tissue and Metabolism

Cited by 357

A Viral Mechanism for Inhibition of p300 and PCAF Acetyltransferase Activity

Chakravarti, D., Ogryzko, V., Kao, H.-Y., Nash, A., Chen, H., Nakatani, Y., & Evans, R. M. (1999) · Cell

Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research

Cited by 339

A Gut Microbiome Signature for Cirrhosis Due to Nonalcoholic Fatty Liver Disease

Caussy, C., Tripathi, A., Humphrey, G., Bassirian, S., Singh, S., Faulkner, C., Bettencourt, R., Rizo, E., Richards, L., Xu, Z. Z., et al. (2019) · Nature Communications

Gut microbiota and healthLiver Disease Diagnosis and Treatment

Cited by 338

Immune-evasive human islet-like organoids ameliorate diabetes

Yoshihara, E., O’Connor, C., Gasser, E., Wei, Z., Oh, T. G., Tseng, T. W., Wang, D., Cayabyab, F., Dai, Y., Yu, R. T., et al. (2020) · Nature

Pancreatic function and diabetesPluripotent Stem Cells Research

Cited by 333

A Stromal Lysolipid–Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression

Auciello, F. R., Bulusu, V., Oon, C., Tait-Mulder, J., Berry, M., Bhattacharyya, S., Tumanov, S., Allen-Petersen, B. L., Link, J., Kendsersky, N. D., et al. (2019) · Cancer Discovery

Sphingolipid Metabolism and SignalingPancreatic and Hepatic Oncology Research

Cited by 332

PPARδ is a very low-density lipoprotein sensor in macrophages

Chawla, A., Lee, C.-H., Barak, Y., He, W., Rosenfeld, J., Liao, D., Han, J., Kang, H., & Evans, R. M. (2003) · Proceedings of the National Academy of Sciences

Peroxisome Proliferator-Activated ReceptorsCholesterol and Lipid Metabolism

Cited by 305

Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice

Hartmann, P., Hochrath, K., Horvath, A., Chen, P., Seebauer, C. T., Llorente, C., Wang, L., Alnouti, Y., Fouts, D. E., Stärkel, P., et al. (2018) · Hepatology

Gut microbiota and healthAlcohol Consumption and Health Effects

Cited by 290

PGC-1β controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis

Sonoda, J., Mehl, I. R., Chong, L.-W., Nofsinger, R. R., & Evans, R. M. (2007) · Proceedings of the National Academy of Sciences

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 266