Phosphorylation of CREB at Ser-133 Induces Complex Formation with CREB-Binding Protein via a Direct Mechanism

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

Gonzalez, G. A., & Montminy, M. (1989) · Cell · doi:10.1016/0092-8674(89)90013-5 · Cited by 2,464 · see citing works

Phosphorylated CREB binds specifically to the nuclear protein CBP

Chrivia, J. C., Kwok, R. P. S., Lamb, N., Hagiwara, M., Montminy, M. R., & Goodman, R. H. (1993) · Nature · doi:10.1038/365855a0 · Cited by 2,052 · see citing works

Nuclear protein CBP is a coactivator for the transcription factor CREB

Kwok, R. P. S., Lundblad, J. R., Chrivia, J. C., Richards, J. P., Bächinger, H. P., Brennan, R. G., Roberts, S. G. E., Green, M. R., & Goodman, R. H. (1994) · Nature · doi:10.1038/370223a0 · Cited by 1,443 · see citing works

The regulation of transcription by phosphorylation

Hunter, T. R., & Karin, M. (1992) · Cell · doi:10.1016/0092-8674(92)90162-6 · Cited by 1,273 · see citing works

Circular dichroic analysis of protein conformation: Inclusion of the β-turns

Chang, C. T., Wu, C. C., & Yang, J. T. (1978) · Analytical Biochemistry · doi:10.1016/0003-2697(78)90812-6 · Cited by 1,090 · see citing works

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.Preprint

Eckner, R., Ewen, M. E., Newsome, D., Gerdes, M., DeCaprio, J. A., Lawrence, J. B., & Livingston, D. M. (1994) · Genes & Development · doi:10.1101/gad.8.8.869 · Cited by 1,045 · see citing works

SH2 and SH3 domains: From structure to function

Pawson, T. J., & Gish, G. D. (1992) · Cell · doi:10.1016/0092-8674(92)90504-6 · Cited by 949 · see citing works

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

Mathews, L. S., & Vale, W. (1991) · Cell · doi:10.1016/0092-8674(91)90549-e · Cited by 753 · see citing works

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

Arias, J., Alberts, A. S., Brindle, P. K., Claret, F. X., Smeal, T., Karin, M., Feramisco, J. R., & Montminy, M. (1994) · Nature · doi:10.1038/370226a0 · Cited by 726 · see citing works

A method for random mutagenesis of a defined DNA segment using a modified polymerase chain reaction

Leung, D., Chen, E., & Dv, G. (1989) · Medical Entomology and Zoology · Cited by 610 · see citing works

Coupling of Hormonal Stimulation and Transcription via the Cyclic AMP-Responsive Factor CREB Is Rate Limited by Nuclear Entry of Protein Kinase A

Hagiwara, M., Brindle, P. K., Harootunian, A. T., Armstrong, R., Rivier, J., Vale, W., Tsien, R. Y., & Montminy, M. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.8.4852-4859.1993 · Cited by 452 · see citing works

Structural changes in glycogen phosphorylase induced by phosphorylation

Sprang, S. R., Acharya, K. R., Goldsmith, E. J., Stuart, D. I., Varvill, K. M., Fletterick, R. J., Madsen, N. B., & Johnson, L. N. (1988) · Nature · doi:10.1038/336215a0 · Cited by 299 · see citing works

Regulation of an Enzyme by Phosphorylation at the Active Site

Hurley, J. H., Dean, A. M., Sohl, J. L., Koshland, D. E., & Stroud, R. M. (1990) · Science · doi:10.1126/science.2204109 · Cited by 249 · see citing works

Protein-kinase-A-dependent activator in transcription factor CREB reveals new role for CREM repressers

Brindle, P. K., Linke, S., & Montminy, M. (1993) · Nature · doi:10.1038/364821a0 · Cited by 173 · see citing works

Construction of Mammalian Cell Lines with Indicator Genes Driven by Regulated Promoters

Meinkoth, J. L., Alberts, A. S., & Feramisco, J. R. (2007) · Novartis Foundation symposium · doi:10.1002/9780470513927.ch4 · Cited by 22 · see citing works

Crosslinking transcription factors to their recognition sequences with PtIIcomplexes

Chu, B. C. F., & Orgel, L. E. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.10.2497 · Cited by 14 · see citing works

Transcriptional regulation by the phosphorylation-dependent factor CREB

Mayr, B., & Montminy, M. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35085068 · Cited by 2,587 · see citing works

CREB: A Stimulus-Induced Transcription Factor Activated by A Diverse Array of Extracellular Signals

Shaywitz, A. J., & Greenberg, M. E. (1999) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.68.1.821 · Cited by 2,135 · see citing works

Function and regulation of CREB family transcription factors in the nervous system

Lonze, B. E., & Ginty, D. D. (2002) · Neuron · doi:10.1016/s0896-6273(02)00828-0 · Cited by 2,127 · see citing works

The multifaceted roles of glycogen synthase kinase 3β in cellular signaling

Grimes, C. A., & Jope, R. S. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(01)00011-9 · Cited by 1,429 · see citing works

Shaping the nuclear action of NF-κB

Chen, L., & Greene, W. C. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1368 · Cited by 1,219 · see citing works

Toll-like receptor–mediated cytokine production is differentially regulated by glycogen synthase kinase 3

Martin, M., Rehani, K., Jope, R. S., & Michalek, S. M. (2005) · Nature Immunology · doi:10.1038/ni1221 · Cited by 1,080 · see citing works

Mechanism of coupled folding and binding of an intrinsically disordered protein

Sugase, K., Dyson, H. J., & Wright, P. E. (2007) · Nature · doi:10.1038/nature05858 · Cited by 1,040 · see citing works

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

Altarejos, J. Y., & Montminy, M. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3072 · Cited by 1,035 · see citing works

Phosphorylation of NF-κB p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300

Zhong, H., Voll, R. E., & Ghosh, S. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80066-0 · Cited by 1,210 · see citing works

Gene Dosage–Dependent Embryonic Development and Proliferation Defects in Mice Lacking the Transcriptional Integrator p300

Yao, T., Oh, S. P., Fuchs, M., Zhou, N.-D., Ch'ng, L.-E., Newsome, D., Bronson, R. T., Li, E., Livingston, D. M., & Eckner, R. (1998) · Cell · doi:10.1016/s0092-8674(00)81165-4 · Cited by 1,015 · see citing works

TRANSCRIPTIONAL REGULATION BY CYCLIC AMP

Montminy, M. (1997) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.66.1.807 · Cited by 961 · see citing works

Role of CBP/P300 in nuclear receptor signalling

Chakravarti, D., LaMorte, V. J., Nelson, M. C., Nakajima, T., Schulman, I. G., Juguilon, H., Montminy, M., & Evans, R. M. (1996) · Nature · doi:10.1038/383099a0 · Cited by 930 · see citing works

Chromatin Acetylation, Memory, and LTP Are Impaired in CBP+/− Mice

Alarcón, J. M., Malleret, G., Touzani, K., Vronskaya, S., Ishii, S., Kandel, E. R., & Barco, A. (2004) · Neuron · doi:10.1016/j.neuron.2004.05.021 · Cited by 892 · see citing works

Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activation

Vecsey, C. G., Hawk, J. D., Lattal, K. M., Stein, J. M., Fabian, S., Attner, M. A., Cabrera, S. M., McDonough, C. B., Brindle, P. K., Abel, T. G., et al. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0296-07.2007 · Cited by 828 · see citing works

Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes

Pandey, R. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf660 · Cited by 783 · see citing works

Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

Radhakrishnan, I., Pérez-Alvarado, G. C., Parker, D., Dyson, H. J., Montminy, M. R., & Wright, P. E. (1997) · Cell · doi:10.1016/s0092-8674(00)80463-8 · Cited by 728 · see citing works

TORCs

Conkright, M. D., Canettieri, G., Screaton, R. A., Guzmán, E., Miraglia, L. J., Hogenesch, J. B., & Montminy, M. (2003) · Molecular Cell · doi:10.1016/j.molcel.2003.08.013 · Cited by 602 · see citing works

CREB: a multifaceted regulator of neuronal plasticity and protection: CREB in synaptic plasticity and cell survival

Sakamoto, K., Karelina, K., & Obrietan, K. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.07080.x · Cited by 543 · see citing works

RNA Helicase A Mediates Association of CBP with RNA Polymerase II

Nakajima, T., Uchida, C., Anderson, S. F., Lee, C.-G., Hurwitz, J., Parvin, J. D., & Montminy, M. (1997) · Cell · doi:10.1016/s0092-8674(00)80376-1 · Cited by 540 · see citing works

The myb gene family in cell growth, differentiation and apoptosis

Oh, I.-H., & Reddy, E. P. (1999) · Oncogene · doi:10.1038/sj.onc.1202839 · Cited by 498 · see citing works

The Transcriptional Coactivator Cbp Interacts with β-Catenin to Activate Gene Expression

Takemaru, K., & Moon, R. T. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.149.2.249 · Cited by 475 · see citing works

CBP: A Signal-Regulated Transcriptional Coactivator Controlled by Nuclear Calcium and CaM Kinase IV

Chawla, S., Hardingham, G. E., Quinn, D. R., & Bading, H. (1998) · Science · doi:10.1126/science.281.5382.1505 · Cited by 427 · see citing works

A Transcriptional Switch Mediated by Cofactor Methylation

Xu, W., Chen, H.-W., Du, K., Asahara, H., Tini, M., Emerson, B. M., Montminy, M., & Evans, R. M. (2001) · Science · doi:10.1126/science.1065961 · Cited by 418 · see citing works

Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

Shimohata, T., Nakajima, T., Yamada, M., Uchida, C., Onodera, O., Naruse, S., Kimura, T., Koide, R., Nozaki, K., Sano, Y., et al. (2000) · Nature Genetics · doi:10.1038/79139 · Cited by 393 · see citing works

Comprehensive review of mechanisms of pathogenesis involved in Alzheimer’s disease and potential therapeutic strategies

Sharma, P., Srivastava, P., Seth, A., Tripathi, P. N., Banerjee, A. G., & Shrivastava, S. K. (2019) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.12.006 · Cited by 331 · see citing works

Regulating gene transcription in response to cyclic AMP elevation

Sands, W. A., & Palmer, T. M. (2007) · Cellular Signalling · doi:10.1016/j.cellsig.2007.10.005 · Cited by 327 · see citing works

Role of Intrinsic Protein Disorder in the Function and Interactions of the Transcriptional Coactivators CREB-binding Protein (CBP) and p300

Dyson, H. J., & Wright, P. E. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.r115.692020 · Cited by 319 · see citing works

Regulation of the steroidogenic acute regulatory protein gene expression: present and future perspectives

Manna, P. R., Dyson, M. T., & Stocco, D. M. (2009) · Molecular Human Reproduction · doi:10.1093/molehr/gap025 · Cited by 315 · see citing works

Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition

Wang, F., Marshall, C. B., & Ikura, M. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1254-4 · Cited by 311 · see citing works

Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: implications for a dominant-negative mechanism

Oike, Y. (1999) · Human Molecular Genetics · doi:10.1093/hmg/8.3.387 · Cited by 306 · see citing works

Regulation of the transcriptional activity of the nuclear factor-κB p65 subunit

Vermeulen, L., Wilde, G. D., Notebaert, S., Berghe, W. V., & Haegeman, G. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)01161-9 · Cited by 304 · see citing works

CREB Transcriptional Activity in Neurons Is Regulated by Multiple, Calcium-Specific Phosphorylation Events

Kornhauser, J. M., Cowan, C. W., Shaywitz, A. J., Dolmetsch, R. E., Griffith, E. C., Hu, L. S., Haddad, C. A., Xia, Z., & Greenberg, M. E. (2002) · Neuron · doi:10.1016/s0896-6273(02)00655-4 · Cited by 292 · see citing works

Association of CBP/p300 Acetylase and Thymine DNA Glycosylase Links DNA Repair and Transcription

Tini, M., Benecke, A., Um, S.-J., Torchia, J., Evans, R. M., & Chambon, P. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00453-7 · Cited by 285 · see citing works

Control of Recruitment and Transcription-Activating Function of CBP Determines Gene Regulation by NMDA Receptors and L-Type Calcium Channels

Hardingham, G. E., Chawla, S., Cruzalegui, F. H., & Bading, H. (1999) · Neuron · doi:10.1016/s0896-6273(00)80737-0 · Cited by 273 · see citing works

CYCLIC AMP SIGNALING AND GENE REGULATION

Daniel, P. B., Walker, W. H., & Habener, J. F. (1998) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.18.1.353 · Cited by 260 · see citing works

Close encounters of the third kind: disordered domains and the interactions of proteins

Tompa, P., Fuxreiter, M., Oldfield, C. J., Simon, I., Dunker, A. K., & Uversky, V. N. (2009) · BioEssays · doi:10.1002/bies.200800151 · Cited by 258 · see citing works

Conformational propensities of intrinsically disordered proteins influence the mechanism of binding and folding

Arai, M., Sugase, K., Dyson, H. J., & Wright, P. E. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1512799112 · Cited by 250 · see citing works

NF-κB activation

Abraham, E. H. (2000) · Critical Care Medicine · doi:10.1097/00003246-200004001-00012 · Cited by 256 · see citing works

The HTLV-1 Tax interactome

Boxus, M., Twizere, J., Legros, S., Dewulf, J.-F., Kettmann, R., & Willems, L. (2008) · Retrovirology · doi:10.1186/1742-4690-5-76 · Cited by 255 · see citing works

The Signal-Dependent Coactivator CBP Is a Nuclear Target for pp90RSK

Nakajima, T., Fukamizu, A., Takahashi, J. B., Gage, F. H., Fisher, T., Blenis, J., & Montminy, M. (1996) · Cell · doi:10.1016/s0092-8674(00)80119-1 · Cited by 254 · see citing works

The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia

Lee, J. T., & McCubrey, J. A. (2002) · Leukemia · doi:10.1038/sj.leu.2402460 · Cited by 249 · see citing works

Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1.

Brass, A. L., Kehrli, E., Eisenbeis, C. F., Storb, U., & Singh, H. (1996) · Genes & Development · doi:10.1101/gad.10.18.2335 · Cited by 242 · see citing works

Analysis of a cAMP-responsive activator reveals a two-component mechanism for transcriptional induction via signal-dependent factors.Preprint

Nakajima, T., Uchida, C., Anderson, S. F., Parvin, J. D., & Montminy, M. (1997) · Genes & Development · doi:10.1101/gad.11.6.738 · Cited by 238 · see citing works

Transcriptional control: Versatile molecular glue

Janknecht, R., & Hunter, T. R. (1996) · Current Biology · doi:10.1016/s0960-9822(02)00636-x · Cited by 230 · see citing works

Regulation of CBP-Mediated Transcription by Neuronal Calcium Signaling

Hu, S., Chrivia, J. C., & Ghosh, A. (1999) · Neuron · doi:10.1016/s0896-6273(00)80738-2 · Cited by 222 · see citing works

Developmental origins of brain disorders: roles for dopamine

Money, K. M., & Stanwood, G. D. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00260 · Cited by 221 · see citing works

Glycogen synthase kinase 3: A point of convergence for the host inflammatory response

Wang, H., Brown, J. R., & Martin, M. (2010) · Cytokine · doi:10.1016/j.cyto.2010.10.009 · Cited by 215 · see citing works

Intrinsically disordered proteins: emerging interaction specialists

Tompa, P., Schád, É., Tantos, Á., & Kalmár, L. (2015) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2015.08.009 · Cited by 215 · see citing works

The cyclic AMP signaling pathway: Exploring targets for successful drug discovery (Review)

Yan, K., GAO, L.-N., Cui, Y., Zhang, Y., & Zhou, X. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5005 · Cited by 215 · see citing works

Epigenetics in the Nervous System: Figure 1.

Jiang, Y., Langley, B. C., Lubin, F. D., Renthal, W. R., Wood, M. A., Yasui, D. H., Kumar, A., Nestler, E. J., Akbarian, S., & Beckel-Mitchener, A. C. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3797-08.2008 · Cited by 214 · see citing works

A Role for CREB Binding Protein and p300 Transcriptional Coactivators in Ets-1 Transactivation Functions

Yang, C., Shapiro, L. H., Rivera, M., Kumar, A., & Brindle, P. K. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.4.2218 · Cited by 211 · see citing works

Assembly requirements of PU.1–Pip (IRF‐4) activator complexes: inhibiting function in vivo using fused dimers

Brass, A. L., Zhu, A. Q., & Singh, H. (1999) · The EMBO Journal · doi:10.1093/emboj/18.4.977 · Cited by 207 · see citing works

Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of c-Myb

Zor, T., Guzman, R. N. D., Dyson, H. J., & Wright, P. E. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.01.038 · Cited by 206 · see citing works

Identification of small-molecule antagonists that inhibit an activator:coactivator interaction

Best, J. L., Amezcua, C. A., Mayr, B. M., Flechner, L., Murawsky, C. M., Emerson, B. M., Zor, T., Gardner, K. H., & Montminy, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406374101 · Cited by 206 · see citing works

CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects

Barco, Á., Pittenger, C., & Kandel, E. R. (2003) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.7.1.101 · Cited by 201 · see citing works

A transcription factor-binding domain of the coactivator CBP is essential for long-term memory and the expression of specific target genesPreprint

Wood, M. A., Attner, M. A., Oliveira, A. M. M., Brindle, P. K., & Abel, T. G. (2006) · Learning & Memory · doi:10.1101/lm.213906 · Cited by 197 · see citing works

AMP-activated Protein Kinase Activation Increases Phosphorylation of Glycogen Synthase Kinase 3β and Thereby Reduces cAMP-responsive Element Transcriptional Activity and Phosphoenolpyruvate Carboxykinase C Gene Expression in the Liver

Horike, N., Sakoda, H., Kushiyama, A., Ono, H., Fujishiro, M., Kamata, H., Nishiyama, K., Uchijima, Y., Kurihara, Y., Kurihara, H., et al. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m802537200 · Cited by 192 · see citing works

A Family of LIM-Only Transcriptional Coactivators: Tissue-Specific Expression and Selective Activation of CREB and CREM

Fimia, G. M., Cesare, D. D., & Sassone‐Corsi, P. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.22.8613-8622.2000 · Cited by 191 · see citing works

Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington’s disease

Ju, T., Chen, H., Lin, J., Chang, C., Chang, W.-C., Kang, J.-J., Sun, C., Tao, M., Tu, P., Chang, C., et al. (2011) · The Journal of Cell Biology · doi:10.1083/jcb.201105010 · Cited by 183 · see citing works

Anchoring of CREB Binding Protein to the Human T-Cell Leukemia Virus Type 1 Promoter: a Molecular Mechanism of Tax Transactivation

Giebler, H. A., Loring, J. E., Orden, K. V., Colgin, M. A., Garrus, J. E., Escudero, K. W., Brauweiler, A. M., & Nyborg, J. K. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.9.5156 · Cited by 179 · see citing works

Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains

Wojciak, J. M., Martinez‐Yamout, M. A., Dyson, H. J., & Wright, P. E. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.30 · Cited by 172 · see citing works

Lysine Acetyltransferases CBP and p300 as Therapeutic Targets in Cognitive and Neurodegenerative Disorders

Valor, L. M., Viosca, J., López‐Atalaya, J. P., & Barco, Á. (2013) · Current Pharmaceutical Design · doi:10.2174/13816128113199990382 · Cited by 168 · see citing works

A CBP/p300 homolog specifies multiple differentiation pathways in Caenorhabditis elegansPreprint

Shi, Y., & Mello, C. C. (1998) · Genes & Development · doi:10.1101/gad.12.7.943 · Cited by 166 · see citing works

Roles of Phosphorylation and Helix Propensity in the Binding of the KIX Domain of CREB-binding Protein by Constitutive (c-Myb) and Inducible (CREB) Activators

Zor, T., Mayr, B. M., Dyson, H. J., Montminy, M., & Wright, P. E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207361200 · Cited by 169 · see citing works

Protein dynamics and function from solution state NMR spectroscopy

Kovermann, M., Rogne, P., & Wolf‐Watz, M. (2016) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583516000019 · Cited by 172 · see citing works

MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype

Hong, Z., Chen, K., Dasgupta, A., Potus, F., Dunham‐Snary, K. J., Bonnet, S., Tian, L., Fu, J. M., Breuils‐Bonnet, S., Provencher, S., et al. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201604-0814oc · Cited by 169 · see citing works

The FHA domain mediates phosphoprotein interactions

Li, J., Lee, G., Doren, S. R. V., & Walker, J. C. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.23.4143 · Cited by 167 · see citing works

Rapid Phosphorylation of Ets-2 Accompanies Mitogen-Activated Protein Kinase Activation and the Induction of Heparin-Binding Epidermal Growth Factor Gene Expression by Oncogenic Raf-1

McCarthy, S. A., Chen, D. W., Yang, B.-S., Garcı́a-Ramı́rez, J. J., Cherwinski, H. M., Chen, X., Klagsbrun, M., Hauser, C. A., Ostrowski, M. C., & McMahon, M. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.5.2401 · Cited by 163 · see citing works

Analysis of an Activator:Coactivator Complex Reveals an Essential Role for Secondary Structure in Transcriptional Activation

Parker, D., Jhala, U. S., Radhakrishnan, I., Yaffe, M. B., Reyes, C., Shulman, A. I., Cantley, L. C., Wright, P. E., & Montminy, M. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80279-8 · Cited by 158 · see citing works

Recruitment of CREB Binding Protein Is Sufficient for CREB-Mediated Gene Activation

Cardinaux, J.-R., Notis, J. C., Zhang, Q., Vo, N., Craig, J. C., Fass, D. M., Brennan, R. G., & Goodman, R. H. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.5.1546-1552.2000 · Cited by 162 · see citing works

Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: roles of reactive oxygen intermediates, NF-kappa B, and cyclic AMP response element binding protein.

Shenkar, R., & Abraham, E. H. (1999) · PubMed · Cited by 148 · see citing works

Conformational preferences in the Ser133‐phosphorylated and non‐phosphorylated forms of the kinase inducible transactivation domain of CREB

Radhakrishnan, I., Pérez-Alvarado, G. C., Dyson, H. J., & Wright, P. E. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00680-2 · Cited by 146 · see citing works

Interactions between the Class II Transactivator and CREB Binding Protein Increase Transcription of Major Histocompatibility Complex Class II Genes

Fontes, J. D., Kanazawa, S., Jean, D., & Peterlin, B. M. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.941 · Cited by 146 · see citing works

Inhibition of host cell transcription by poliovirus: cleavage of transcription factor CREB by poliovirus-encoded protease 3Cpro

Yalamanchili, P., Datta, U., & Dasgupta, A. (1997) · Journal of Virology · doi:10.1128/jvi.71.2.1220-1226.1997 · Cited by 142 · see citing works

p300 Mediates Transcriptional Stimulation by the Basic Helix-Loop-Helix Activators of the Insulin Gene

Qiu, Y., Sharma, A., & Stein, R. W. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.5.2957 · Cited by 140 · see citing works

Interactions with PDZ Proteins Are Required for L-Type Calcium Channels to Activate cAMP Response Element-Binding Protein-Dependent Gene Expression

Weick, J. P., Groth, R. D., Isaksen, A. L., & Mermelstein, P. G. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-08-03446.2003 · Cited by 133 · see citing works

Disordered Proteinaceous Machines

Fuxreiter, M., Tóth-Petróczy, Á., Kraut, D. A., Matouschek, A. T., Lim, R. Y. H., Xue, B., Kurgan, L., & Uversky, V. N. (2014) · Chemical Reviews · doi:10.1021/cr4007329 · Cited by 133 · see citing works

Transcriptional Regulation of the Transforming Growth Factor-β-inducible Mouse Germ Line Ig α Constant Region Gene by Functional Cooperation of Smad, CREB, and AML Family Members

Zhang, Y. E., & Derynck, R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001526200 · Cited by 130 · see citing works

Role of Secondary Structure in Discrimination between Constitutive and Inducible Activators

Parker, D., Rivera, M., Zor, T., Henrion‐Caude, A., Radhakrishnan, I., Kumar, A., Shapiro, L. H., Wright, P. E., Montminy, M., & Brindle, P. K. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.8.5601 · Cited by 129 · see citing works

Mechanisms of Lung Neutrophil Activation After Hemorrhage or Endotoxemia: Roles of Reactive Oxygen Intermediates, NF-κB, and Cyclic AMP Response Element Binding Protein

Shenkar, R., & Abraham, E. H. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.2.954 · Cited by 127 · see citing works

Regulation of inducible gene expression by the transcription factor NF-κB

Ghosh, S. (1999) · Immunologic Research · doi:10.1007/bf02786486 · Cited by 126 · see citing works

Direct Observation of the Dynamic Process Underlying Allosteric Signal Transmission

Brüschweiler, S., Schanda, P., Kloiber, K., Brutscher, B., Kontaxis, G., Konrat, R., & Tollinger, M. (2009) · Journal of the American Chemical Society · doi:10.1021/ja809947w · Cited by 123 · see citing works

Human T-Cell Leukemia Virus Type 1 Tax Requires Direct Access to DNA for Recruitment of CREB Binding Protein to the Viral Promoter

Lenzmeier, B. A., Giebler, H. A., & Nyborg, J. K. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.2.721 · Cited by 122 · see citing works

Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channel by Its R Domain

Ostedgaard, L. S., Baldursson, Ó., & Welsh, M. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.r100001200 · Cited by 121 · see citing works

Regulation of Gene Expression by HTLV-I Tax Protein

Bex, F., & Gaynor, R. B. (1998) · Methods · doi:10.1006/meth.1998.0646 · Cited by 119 · see citing works

Differential Transcriptional Activation by Human T-Cell Leukemia Virus Type 1 Tax Mutants Is Mediated by Distinct Interactions with CREB Binding Protein and p300

Bex, F., Yin, M.-J., Burny, A., & Gaynor, R. B. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.4.2392 · Cited by 119 · see citing works

Coactivation of the CLOCK–BMAL1 complex by CBP mediates resetting of the circadian clock

Lee, Y., Lee, J., Kwon, I., Nakajima, Y., Ohmiya, Y., Son, G. H., Lee, K. H., & Kim, K. (2010) · Journal of Cell Science · doi:10.1242/jcs.070300 · Cited by 118 · see citing works

A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution

Ostedgaard, L. S., Baldursson, Ó., Vermeer, D. W., Welsh, M. J., & Robertson, A. D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.100588797 · Cited by 118 · see citing works

Kinase interaction domain of kinase-associated protein phosphatase, a phosphoprotein-binding domain

Li, J., Smith, G. P., & Walker, J. C. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.14.7821 · Cited by 115 · see citing works

Shaping synaptic plasticity: The role of activity‐mediated epigenetic regulation on gene transcription

Cortés‐Mendoza, J., de León‐Guerrero, S. D., Pedraza‐Alva, G., & Pérez‐Martínez, L. (2013) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2013.04.003 · Cited by 110 · see citing works

Mapping the Interactions of the p53 Transactivation Domain with the KIX Domain of CBP

Lee, C. W., Arai, M., Martinez‐Yamout, M. A., Dyson, H. J., & Wright, P. E. (2009) · Biochemistry · doi:10.1021/bi802055v · Cited by 113 · see citing works

Ca2+‐dependent block of CREB–CBP transcription by repressor DREAM

Ledo, F., Kremer, L., Mellström, B., & Naranjo, J. R. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf440 · Cited by 112 · see citing works

Molecular biology and pathogenesis of the human T‐cell leukaemia/lymphotropic virus Type‐1 (HTLV‐1)

Johnson, J. M., Harrod, R., & Franchini, G. (2001) · International Journal of Experimental Pathology · doi:10.1046/j.1365-2613.2001.00191.x · Cited by 113 · see citing works

Long-Term Treatment with Novel Glycogen Synthase Kinase-3 Inhibitor Improves Glucose Homeostasis in ob/ob Mice: Molecular Characterization in Liver and Muscle

Kaidanovich‐Beilin, O., & Eldar-Finkelman, H. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.105.090266 · Cited by 112 · see citing works

Transcription factor activity of STAT proteins: structural requirements and regulation by phosphorylation and interacting proteins

Decker, T., & Kovarik, P. (1999) · Cellular and Molecular Life Sciences · doi:10.1007/s000180050393 · Cited by 110 · see citing works

Binding of p53 to the KIX Domain of CREB Binding Protein

Orden, K. V., Giebler, H. A., Lemasson, I., Gonzales, M. S., & Nyborg, J. K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.37.26321 · Cited by 110 · see citing works

Dual Roles of RNA Helicase A in CREB-Dependent Transcription

Aratani, S., Fujii, R., Oishi, T., Fujita, H., Amano, T., Ohshima, T., Hagiwara, M., Fukamizu, A., & Nakajima, T. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.14.4460-4469.2001 · Cited by 108 · see citing works

Molecular recognition by the KIX domain and its role in gene regulation

Thakur, J. K., Yadav, A., & Yadav, G. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1147 · Cited by 109 · see citing works

Energy Landscapes of Protein Aggregation and Conformation Switching in Intrinsically Disordered Proteins

Strodel, B. (2021) · Journal of Molecular Biology · doi:10.1016/j.jmb.2021.167182 · Cited by 104 · see citing works

Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction

Uttarkar, S., Dassé, E., Coulibaly, A., Steinmann, S., Jakobs, A., Schomburg, C., Trentmann, A., Jose, J., Schlenke, P., Berdel, W. E., et al. (2015) · Blood · doi:10.1182/blood-2015-09-668632 · Cited by 104 · see citing works

Magnitude of the CREB-Dependent Transcriptional Response Is Determined by the Strength of the Interaction between the Kinase-Inducible Domain of CREB and the KIX Domain of CREB-Binding Protein

Michael, & Greenberg, E. (2000)

Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

Radhakrishnan, I., Pérez-Alvarado, G. C., Parker, D., Dyson, H. J., Montminy, M. R., & Wright, P. E. (1997) · Cell · doi:10.1016/s0092-8674(00)80463-8 · Cited by 728 · see citing works

Phosphorylation‐induced transient intrinsic structure in the kinase‐inducible domain of CREB facilitates its recognition by the KIX domain of CBP

Solt, I., Magyar, C., Simon, I., Tompa, P., & Fuxreiter, M. (2006) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.21032 · Cited by 40 · see citing works

Analysis of an Activator:Coactivator Complex Reveals an Essential Role for Secondary Structure in Transcriptional Activation

Parker, D., Jhala, U. S., Radhakrishnan, I., Yaffe, M. B., Reyes, C., Shulman, A. I., Cantley, L. C., Wright, P. E., & Montminy, M. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80279-8 · Cited by 158 · see citing works

Roles of Phosphorylation and Helix Propensity in the Binding of the KIX Domain of CREB-binding Protein by Constitutive (c-Myb) and Inducible (CREB) Activators

Zor, T., Mayr, B. M., Dyson, H. J., Montminy, M., & Wright, P. E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207361200 · Cited by 169 · see citing works