Evans, Ronald M.

Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes

Uhlenhaut, N. H., Barish, G. D., Yu, R. T., Downes, M., Karunasiri, M., Liddle, C., Schwalie, P., Hübner, N., & Evans, R. M. (2013) · Molecular Cell

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 265

Regulation of MEF2 by Histone Deacetylase 4- and SIRT1 Deacetylase-Mediated Lysine Modifications

Zhao, X., Sternsdorf, T., Bolger, T. A., Evans, R. M., & Yao, T.-P. (2005) · Molecular and Cellular Biology

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 264

PPARγ activation in adipocytes is sufficient for systemic insulin sensitization

Sugii, S., Olson, P., Sears, D. D., Saberi, M., Atkins, A. R., Barish, G. D., Hong, S.-H., Castro, G. L., Yin, Y.-Q., Nelson, M. C., et al. (2009) · Proceedings of the National Academy of Sciences

Peroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases

Cited by 255

The Constitutive Androstane Receptor and Pregnane X Receptor Function Coordinately to Prevent Bile Acid-induced Hepatotoxicity

Zhang, J., Huang, W., Qatanani, M., Evans, R. M., & Moore, D. D. (2004) · Journal of Biological Chemistry

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 246

BRD4 is a novel therapeutic target for liver fibrosis

Ding, N., Hah, N., Yu, R. T., Sherman, M. H., Benner, C., Leblanc, M., He, M., Liddle, C., Downes, M., & Evans, R. M. (2015) · Proceedings of the National Academy of Sciences

Liver physiology and pathologyProtein Degradation and Inhibitors

Cited by 211

Orphan Nuclear Receptors: The Exotics of Xenobiotics

Xie, W., & Evans, R. M. (2001) · Journal of Biological Chemistry

Pharmacogenetics and Drug MetabolismNuclear Receptors and Signaling

Cited by 210

PPARδ Promotes Running Endurance by Preserving Glucose

Fan, W., Waizenegger, W., Lin, C. S., Sorrentino, V., He, M.-X., Wall, C. E., Li, H., Liddle, C., Yu, R. T., Atkins, A. R., et al. (2017) · Cell Metabolism

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 198

Isolation and Characterization of Mammalian HDAC10, a Novel Histone Deacetylase

Kao, H.-Y., Lee, C.-H., Komarov, A., Han, C. C., & Evans, R. M. (2002) · Journal of Biological Chemistry

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 193

Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling

Schieber, A. M. P., Lee, Y. M., Chang, M. W., Leblanc, M., Collins, B., Downes, M., Evans, R. M., & Ayres, J. S. (2015) · Science

Gut microbiota and healthImmune Response and Inflammation

Cited by 189

Exercise Mimetics: Impact on Health and Performance

Fan, W., & Evans, R. M. (2017) · Cell Metabolism

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 188

Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation

Xia, W., Veeragandham, P., Cao, Y., Xu, Y., Rhyne, T. E., Qian, J., Hung, C.-W., Zhao, P., Jones, Y., Gao, H., et al. (2024) · Nature Metabolism

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 176

Characterization of Distinct Subpopulations of Hepatic Macrophages in HFD/Obese Mice

Morinaga, H., Mayoral, R., Heinrichsdorff, J., Osborn, O., Franck, N., Hah, N., Walenta, E., Bandyopadhyay, G., Pessentheiner, A. R., Chi, T. J., et al. (2015) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesLiver physiology and pathology

Cited by 175

Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist

Iwaisako, K., Haimerl, M., Paik, Y.-H., Taura, K., Kodama, Y., Sirlin, C., Yu, E., Yu, R. T., Downes, M., Evans, R. M., et al. (2012) · Proceedings of the National Academy of Sciences

Peroxisome Proliferator-Activated ReceptorsLiver physiology and pathology

Cited by 157

Nuclear Receptors in Sicily: All in the Famiglia

Perlmann, T., & Evans, R. M. (1997) · Cell

Estrogen and related hormone effectsNuclear Receptors and Signaling

Cited by 148

Stromal cues regulate the pancreatic cancer epigenome and metabolome

Sherman, M. H., Yu, R. T., Tseng, T. W., Sousa, C. M., Liu, S., Truitt, M. L., He, N., Ding, N., Liddle, C., Atkins, A. R., et al. (2017) · Proceedings of the National Academy of Sciences

Pancreatic and Hepatic Oncology ResearchCancer Cells and Metastasis

Cited by 147

Cytoplasmic catalytic subunit of protein kinase A mediates cross-repression by NF-κB and the glucocorticoid receptor

Doucas, V., Shi, Y., Miyamoto, S., West, A., Verma, I., & Evans, R. M. (2000) · Proceedings of the National Academy of Sciences

NF-κB Signaling PathwaysEstrogen and related hormone effects

Cited by 125

Peroxisome proliferator-activated receptor δ promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage

Lee, C.-H., Kang, K., Mehl, I. R., Nofsinger, R., Alaynick, W. A., Chong, L.-W., Rosenfeld, J. M., & Evans, R. M. (2006) · Proceedings of the National Academy of Sciences

Peroxisome Proliferator-Activated ReceptorsCholesterol and Lipid Metabolism

Cited by 98

The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages

Daniel, B., Nagy, G., Hah, N., Horvath, A., Czimmerer, Z., Poliska, S., Gyuris, T., Keirsse, J., Gysemans, C., Van Ginderachter, J. A., et al. (2014) · Genes & Development

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 97

Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma

Liu, H., Naxerova, K., Pinter, M., Incio, J., Lee, H., Shigeta, K., Ho, W. W., Crain, J. A., Jacobson, A., Michelakos, T., et al. (2017) · Clinical Cancer Research

Pancreatic and Hepatic Oncology ResearchPeptidase Inhibition and Analysis

Cited by 96

Tumor suppressor protein (p)53, is a regulator of NF-κB repression by the glucocorticoid receptor

Murphy, S. H., Suzuki, K., Downes, M., Welch, G. L., De Jesus, P., Miraglia, L. J., Orth, A. P., Chanda, S. K., Evans, R. M., & Verma, I. M. (2011) · Proceedings of the National Academy of Sciences

NF-κB Signaling PathwaysEstrogen and related hormone effects

Cited by 93

Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism

Pei, L., Mu, Y., Leblanc, M., Alaynick, W., Barish, G. D., Pankratz, M., Tseng, T. W., Kaufman, S., Liddle, C., Yu, R. T., et al. (2015) · Cell Metabolism

Neuroscience and Neuropharmacology ResearchMitochondrial Function and Pathology

Cited by 65

Loss of transcriptional repression by BCL6 confers insulin sensitivity in the setting of obesity

Senagolage, M. D., Sommars, M. A., Ramachandran, K., Futtner, C. R., Omura, Y., Allred, A. L., Wang, J., Yang, C., Procissi, D., Evans, R. M., et al. (2018) · Cell Reports

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 44