Pascolo, Steve

Direct Injection of Protamine-protected mRNA: Results of a Phase 1/2 Vaccination Trial in Metastatic Melanoma Patients

Weide, B., Pascolo, S., Scheel, B., Derhovanessian, E., Pflugfelder, A., Eigentler, T. K., Pawelec, G., Hoerr, I., Rammensee, H.-G., & Garbe, C. (2009) · Journal of Immunotherapy

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 378

Results of the First Phase I/II Clinical Vaccination Trial With Direct Injection of mRNA

Weide, B., Carralot, J.-P., Reese, A., Scheel, B., Eigentler, T. K., Hoerr, I., Rammensee, H.-G., Garbe, C., & Pascolo, S. (2008) · Journal of Immunotherapy

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 261

Intradermal Vaccinations With RNA Coding for TAA Generate CD8+ and CD4+ Immune Responses and Induce Clinical Benefit in Vaccinated Patients

Rittig, S. M., Haentschel, M., Weimer, K. J., Heine, A., Muller, M. R., Brugger, W., Horger, M. S., Maksimovic, O., Stenzl, A., Hoerr, I., et al. (2011) · Molecular Therapy

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 226

Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent

Probst, J., Weide, B., Scheel, B., Pichler, B. J., Hoerr, I., Rammensee, H.-G., & Pascolo, S. (2007) · Gene Therapy

RNA Interference and Gene DeliveryRNA and protein synthesis mechanisms

Cited by 206

Messenger RNA-based vaccines

Pascolo, S. (2004) · Expert Opinion on Biological Therapy

RNA Interference and Gene DeliveryImmunotherapy and Immune Responses

Cited by 152

Polarization of immunity induced by direct injection of naked sequence-stabilized mRNA vaccines

Carralot, J.-P., Probst, J., Hoerr, I., Scheel, B., Teufel, R., Jung, G., Rammensee, H.-G., & Pascolo, S. (2004) · Cellular and Molecular Life Sciences CMLS

Immunotherapy and Immune ResponsesRNA Interference and Gene Delivery

Cited by 149

Vaccination with Messenger RNA (mRNA)

Pascolo, S. (2008) · Handbook of Experimental Pharmacology

Immunotherapy and Immune ResponsesRNA Interference and Gene Delivery

Cited by 126

Protamine-Based Strategies for RNA Transfection

Jarzebska, N. T., Mellett, M., Frei, J., Kündig, T. M., & Pascolo, S. (2021) · Pharmaceutics

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 95

Characterization of the ribonuclease activity on the skin surface

Probst, J., Brechtel, S., Scheel, B., Hoerr, I., Jung, G., Rammensee, H.-G., & Pascolo, S. (2006) · Genetic Vaccines and Therapy

RNA Interference and Gene DeliveryRNA Research and Splicing

Cited by 84

Gemcitabine depletes regulatory T‐cells in human and mice and enhances triggering of vaccine‐specific cytotoxic T‐cells

Rettig, L., Seidenberg, S., Parvanova, I., Samaras, P., Knuth, A., & Pascolo, S. (2011) · International Journal of Cancer

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 83

Promiscuous survivin peptide induces robust CD4+ T‐cell responses in the majority of vaccinated cancer patients

Widenmeyer, M., Griesemann, H., Stevanović, S., Feyerabend, S., Klein, R., Attig, S., Hennenlotter, J., Wernet, D., Kuprash, D. V., Sazykin, A. Y., et al. (2012) · International Journal of Cancer

Immunotherapy and Immune Responsesvaccines and immunoinformatics approaches

Cited by 70

Human peripheral blood monuclear cells transfected with messenger RNA stimulate antigen-specific cytotoxic T-lymphocytes in vitro

Teufel, R., Carralot, J.-P., Scheel, B., Probst, J., Walter, S., Jung, G., Hoerr, I., Rammensee, H.-G., & Pascolo, S. (2005) · Cellular and Molecular Life Sciences

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 22