Loane, David J.

The far-reaching scope of neuroinflammation after traumatic brain injury

Simon, D. W., McGeachy, M. J., Bayır, H., Clark, R. S. B., Loane, D. J., & Kochanek, P. M. (2017) · Nature Reviews Neurology

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 1,190

Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention

Kumar, A., & Loane, D. J. (2012) · Brain, Behavior, and Immunity

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 710

Role of Microglia in Neurotrauma

Loane, D. J., & Byrnes, K. R. (2010) · Neurotherapeutics

Neuroinflammation and Neurodegeneration MechanismsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 657

Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

Loane, D. J., & Faden, A. I. (2010) · Trends in Pharmacological Sciences

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 574

Progressive Neurodegeneration After Experimental Brain Trauma: Association With Chronic Microglial Activation

Loane, D. J., Kumar, A., Stoica, B. A., Cabatbat, R., & Faden, A. I. (2014) · Journal of Neuropathology & Experimental Neurology

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 498

Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury

Kumar, A., Alvarez-Croda, D.-M., Stoica, B. A., Faden, A. I., & Loane, D. J. (2016) · Journal of Neurotrauma

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 339

Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury

Loane, D. J., Pocivavsek, A., Moussa, C. E.-H., Thompson, R., Matsuoka, Y., Faden, A. I., Rebeck, G. W., & Burns, M. P. (2009) · Nature Medicine

Traumatic Brain Injury and Neurovascular DisturbancesAlzheimer's disease research and treatments

Cited by 246

Chronic Neurodegeneration After Traumatic Brain Injury: Alzheimer Disease, Chronic Traumatic Encephalopathy, or Persistent Neuroinflammation?

Faden, A. I., & Loane, D. J. (2015) · Neurotherapeutics

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 245

Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states

Kumar, A., Stoica, B. A., Sabirzhanov, B., Burns, M. P., Faden, A. I., & Loane, D. J. (2013) · Neurobiology of Aging

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 244

NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury

Kumar, A., Barrett, J. P., Alvarez-Croda, D.-M., Stoica, B. A., Faden, A. I., & Loane, D. J. (2016) · Brain Behavior and Immunity

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 213

Erratum: The far-reaching scope of neuroinflammation after traumatic brain injury

Simon, D. W., McGeachy, M. J., Bayır, H., Clark, R. S. B., Loane, D. J., & Kochanek, P. M. (2017) · Nature Reviews Neurology

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 160

Old age increases microglial senescence, exacerbates secondary neuroinflammation, and worsens neurological outcomes after acute traumatic brain injury in mice

Ritzel, R. M., Doran, S. J., Glaser, E. P., Meadows, V. E., Faden, A. I., Stoica, B. A., & Loane, D. J. (2019) · Neurobiology of Aging

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 156

Controlled Cortical Impact Results in an Extensive Loss of Dendritic Spines that Is Not Mediated by Injury-Induced Amyloid-Beta Accumulation

Winston, C. N., Chellappa, D., Wilkins, T., Barton, D. J., Washington, P. M., Loane, D. J., Zapple, D. N., & Burns, M. P. (2013) · Journal of Neurotrauma

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 84

Modulation of ABCA1 by an LXR Agonist Reduces Beta-Amyloid Levels and Improves Outcome after Traumatic Brain Injury

Loane, D. J., Washington, P. M., Vardanian, L., Pocivavsek, A., Hoe, H.-S., Duff, K. E., Cernak, I., Rebeck, G. W., Faden, A. I., & Burns, M. P. (2011) · Journal of Neurotrauma

Traumatic Brain Injury and Neurovascular DisturbancesAlzheimer's disease research and treatments

Cited by 57

Inflammatory response of microglia to prions is controlled by sialylation of PrPSc

Srivastava, S., Katorcha, E., Makarava, N., Barrett, J. P., Loane, D. J., & Baskakov, I. V. (2018) · Scientific Reports

Prion Diseases and Protein MisfoldingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 47

CD38 knockout mice show significant protection against ischemic brain damage despite high level poly-ADP-ribosylation

Long, A., Park, J. H., Klimova, N., Fowler, C., Loane, D. J., & Kristian, T. (2017) · Neurochemical Research

Sirtuins and Resveratrol in MedicineNeuroprotection in Cerebral Ischemia

Cited by 44