Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury

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Inhibition of NADPH Oxidase is Neuroprotective after Ischemia—Reperfusion

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Repeated Mild Traumatic Brain Injury Causes Chronic Neuroinflammation, Changes in Hippocampal Synaptic Plasticity, and Associated Cognitive Deficits

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CCR2 antagonism alters brain macrophage polarization and ameliorates cognitive dysfunction induced by traumatic brain injury

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Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury

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Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states

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Temporal Changes in Cell Marker Expression and Cellular Infiltration in a Controlled Cortical Impact Model in Adult Male C57BL/6 Mice

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Critical Role of NADPH Oxidase in Neuronal Oxidative Damage and Microglia Activation following Traumatic Brain Injury

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The neuroinflammatory response in humans after traumatic brain injury

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IL-4 Signaling Drives a Unique Arginase+/IL-1 + Microglia Phenotype and Recruits Macrophages to the Inflammatory CNS: Consequences of Age-Related Deficits in IL-4R  after Traumatic Spinal Cord Injury

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Long-Term Upregulation of Inflammation and Suppression of Cell Proliferation in the Brain of Adult Rats Exposed to Traumatic Brain Injury Using the Controlled Cortical Impact Model

Acosta, S. A., Tajiri, N., Shinozuka, K., Ishikawa, H., Grimmig, B. A., Diamond, D. M., Sanberg, P. R., Bickford, P. C., Kaneko, Y., & Borlongan, C. V. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053376 · Cited by 194 · see citing works

Neuroinflammatory phenotype in early Alzheimer's disease

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Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury

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Traumatic brain injury induces macrophage subsets in the brain

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Prolonged Activation of NF-κB Following Traumatic Brain Injury in Rats

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CCR2 deficiency impairs macrophage infiltration and improves cognitive function after traumatic brain injury

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Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury

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Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry

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Macrophagic and microglial responses after focal traumatic brain injury in the female rat

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Prolonged Microgliosis in the Rhesus Monkey Central Nervous System after Traumatic Brain Injury

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NADPH Oxidase-Mediated Triggering of Inflammasome Activation in Mouse Podocytes and Glomeruli During Hyperhomocysteinemia

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Prevention of traumatic brain injury-induced neuronal death by inhibition of NADPH oxidase activation

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Repair of Oxidative DNA Damage, Cell-Cycle Regulation and Neuronal Death May Influence the Clinical Manifestation of Alzheimer’s Disease

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Activation of mGluR5 and Inhibition of NADPH Oxidase Improves Functional Recovery after Traumatic Brain Injury

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Selective CDK Inhibitor Limits Neuroinflammation and Progressive Neurodegeneration after Brain Trauma

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Relationship of nitric oxide synthase induction to peroxynitrite-mediated oxidative damage during the first week after experimental traumatic brain injury

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Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid deposition in APP/PS1 transgenic mice

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Interacting Chemokine Signals Regulate Dendritic Cells in Acute Brain Injury

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Neuroinflammation: The Devil Is in the Details

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Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift

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Microglial Activation in Traumatic Brain Injury

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NADPH oxidase in brain injury and neurodegenerative disorders

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Advanced oxidation protein products induce microglia-mediated neuroinflammation via MAPKs-NF-κB signaling pathway and pyroptosis after secondary spinal cord injury

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Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis.

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Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury

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Microglia Phenotypes in Aging and Neurodegenerative Diseases

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Microglial Depletion with CSF1R Inhibitor During Chronic Phase of Experimental Traumatic Brain Injury Reduces Neurodegeneration and Neurological Deficits

Henry, R. J., Ritzel, R. M., Barrett, J. P., Doran, S. J., Jiao, Y., Leach, J. B., Szeto, G. L., Wu, J., Stoica, B. A., Faden, A. I., et al. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.2402-19.2020 · Cited by 333 · see citing works

Sexual dimorphism in the inflammatory response to traumatic brain injury

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Microglia and macrophage metabolism in CNS injury and disease: The role of immunometabolism in neurodegeneration and neurotrauma

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The roles of macrophages and microglia in multiple sclerosis and experimental autoimmune encephalomyelitis

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Response of the cerebral vasculature following traumatic brain injury

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Cellular infiltration in traumatic brain injury

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MicroRNAs: Roles in Regulating Neuroinflammation

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Omega-3 polyunsaturated fatty acid attenuates the inflammatory response by modulating microglia polarization through SIRT1-mediated deacetylation of the HMGB1/NF-κB pathway following experimental traumatic brain injury

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Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury

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Microglia and Neuroinflammation: Crucial Pathological Mechanisms in Traumatic Brain Injury-Induced Neurodegeneration

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Neuroinflammation in animal models of traumatic brain injury

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Current understanding of neuroinflammation after traumatic brain injury and cell-based therapeutic opportunities

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Anti-inflammatory and immunomodulatory mechanisms of atorvastatin in a murine model of traumatic brain injury

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Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration

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The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments

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A Review of the Molecular Mechanisms of Traumatic Brain Injury

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NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury

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Pharmacological Modulation of Functional Phenotypes of Microglia in Neurodegenerative Diseases

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Sex Differences in Acute Neuroinflammation after Experimental Traumatic Brain Injury Are Mediated by Infiltrating Myeloid Cells

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SIRT1 Promotes M2 Microglia Polarization via Reducing ROS-Mediated NLRP3 Inflammasome Signaling After Subarachnoid Hemorrhage

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mTORC1 pathway disruption ameliorates brain inflammation following stroke via a shift in microglia phenotype from M1 type to M2 type

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Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes

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Brain trauma elicits non-canonical macrophage activation states

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Distinct myeloid cell subsets promote meningeal remodeling and vascular repair after mild traumatic brain injury

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Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration

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Microglial metabolic disturbances and neuroinflammation in cerebral infarction

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The Polarization States of Microglia in TBI: A New Paradigm for Pharmacological Intervention

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Loss of IL-10 Promotes Differentiation of Microglia to a M1 Phenotype

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Neuroinflammation Following Traumatic Brain Injury: Take It Seriously or Not

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Time-Dependent Changes in Microglia Transcriptional Networks Following Traumatic Brain Injury

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Polarization of Microglia to the M2 Phenotype in a Peroxisome Proliferator-Activated Receptor Gamma–Dependent Manner Attenuates Axonal Injury Induced by Traumatic Brain Injury in Mice

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M-CSF, IL-6, and TGF-β promote generation of a new subset of tissue repair macrophage for traumatic brain injury recovery

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Does neuroinflammation drive the relationship between tau hyperphosphorylation and dementia development following traumatic brain injury?

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The role of NOX inhibitors in neurodegenerative diseases

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NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury

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Central Nervous System Injury and Nicotinamide Adenine Dinucleotide Phosphate Oxidase: Oxidative Stress and Therapeutic Targets

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Novel microglia-mediated mechanisms underlying synaptic loss and cognitive impairment after traumatic brain injury

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Neuroinflammation in Ischemic Stroke: Focus on MicroRNA-mediated Polarization of Microglia

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Inhibition of miR-155 Limits Neuroinflammation and Improves Functional Recovery After Experimental Traumatic Brain Injury in Mice

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Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain

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Protection of Brain Injury by Amniotic Mesenchymal Stromal Cell-Secreted Metabolites

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Knowledge Gaps and Emerging Research Areas in Intrauterine Growth Restriction-Associated Brain Injury

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Microglia Receptors in Animal Models of Traumatic Brain Injury

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Role of dietary phenols in mitigating microglia-mediated neuroinflammation

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Acute colitis during chronic experimental traumatic brain injury in mice induces dysautonomia and persistent extraintestinal, systemic, and CNS inflammation with exacerbated neurological deficits

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TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation

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Microglial cell‐derived interleukin‐6 influences behavior and inflammatory response in the brain following traumatic brain injury

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ORIGINAL ARTICLE Microglia/macrophage polarization dynamics in white matter

(2016)

NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury

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Call off the dog(ma): M1/M2 polarization is concurrent following traumatic brain injury

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Regulatory role of NADPH oxidase 2 in the polarization dynamics and neurotoxicity of microglia/macrophages after traumatic brain injury

Wang, J., Ma, M. W., Dhandapani, K. M., & Brann, D. W. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.09.017 · Cited by 68 · see citing works