Jacobson, Laura H.

Induction of cerebral β-amyloidosis: Intracerebral versus systemic Aβ inoculation

Eisele, Y. S., Bolmont, T., Heikenwalder, M., Langer, F., Jacobson, L. H., Yan, Z.-X., Roth, K., Aguzzi, A., Staufenbiel, M., Walker, L. C., et al. (2009) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 279

Default Mode Network Modulation by Psychedelics: A Systematic Review

Gattuso, J. J., Perkins, D., Ruffell, S., Lawrence, A. J., Hoyer, D., Jacobson, L. H., Timmermann, C., Castle, D., Rossell, S. L., Downey, L. A., et al. (2023) · International Journal of Neuropsychopharmacology

Psychedelics and Drug StudiesFunctional Brain Connectivity Studies

Cited by 256

The BACE‐1 inhibitor CNP520 for prevention trials in Alzheimer's disease

Neumann, U., Ufer, M., Jacobson, L. H., Rouzade‐Dominguez, M., Huledal, G., Kolly, C., Lüönd, R. M., Machauer, R., Veenstra, S. J., Hurth, K., et al. (2018) · EMBO Molecular Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 177

mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity

Fendt, M., Schmid, S., Thakker, D. R., Jacobson, L. H., Yamamoto, R., Mitsukawa, K., Maier, R., Natt, F., Hüsken, D., Kelly, P. H., et al. (2008) · Molecular Psychiatry

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 135

A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice.

Neumann, U., Rueeger, H., Machauer, R., Veenstra, S. J., Lueoend, R. M., Tintelnot-Blomley, M., Laue, G., Beltz, K., Vogg, B., Schmid, P., et al. (2015) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative Diseases

Cited by 113

Discovery of Umibecestat (CNP520): A Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor for the Prevention of Alzheimer’s Disease

Machauer, R., Lueoend, R., Hurth, K., Veenstra, S. J., Rueeger, H., Voegtle, M., Tintelnot-Blomley, M., Rondeau, J.-M., Jacobson, L. H., Laue, G., et al. (2021) · Journal of Medicinal Chemistry

Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative Diseases

Cited by 40