Deng, Hongkui

Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds.

Hou, P., Li, Y., Zhang, X., Liu, C., Guan, J., Li, H., Zhao, T., Ye, J., Yang, W., Liu, K., et al. (2013) · Science

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 1,402

Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells

Song, Z., Cai, J., Liu, Y., Zhao, D., Yong, J., Duo, S., Song, X., Guo, Y., Zhao, Y., Qin, H., et al. (2009) · Cell Research

Pluripotent Stem Cells ResearchMesenchymal stem cell research

Cited by 499

Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation

Zhao, Y., Yin, X., Qin, H., Zhu, F., Liu, H., Yang, W., Zhang, Q., Xiang, C., Hou, P., Song, Z., et al. (2008) · Cell Stem Cell

Pluripotent Stem Cells ResearchMesenchymal stem cell research

Cited by 468

CRISPR-Edited Stem Cells in a Patient with HIV and Acute Lymphocytic Leukemia

Xu, L., Wang, J., Liu, Y., Xie, L., Su, B., Mou, D., Wang, L., Liu, T., Wang, X., Zhang, B., et al. (2019) · New England Journal of Medicine

CRISPR and Genetic EngineeringCAR-T cell therapy research

Cited by 454

Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons.

Li, X., Zuo, X., Jing, J., Ma, Y., Wang, J., Liu, D., Zhu, J., Du, X., Xiong, L., Du, Y., et al. (2015) · Cell Stem Cell

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 428

Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice

Cai, Y., Zhou, H., Zhu, Y., Sun, Q., Ji, Y., Xue, A., Wang, Y., Chen, W., Yu, X., Wang, L., et al. (2020) · Cell Research

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 397

Chemical reprogramming of human somatic cells to pluripotent stem cells.

Guan, J., Wang, G., Wang, J., Zhang, Z., Fu, Y., Cheng, L., Meng, G., Lyu, Y., Zhu, J., Li, Y., et al. (2022) · Nature

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 388

Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming

Du, Y., Wang, J., Jia, J., Song, N., Xiang, C., Xu, J., Hou, Z., Su, X., Liu, B., Jiang, T., et al. (2014) · Cell Stem Cell

Pluripotent Stem Cells ResearchLiver physiology and pathology

Cited by 320

Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient.

Wang, S., Du, Y., Zhang, B., Meng, G., Liu, Z., Liew, S. Y., Liang, R., Zhang, Z., Cai, X., Wu, S., et al. (2024) · Cell

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 281

Long-term functional maintenance of primary human hepatocytes in vitro

Xiang, C., Du, Y., Meng, G., Soon Yi, L., Sun, S., Song, N., Zhang, X., Xiao, Y., Wang, J., Yi, Z., et al. (2019) · Science

Hepatitis B Virus StudiesLiver physiology and pathology

Cited by 223

Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates

Du, Y., Liang, Z., Wang, S., Sun, D., Wang, X., Liew, S. Y., Lu, S., Wu, S., Jiang, Y., Wang, Y., et al. (2022) · Nature Medicine

Pancreatic function and diabetesPluripotent Stem Cells Research

Cited by 155

Establishment of intestinal organoid cultures modeling injury-associated epithelial regeneration

Qu, M., Xiong, L., Lyu, Y., Zhang, X., Shen, J., Guan, J., Chai, P., Lin, Z., Nie, B., Li, C., et al. (2021) · Cell Research

Wnt/β-catenin signaling in development and cancerDigestive system and related health

Cited by 138

Highly efficient and rapid generation of human pluripotent stem cells by chemical reprogramming.

Liuyang, S., Wang, G., Wang, Y., He, H., Lyu, Y., Cheng, L., Yang, Z., Guan, J., Fu, Y., Zhu, J., et al. (2023) · Cell Stem Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 136

Chemical reprogramming for cell fate manipulation: Methods, applications, and perspectives

Wang, J., Sun, S., & Deng, H. (2023) · Cell Stem Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 91

Implantation underneath the abdominal anterior rectus sheath enables effective and functional engraftment of stem-cell-derived islets

Liang, Z., Sun, D., Lu, S., Lei, Z., Wang, S., Luo, Z., Zhan, J., Wu, S., Jiang, Y., Lu, Z., et al. (2023) · Nature Metabolism

Pancreatic function and diabetesPluripotent Stem Cells Research

Cited by 59

Bioprinting functional hepatocyte organoids derived from human chemically induced pluripotent stem cells to treat liver failure.

Li, G., He, J., Shi, J., Li, X., Liu, L., Ge, X., Chen, W., Jia, J., Wang, J., Yin, M., et al. (2025) · Gut

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 41

A two-step strategy to expand primary human hepatocytes in vitro with efficient metabolic and regenerative capacities

Xie, H., Li, G., Fu, Y., Jiang, N., Yi, S., Kong, X., Shi, J., Yin, S., Peng, J., Jiang, Y., et al. (2024) · Stem Cell Research & Therapy

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 9