Chan, Catherine B.

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β-cell dysfunction, and type 2 diabetes.

Zhang, C.-Y., Baffy, G., Perret, P., Krauss, S., Peroni, O., Grujic, D., Hagen, T., Vidal-Puig, A. J., Boss, O., Kim, Y.-B., et al. (2001) · Cell

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 917

Increased Uncoupling Protein-2 Levels in β-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion

Chan, C. B., De Leo, D., Joseph, J. W., McQuaid, T. S., Ha, X. F., Xu, F., Tsushima, R. G., Pennefather, P. S., Salapatek, A. M. F., & Wheeler, M. B. (2001) · Diabetes

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 341

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

Chan, C. B., MacDonald, P. E., Saleh, M. C., Johns, D. C., Marbàn, E., & Wheeler, M. B. (1999) · Diabetes

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 242

Uncoupling Protein 2 Knockout Mice Have Enhanced Insulin Secretory Capacity After a High-Fat Diet

Joseph, J. W., Koshkin, V., Zhang, C.-Y., Wang, J., Lowell, B. B., Chan, C. B., & Wheeler, M. B. (2002) · Diabetes

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 220

Free Fatty Acid-induced β-Cell Defects Are Dependent on Uncoupling Protein 2 Expression

Joseph, J. W., Koshkin, V., Saleh, M. C., Sivitz, W. I., Zhang, C.-Y., Lowell, B. B., Chan, C. B., & Wheeler, M. B. (2004) · Journal of Biological Chemistry

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 206

Nutrition Therapy

Sievenpiper, J. L., Chan, C. B., Dworatzek, P. D., Freeze, C., & Williams, S. L. (2018) · Canadian Journal of Diabetes

Diabetes Management and EducationDiabetes Management and Research

Cited by 200

Mitochondrial functional state in clonal pancreatic β-cells exposed to free fatty acids.

Koshkin, V., Wang, X., Scherer, P. E., Chan, C. B., & Wheeler, M. B. (2003) · Journal of Biological Chemistry

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 121

Dietary Patterns and Cardiovascular Disease Risk in People with Type 2 Diabetes

Archundia Herrera, M. C., Subhan, F. B., & Chan, C. B. (2017) · Current Obesity Reports

Nutritional Studies and DietDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 98

Dietary pea fiber supplementation improves glycemia and induces changes in the composition of gut microbiota, serum short chain fatty acid profile and expression of mucins in glucose intolerant rats

Hashemi, Z., Fouhse, J., Im, H., Chan, C., & Willing, B. (2017) · Nutrients

Gut microbiota and healthFood composition and properties

Cited by 70