Ueki, Kohjiro

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Yamauchi, T., Kamon, J., Minokoshi, Y., Ito, Y., Waki, H., Uchida, S., Yamashita, S., Noda, M., Kita, S., Ueki, K., et al. (2002) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesMetabolism, Diabetes, and Cancer

Cited by 4,238

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

Nishimura, S., Manabe, I., Nagasaki, M., Eto, K., Yamashita, H., Ohsugi, M., Otsu, M., Hara, K., Ueki, K., Sugiura, S., et al. (2009) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 2,230

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

Yamauchi, T., Nio, Y., Maki, T., Kobayashi, M., Takazawa, T., Iwabu, M., Okada-Iwabu, M., Kawamoto, S., Kubota, N., Kubota, T., et al. (2007) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesPeroxisome Proliferator-Activated Receptors

Cited by 1,396

Adiponectin and AdipoR1 Regulate PGC-1α and Mitochondria by Ca2+ and AMPK/SIRT1

Iwabu, M., Yamauchi, T., Okada-Iwabu, M., Sato, K., Nakagawa, T., Funata, M., Yamaguchi, M., Namiki, S., Nakayama, R., Tabata, M., et al. (2010) · Nature

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 971

Protein–protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

Virkamäki, A., Ueki, K., & Kahn, C. R. (1999) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 854

Adiponectin Stimulates AMP-Activated Protein Kinase in the Hypothalamus and Increases Food Intake

Kubota, N., Yano, W., Kubota, T., Yamauchi, T., Itoh, S., Kumagai, H., Kozono, H., Takamoto, I., Okamoto, S., Shiuchi, T., et al. (2007) · Cell Metabolism

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 844

Continuous glucose monitoring and metrics for clinical trials: an international consensus statement

Battelino, T., Alexander, C. M., Amiel, S. A., Arreaza-Rubin, G., Beck, R. W., Bergenstal, R. M., Buckingham, B. A., Carroll, J., Ceriello, A., Chow, E., et al. (2023) · The Lancet Diabetes & Endocrinology

Diabetes Management and ResearchDiabetes Treatment and Management

Cited by 831

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity

Okada-Iwabu, M., Yamauchi, T., Iwabu, M., Honma, T., Hamagami, K.-I., Matsuda, K., Yamaguchi, M., Tanabe, H., Kimura-Someya, T., Shirouzu, M., et al. (2013) · Nature

Adipokines, Inflammation, and Metabolic DiseasesPeroxisome Proliferator-Activated Receptors

Cited by 757

Suppressor of Cytokine Signaling 1 (SOCS-1) and SOCS-3 Cause Insulin Resistance through Inhibition of Tyrosine Phosphorylation of Insulin Receptor Substrate Proteins by Discrete Mechanisms

Ueki, K., Kondo, T., & Kahn, C. R. (2004) · Molecular and Cellular Biology

Adipokines, Inflammation, and Metabolic DiseasesCytokine Signaling Pathways and Interactions

Cited by 686

Report of the Committee on the classification and diagnostic criteria of diabetes mellitus: The Committee of the Japan Diabetes Society on the diagnostic criteria of diabetes mellitus

Seino, Y., Nanjo, K., Tajima, N., Kadowaki, T., Kashiwagi, A., Araki, E., Ito, C., Inagaki, N., Iwamoto, Y., Kasuga, M., et al. (2010) · Diabetology International

Diabetes Management and ResearchDiabetes and associated disorders

Cited by 614

Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity

Tsuchida, A., Yamauchi, T., Ito, Y., Hada, Y., Maki, T., Takekawa, S., Kamon, J., Kobayashi, M., Suzuki, R., Hara, K., et al. (2004) · Journal of Biological Chemistry

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 550

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

Kubota, T., Kubota, N., Kumagai, H., Yamaguchi, S., Kozono, H., Takahashi, T., Inoue, M., Itoh, S., Takamoto, I., Sasako, T., et al. (2011) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 435

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3–kinase

Terauchi, Y., Tsuji, Y., Satoh, S., Minoura, H., Murakami, K., Okuno, A., Inukai, K., Asano, T., Kaburagi, Y., Ueki, K., et al. (1999) · Nature Genetics

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 399

Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial

Ueki, K., Sasako, T., Okazaki, Y., Kato, M., Okahata, S., Katsuyama, H., Haraguchi, M., Morita, A., Ohashi, K., Hara, K., et al. (2017) · The Lancet Diabetes & Endocrinology

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 313

Adiponectin Enhances Insulin Sensitivity by Increasing Hepatic IRS-2 Expression via a Macrophage-Derived IL-6-Dependent Pathway

Awazawa, M., Ueki, K., Inabe, K., Yamauchi, T., Kubota, N., Kaneko, K., Kobayashi, M., Iwane, A., Sasako, T., Okazaki, Y., et al. (2011) · Cell Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 277

Dynamic Functional Relay between Insulin Receptor Substrate 1 and 2 in Hepatic Insulin Signaling during Fasting and Feeding

Kubota, N., Kubota, T., Itoh, S., Kumagai, H., Kozono, H., Takamoto, I., Mineyama, T., Ogata, H., Tokuyama, K., Ohsugi, M., et al. (2008) · Cell Metabolism

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 244

Insulin receptor substrate 2 plays a crucial role in β cells and the hypothalamus

Kubota, N., Terauchi, Y., Tobe, K., Yano, W., Suzuki, R., Ueki, K., Takamoto, I., Satoh, H., Maki, T., Kubota, T., et al. (2004) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 239

Site and mechanism of leptin action in a rodent form of congenital lipodystrophy

Asilmaz, E., Cohen, P., Miyazaki, M., Dobrzyn, P., Ueki, K., Fayzikhodjaeva, G., Soukas, A. A., Kahn, C. R., Ntambi, J. M., Socci, N. D., et al. (2004) · Journal of Clinical Investigation

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 210

Metagenomic Identification of Microbial Signatures Predicting Pancreatic Cancer From a Multinational Study

Nagata, N., Nishijima, S., Kojima, Y., Hisada, Y., Imbe, K., Miyoshi-Akiyama, T., Suda, W., Kimura, M., Aoki, R., Sekine, K., et al. (2022) · Gastroenterology

Gut microbiota and healthPancreatic and Hepatic Oncology Research

Cited by 209

A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese diabetic mice

Fujimoto, M., Shimizu, N., Kunii, K., Martyn, J. A. J., Ueki, K., & Kaneki, M. (2005) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesNitric Oxide and Endothelin Effects

Cited by 209

Reduced expression of the murine p85α subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

Mauvais-Jarvis, F., Ueki, K., Fruman, D. A., Hirshman, M. F., Sakamoto, K., Goodyear, L. J., Iannacone, M., Accili, D., Cantley, L. C., & Kahn, C. R. (2002) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 207

Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in βIRKO mice

Otani, K., Kulkarni, R. N., Baldwin, A. C., Krutzfeldt, J., Ueki, K., Stoffel, M., Kahn, C. R., & Polonsky, K. S. (2004) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 185

Population-level Metagenomics Uncovers Distinct Effects of Multiple Medications on the Human Gut Microbiome

Nagata, N., Nishijima, S., Miyoshi-Akiyama, T., Kojima, Y., Kimura, M., Aoki, R., Ohsugi, M., Ueki, K., Miki, K., Iwata, E., et al. (2022) · Gastroenterology

Gut microbiota and healthAntibiotic Resistance in Bacteria

Cited by 178

Essential Role of Insulin Receptor Substrate-2 in Insulin Stimulation of Glut4 Translocation and Glucose Uptake in Brown Adipocytes

Fasshauer, M., Klein, J., Ueki, K., Kriauciunas, K. M., Benito, M., White, M. F., & Kahn, C. R. (2000) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 176