Urlaub, Henning

Molecular anatomy of a trafficking organelle

Takamori, S., Holt, M., Stenius, K., Lemke, E. A., Grønborg, M., Riedel, D., Urlaub, H., Schenck, S., Brügger, B., Ringler, P., et al. (2006) · Cell

Cellular transport and secretionExtracellular vesicles in disease

Cited by 2,373

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

Wilhelm, B. G., Mandad, S., Truckenbrodt, S., Kröhnert, K., Schäfer, C., Rammner, B., Koo, S. J., Claßen, G. A., Krauss, M., Haucke, V., et al. (2014) · Science

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 770

Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

Kadavath, H., Hofele, R. V., Biernat, J., Kumar, S., Tepper, K., Urlaub, H., Mandelkow, E., & Zweckstetter, M. (2015) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsMicrotubule and mitosis dynamics

Cited by 524

Structure of activated transcription complex Pol II–DSIF–PAF–SPT6

Vos, S. M., Farnung, L., Boehning, M., Wigge, C., Linden, A., Urlaub, H., & Cramer, P. (2018) · Nature

Genomics and Chromatin DynamicsRNA Research and Splicing

Cited by 432

CASK Functions as a Mg2+-independent neurexin kinase

Mukherjee, K., Sharma, M., Urlaub, H., Bourenkov, G. P., Jahn, R., Südhof, T. C., & Wahl, M. C. (2008) · Cell

Protein Kinase Regulation and GTPase SignalingNeuroscience and Neuropharmacology Research

Cited by 271

BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions

Fard, M. K., van der Meer, F., Sánchez, P., Cantuti-Castelvetri, L., Mandad, S., Jäkel, S., Fornasiero, E. F., Schmitt, S., Ehrlich, M., Starost, L., et al. (2017) · Science Translational Medicine

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 247

Structure and conformational dynamics of the human spliceosomal Bact complex

Haselbach, D., Komarov, I., Agafonov, D. E., Hartmuth, K., Graf, B., Dybkov, O., Urlaub, H., Kastner, B., Lührmann, R., & Stark, H. (2018) · Cell

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 218

A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila

Owald, D., Fouquet, W., Schmidt, M., Wichmann, C., Mertel, S., Depner, H., Christiansen, F., Zube, C., Quentin, C., Körner, J., et al. (2010) · Journal of Cell Biology

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 191

Structural basis of TFIIH activation for nucleotide excision repair

Kokic, G., Chernev, A., Tegunov, D., Dienemann, C., Urlaub, H., & Cramer, P. (2019) · Nature Communications

DNA Repair MechanismsEnzyme Structure and Function

Cited by 163

Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation

Vos, S. M., Farnung, L., Linden, A., Urlaub, H., & Cramer, P. (2020) · Nature Structural & Molecular Biology

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 160

Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting

Biesemann, C., Grønborg, M., Luquet, E., Wichert, S. P., Bernard, V., Bungers, S. R., Cooper, B., Varoqueaux, F., Li, L., Byrne, J. A., et al. (2014) · The EMBO Journal

Neuroscience and Neuropharmacology ResearchAdvanced Proteomics Techniques and Applications

Cited by 156

Late motor decline after accomplished remyelination: Impact for progressive multiple sclerosis

Manrique‐Hoyos, N., Jürgens, T., Grønborg, M., Kreutzfeldt, M., Schedensack, M., Kuhlmann, T., Schrick, C., Brück, W., Urlaub, H., Simons, M., et al. (2012) · Annals of Neurology

Multiple Sclerosis Research StudiesPeripheral Neuropathies and Disorders

Cited by 107

Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex

Oroz, J., Chang, B. J., Wysoczanski, P., Lee, C.-T., Pérez-Lara, Á., Chakraborty, P., Hofele, R. V., Baker, J. D., Blair, L. J., Biernat, J., et al. (2018) · Nature Communications

Heat shock proteins researchAlzheimer's disease research and treatments

Cited by 100

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes

De, I., Bessonov, S., Hofele, R., dos Santos, K., Will, C. L., Urlaub, H., Lührmann, R., & Pena, V. (2015) · Nature Structural & Molecular Biology

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 89

Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3

Upmanyu, N., Jin, J., Emde, H. V. D., Ganzella, M., Bösche, L., Malviya, V. N., Zhuleku, E., Politi, A. Z., Ninov, M., Silbern, I., et al. (2022) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 69

A viral ADP-ribosyltransferase attaches RNA chains to host proteins

Wolfram-Schauerte, M., Pozhydaieva, N., Grawenhoff, J., Welp, L. M., Silbern, I., Wulf, A., Billau, F. A., Glatter, T., Urlaub, H., Jäschke, A., et al. (2023) · Nature

RNA and protein synthesis mechanismsBacteriophages and microbial interactions

Cited by 53

Metamorphic proteins at the basis of human autophagy initiation and lipid transfer

Nguyen, A., Lugarini, F., David, C., Hosnani, P., Knotkova, B., Patel, A., Parfentev, I., Friedrich, A., Urlaub, H., Meinecke, M., et al. (2022) · Molecular Cell

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 47

Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8

Helmke, C., Raab, M., Rödel, F., Matthess, Y., Oellerich, T., Mandal, R., Sanhaji, M., Urlaub, H., Rödel, C., Becker, S., et al. (2016) · Cell Research

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 44

Uncovering the temporal dynamics and regulatory networks of thermal stress response in a hyperthermophile using transcriptomics and proteomics

Grünberger, F., Schmid, G., El Ahmad, Z., Fenk, M., Vogl, K., Reichelt, R., Hausner, W., Urlaub, H., Lenz, C., & Grohmann, D. (2023) · mBio

Bacterial Genetics and BiotechnologyHeat shock proteins research

Cited by 24

Uncovering the temporal dynamics and regulatory networks of thermal stress response in a hyperthermophile using transcriptomics and proteomics

Grünberger, F., Schmid, G., Ahmad, Z. E., Fenk, M., Vogl, K., Reichelt, R., Hausner, W., Urlaub, H., Lenz, C., & Grohmann, D. (2023) · mBio

Bacterial Genetics and BiotechnologyHeat shock proteins research

Cited by 24

Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1

Düring, J., Wolter, M., Toplak, J. J., Torres, C., Dybkov, O., Fokkens, T. J., Bohnsack, K. E., Urlaub, H., Steinchen, W., Dienemann, C., et al. (2024) · Nature Structural & Molecular Biology

Ubiquitin and proteasome pathwaysEnzyme Structure and Function

Cited by 20

Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II

Rengachari, S., Schilbach, S., Kaliyappan, T., Gouge, J., Zumer, K., Schwarz, J., Urlaub, H., Dienemann, C., Vannini, A., & Cramer, P. (2022) · Nature Structural & Molecular Biology

Genomics and Chromatin DynamicsRNA Research and Splicing

Cited by 19

Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA

Keil, P., Wulf, A., Kachariya, N., Reuscher, S., Hühn, K., Silbern, I., Altmüller, J., Keller, M., Stehle, R., Zarnack, K., et al. (2023) · Nucleic Acids Research

RNA Research and SplicingGenomics and Chromatin Dynamics

Cited by 17

Fasting‐sensitive SUMO‐switch on Prox1 controls hepatic cholesterol metabolism

Alfaro, A. J., Dittner, C., Becker, J., Loft, A., Mhamane, A., Maida, A., Georgiadi, A., Tsokanos, F., Klepac, K., Molocea, C., et al. (2023) · The EMBO Reports

Cholesterol and Lipid MetabolismLiver Disease Diagnosis and Treatment

Cited by 14