Long-range enhancer–promoter contacts in gene expression control

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Capturing Chromosome Conformation

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Formation of chromosomal domains by loop extrusion

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Mediator and cohesin connect gene expression and chromatin architecture

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Cohesin Loss Eliminates All Loop Domains

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Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

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Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

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A Phase Separation Model for Transcriptional Control

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Stochastic mRNA Synthesis in Mammalian Cells

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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

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An oestrogen-receptor-α-bound human chromatin interactome

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Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization

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Chromatin architecture reorganization during stem cell differentiation

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ChIP-seq accurately predicts tissue-specific activity of enhancers

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Single-cell Hi-C reveals cell-to-cell variability in chromosome structure

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The long-range interaction landscape of gene promoters

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Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

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Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C)

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A map of the cis-regulatory sequences in the mouse genome

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Multiscale 3D Genome Rewiring during Mouse Neural Development

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Insulator dysfunction and oncogene activation in IDH mutant gliomas

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Hi–C: A comprehensive technique to capture the conformation of genomes

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Editing DNA Methylation in the Mammalian Genome

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Obesity-associated variants within FTO form long-range functional connections with IRX3

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A high-resolution map of the three-dimensional chromatin interactome in human cells

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Two independent modes of chromatin organization revealed by cohesin removal

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Cohesin mediates transcriptional insulation by CCCTC-binding factor

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Architectural protein subclasses shape 3D organization of genomes during lineage commitment

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Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elementsPreprint

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Organization and function of the 3D genome

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Organizational principles of 3D genome architecture

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A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly

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HiChIP: efficient and sensitive analysis of protein-directed genome architecture

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Genome-Wide Quantitative Enhancer Activity Maps Identified by STARR-seq

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VISTA Enhancer Browser—a database of tissue-specific human enhancers

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Active genes dynamically colocalize to shared sites of ongoing transcription

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Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

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Activation of proto-oncogenes by disruption of chromosome neighborhoods

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Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

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YY1 Is a Structural Regulator of Enhancer-Promoter Loops

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Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

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CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription

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Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells

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The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome

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Imaging dynamic and selective low-complexity domain interactions that control gene transcription

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CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

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Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions

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Ever-Changing Landscapes: Transcriptional Enhancers in Development and Evolution

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Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms

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BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

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Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes

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Super-resolution imaging reveals distinct chromatin folding for different epigenetic states

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Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins

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Activating RNAs associate with Mediator to enhance chromatin architecture and transcription

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Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis

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Cell-cycle dynamics of chromosomal organization at single-cell resolution

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The cohesin release factor WAPL restricts chromatin loop extension

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Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor

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Genome Architecture: Domain Organization of Interphase Chromosomes

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Enhancer Control of Transcriptional Bursting

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Complex multi-enhancer contacts captured by genome architecture mapping

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Transcriptional Pulsing of a Developmental Gene

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Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells

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A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia

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Formation of new chromatin domains determines pathogenicity of genomic duplications

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Long-range chromatin regulatory interactions in vivo

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Functional annotation of native enhancers with a Cas9–histone demethylase fusion

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An Erythroid Enhancer of <i>BCL11A</i> Subject to Genetic Variation Determines Fetal Hemoglobin Level

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Systematic mapping of functional enhancer–promoter connections with CRISPR interference

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