Hannun, Yusuf A.

Programmed Cell Death Induced by Ceramide

Obeid, L. M., Linardic, C. M., Karolak, L. A., & Hannun, Y. A. (1993) · Science

Sphingolipid Metabolism and SignalingCell death mechanisms and regulation

Cited by 1,794

Bioactive sphingolipids: metabolism and function

Bartke, N., & Hannun, Y. A. (2009) · Journal of Lipid Research

Sphingolipid Metabolism and SignalingLysosomal Storage Disorders Research

Cited by 683

Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome

Yang, G., Badeanlou, L., Bielawski, J., Roberts, A. J., Hannun, Y. A., & Samad, F. (2009) · American Journal of Physiology-Endocrinology and Metabolism

Sphingolipid Metabolism and SignalingAdipokines, Inflammation, and Metabolic Diseases

Cited by 295

Ceramide is metabolized to acylceramide and stored in lipid droplets

Senkal, C. E., Salama, M. F., Snider, A. J., Allopenna, J. J., Rana, N. A., Koller, A., Hannun, Y. A., & Obeid, L. M. (2017) · Cell Metabolism

Sphingolipid Metabolism and SignalingLipid metabolism and biosynthesis

Cited by 237

Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C

Khan, W. A., Blobe, G. C., & Hannun, Y. A. (1995) · Cellular Signalling

Protein Kinase Regulation and GTPase SignalingSphingolipid Metabolism and Signaling

Cited by 225

Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice

Alsamman, S., Christenson, S. A., Yu, A., Ayad, N. M. E., Mooring, M. S., Segal, J. M., Hu, J. K.-H., Schaub, J. R., Ho, S. S., Rao, V., et al. (2020) · Science Translational Medicine

Liver physiology and pathologySphingolipid Metabolism and Signaling

Cited by 122

Necessary Role for the Lag1p Motif in (Dihydro)ceramide Synthase Activity

Spassieva, S., Seo, J.-G., Jiang, J. C., Bielawski, J., Alvarez-Vasquez, F., Jazwinski, S. M., Hannun, Y. A., & Obeid, L. M. (2006) · Journal of Biological Chemistry

Sphingolipid Metabolism and SignalingLipid metabolism and biosynthesis

Cited by 121

Golgi maturation‐dependent glycoenzyme recycling controls glycosphingolipid biosynthesis and cell growth via GOLPH3

Rizzo, R., Russo, D., Kurokawa, K., Sahu, P., Lombardi, B., Supino, D., Zhukovsky, M. A., Vocat, A., Pothukuchi, P., Kunnathully, V., et al. (2021) · The EMBO Journal

Sphingolipid Metabolism and SignalingCellular transport and secretion

Cited by 101

De novo N-palmitoylsphingosine synthesis is the major biochemical mechanism of ceramide accumulation following p53 up-regulation

Panjarian, S., Kozhaya, L., Arayssi, S., Yehia, M., Bielawski, J., Bielawska, A., Usta, J., Hannun, Y. A., Obeid, L. M., & Dbaibo, G. S. (2008) · Prostaglandins & Other Lipid Mediators

Sphingolipid Metabolism and SignalingCancer, Lipids, and Metabolism

Cited by 69

Protein Kinase C as a Therapeutic Target in Non-Small Cell Lung Cancer

Sadeghi, M. M., Salama, M. F., & Hannun, Y. A. (2021) · International Journal of Molecular Sciences

Lung Cancer Treatments and MutationsProtein Kinase Regulation and GTPase Signaling

Cited by 31