Ganapathy, Vadivel

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

Singh, N., Gurav, A., Sivaprakasam, S., Brady, E., Padia, R., Shi, H., Thangaraju, M., Prasad, P. D., Manicassamy, S., Munn, D. H., et al. (2014) · Immunity

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 2,368

GPR109A Is a G-protein–Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

Thangaraju, M., Cresci, G. A., Liu, K., Ananth, S., Gnanaprakasam, J. P., Browning, D. D., Mellinger, J. D., Smith, S. B., Digby, G. J., Lambert, N. A., et al. (2009) · Cancer Research

Gut microbiota and healthReceptor Mechanisms and Signaling

Cited by 789

Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases

Singh, N., Thangaraju, M., Prasad, P. D., Martin, P. M., Lambert, N. A., Boettger, T., Offermanns, S., & Ganapathy, V. (2010) · Journal of Biological Chemistry

Gut microbiota and healthImmunotherapy and Immune Responses

Cited by 293

Transporters and receptors for short-chain fatty acids as the molecular link between colonic bacteria and the host

Ganapathy, V., Thangaraju, M., Prasad, P. D., Martin, P. M., & Singh, N. (2013) · Current Opinion in Pharmacology

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 290

β-Lactam Antibiotics as Substrates for OCTN2, an Organic Cation/Carnitine Transporter

Ganapathy, M. E., Huang, W., Rajan, D. P., Carter, A. L., Sugawara, M., Iseki, K., Leibach, F. H., & Ganapathy, V. (2000) · Journal of Biological Chemistry

Drug Transport and Resistance MechanismsAntibiotics Pharmacokinetics and Efficacy

Cited by 175

Human Placental Sodium-Dependent Vitamin C Transporter (SVCT2): Molecular Cloning and Transport Function

Rajan, D. P., Huang, W., Dutta, B., Devoe, L. D., Leibach, F. H., Ganapathy, V., & Prasad, P. D. (1999) · Biochemical and Biophysical Research Communications

Vitamin C and Antioxidants ResearchAmino Acid Enzymes and Metabolism

Cited by 162

Taurine uptake across the human intestinal brush‐border membrane is via two transporters: H + ‐coupled PAT1 (SLC36A1) and Na + ‐ and Cl − ‐dependent TauT (SLC6A6)

Anderson, C. M. H., Howard, A., Walters, J. R. F., Ganapathy, V., & Thwaites, D. T. (2009) · The Journal of Physiology

Aldose Reductase and TaurineAmino Acid Enzymes and Metabolism

Cited by 141

Hypoxia reduces expression and function of system A amino acid transporters in cultured term human trophoblasts

Nelson, D. M., Smith, S. D., Furesz, T. C., Sadovsky, Y., Ganapathy, V., Parvin, C. A., & Smith, C. H. (2003) · American Journal of Physiology-Cell Physiology

Pregnancy and preeclampsia studiesAmino Acid Enzymes and Metabolism

Cited by 112

Transport of d-Serine via the Amino Acid Transporter ATB0,+ Expressed in the Colon

Hatanaka, T., Huang, W., Nakanishi, T., Bridges, C. C., Smith, S. B., Prasad, P. D., Ganapathy, M. E., & Ganapathy, V. (2002) · Biochemical and Biophysical Research Communications

Amino Acid Enzymes and MetabolismDrug Transport and Resistance Mechanisms

Cited by 99

Carnitine transport and its inhibition by sulfonylureas in human kidney proximal tubular epithelial cells

Huang, W., Shaikh, S. N., Ganapathy, M. E., Hopfer, U., Leibach, F. H., Carter, A. L., & Ganapathy, V. (1999) · Biochemical Pharmacology

Amino Acid Enzymes and MetabolismMetabolism and Genetic Disorders

Cited by 22