Riley, James L.

CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms

Parry, R. V., Chemnitz, J. M., Frauwirth, K. A., Lanfranco, A. R., Braunstein, I., Kobayashi, S. V., Linsley, P. S., Thompson, C. B., & Riley, J. L. (2005) · Molecular and Cellular Biology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 1,931

The CD28 Signaling Pathway Regulates Glucose Metabolism

Frauwirth, K. A., Riley, J. L., Harris, M. H., Parry, R. V., Rathmell, J. C., Plas, D. R., Elstrom, R. L., June, C. H., & Thompson, C. B. (2002) · Immunity

T-cell and B-cell ImmunologyMetabolism, Diabetes, and Cancer

Cited by 1,475

SHP-1 and SHP-2 Associate with Immunoreceptor Tyrosine-Based Switch Motif of Programmed Death 1 upon Primary Human T Cell Stimulation, but Only Receptor Ligation Prevents T Cell Activation

Chemnitz, J. M., Parry, R. V., Nichols, K. E., June, C. H., & Riley, J. L. (2004) · The Journal of Immunology

Protein Tyrosine PhosphatasesT-cell and B-cell Immunology

Cited by 1,246

Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

Milone, M. C., Fish, J. D., Carpenito, C., Carroll, R. G., Binder, G. K., Teachey, D., Samanta, M., Lakhal, M., Gloss, B., Danet-Desnoyers, G., et al. (2009) · Molecular Therapy

CAR-T cell therapy researchImmunotherapy and Immune Responses

Cited by 1,197

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

Perez, E. E., Wang, J., Miller, J. C., Jouvenot, Y., Kim, K. A., Liu, O., Wang, N., Lee, G., Bartsevich, V. V., Lee, Y.-L., et al. (2008) · Nature Biotechnology

CRISPR and Genetic EngineeringHIV Research and Treatment

Cited by 999

PD-1 signaling in primary T cells

Riley, J. L. (2009) · Immunological Reviews

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 778

Engineering Artificial Antigen-presenting Cells to Express a Diverse Array of Co-stimulatory Molecules

Suhoski, M. M., Golovina, T. N., Aqui, N. A., Tai, V. C., Varela-Rohena, A., Milone, M. C., Carroll, R. G., Riley, J. L., & June, C. H. (2007) · Molecular Therapy

Immunotherapy and Immune ResponsesVirus-based gene therapy research

Cited by 266

Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases

Wilen, C. B., Wang, J., Tilton, J. C., Miller, J. C., Kim, K. A., Rebar, E. J., Sherrill-Mix, S. A., Patro, S. C., Secreto, A. J., Jordan, A. P. O., et al. (2011) · PLoS Pathogens

HIV Research and TreatmentCRISPR and Genetic Engineering

Cited by 142

Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5

Maier, D. A., Brennan, A. L., Jiang, S., Binder-Scholl, G. K., Lee, G., Plesa, G., Zheng, Z., Cotte, J., Carpenito, C., Wood, T., et al. (2013) · Human Gene Therapy

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 126

RETRACTED: Robust expansion of HIV CAR T cells following antigen boosting in ART-suppressed nonhuman primates

Rust, B. J., Kean, L. S., Colonna, L., Brandenstein, K. E., Poole, N. H., Obenza, W., Enstrom, M. R., Maldini, C. R., Ellis, G. I., Fennessey, C. M., et al. (2020) · Blood

HIV Research and TreatmentCAR-T cell therapy research

Cited by 58