Engineering Artificial Antigen-presenting Cells to Express a Diverse Array of Co-stimulatory Molecules

Tolerogenic Dendritic Cells

Steinman, R. M., Hawiger, D., & Nussenzweig, M. C. (2003) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141040 · Cited by 3,124 · see citing works

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

Dudley, M. E., Wunderlich, J. R., Robbins, P. F., Yang, J. C., Hwu, P., Schwartzentruber, D. J., Topalian, S. L., Sherry, R., Restifo, N. P., Hubicki, A. M., et al. (2002) · Science · doi:10.1126/science.1076514 · Cited by 2,823 · see citing works

IgG Fc Receptors

Ravetch, J. V., & Bolland, S. M. (2001) · Annual Review of Immunology · doi:10.1146/annurev.immunol.19.1.275 · Cited by 1,653 · see citing works

Antigen-Specific Inhibition of Effector T Cell Function in Humans after Injection of Immature Dendritic Cells

Dhodapkar, M. V., Steinman, R. M., Krasovsky, J., Münz, C., & Bhardwaj, N. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.193.2.233 · Cited by 1,359 · see citing works

Dendritic cells as therapeutic vaccines against cancer

Banchereau, J., & Palucka, A. K. (2005) · Nature reviews. Immunology · doi:10.1038/nri1592 · Cited by 1,195 · see citing works

The Duration of Antigenic Stimulation Determines the Fate of Naive and Effector T Cells

Iezzi, G., Karjalainen, K., & Lanzavecchia, A. (1998) · Immunity · doi:10.1016/s1074-7613(00)80461-6 · Cited by 909 · see citing works

Clinical significance of defective dendritic cell differentiation in cancer.

Almand, B., Resser, J. R., Lindman, B. R., Nadaf, S., Clark, J. I., Kwon, E. D., Carbone, D. P., & Gabrilovich, D. I. (2000) · PubMed · Cited by 699 · see citing works

T-Cell Proliferation Involving the CD28 Pathway Is Associated witH Cyclosporine-Resistant Interleukin 2 Gene Expression

June, C. H., Ledbetter, J. A., Gillespie, M., Lindsten, T., & Thompson, C. B. (1987) · Molecular and Cellular Biology · doi:10.1128/mcb.7.12.4472-4481.1987 · Cited by 565 · see citing works

Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells

Dhodapkar, M. V., Steinman, R. M., Sapp, M., Desai, H., Fossella, C., Krasovsky, J., Donahoe, S. M., Dunbar, P. R., Cerundolo, V., Nixon, D. F., et al. (1999) · Journal of Clinical Investigation · doi:10.1172/jci6909 · Cited by 467 · see citing works

Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB

Maus, M. V., Thomas, A., Leonard, D. G. B., Allman, D., Addya, K., Schlienger, K., Riley, J. L., & June, C. H. (2002) · Nature Biotechnology · doi:10.1038/nbt0202-143 · Cited by 455 · see citing works

Shortened telomeres in clonally expanded CD28-CD8+ T cells imply a replicative history that is distinct from their CD28+CD8+ counterparts

Monteiro, J., Batliwalla, F., Ostrer, H., & Gregersen, P. K. (1996) · The Journal of Immunology · doi:10.4049/jimmunol.156.10.3587 · Cited by 376 · see citing works

Effects of CD28 costimulation on long-term proliferation of CD4+ T cells in the absence of exogenous feeder cells

Levine, B. L., Bernstein, W. B., Connors, M., Craighead, N., Lindsten, T., Thompson, C. B., & June, C. H. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.159.12.5921 · Cited by 340 · see citing works

The role of CD8⁺ T‐cell replicative senescence in human aging

Effros, R. B., Dagarag, M., Spaulding, C., & Man, J. (2005) · Immunological Reviews · doi:10.1111/j.0105-2896.2005.00259.x · Cited by 336 · see citing works

Telomere Length of Transferred Lymphocytes Correlates with In Vivo Persistence and Tumor Regression in Melanoma Patients Receiving Cell Transfer Therapy

Zhou, J., Shen, X., Huang, J., Hodes, R. J., Rosenberg, S. A., & Robbins, P. F. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.10.7046 · Cited by 336 · see citing works

Dendritic Cells as Sensors of Infection

Sousa, C. R. E. (2001) · Immunity · doi:10.1016/s1074-7613(01)00136-4 · Cited by 320 · see citing works

Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig–coated artificial antigen-presenting cells

Oelke, M., Maus, M. V., Didiano, D., June, C. H., Mackensen, A., & Schneck, J. P. (2003) · Nature Medicine · doi:10.1038/nm869 · Cited by 306 · see citing works

Dendritic cells: On the move from bench to bedside

Nestle, F. O., Banchereau, J., & Hart, D. N. J. (2001) · Nature Medicine · doi:10.1038/89863 · Cited by 288 · see citing works

Anergy and apoptosis in CD8+ T cells from HIV-infected persons.

Lewis, D. E., Tang, D. S. N., Adu-Oppong, A., Schober, W. D., & Rodgers, J. R. (1994) · The Journal of Immunology · doi:10.4049/jimmunol.153.1.412 · Cited by 234 · see citing works

Induction of human cytotoxic T lymphocytes by artificial antigen-presenting cells

Latouche, J., & Sadelain, M. (2000) · Nature Biotechnology · doi:10.1038/74455 · Cited by 177 · see citing works

Production and concentration of pseudotyped HIV-1-based gene transfer vectors

Reiser, J. (2000) · Gene Therapy · doi:10.1038/sj.gt.3301188 · Cited by 176 · see citing works

CD28 and Inducible Costimulatory Protein Src Homology 2 Binding Domains Show Distinct Regulation of Phosphatidylinositol 3-Kinase, Bcl-xL, and IL-2 Expression in Primary Human CD4 T Lymphocytes

Parry, R. V., Rumbley, C. A., Vandenberghe, L. H., June, C. H., & Riley, J. L. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.1.166 · Cited by 169 · see citing works

Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity

Hirano, N., Butler, M. O., Xia, Z., Ansén, S., von Bergwelt‐Baildon, M. S., Neuberg, D. S., Freeman, G. J., & Nadler, L. M. (2005) · Blood · doi:10.1182/blood-2005-05-2073 · Cited by 168 · see citing works

Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed leukocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes.

Inaba, K., & Steinman, R. M. (1987) · The Journal of Experimental Medicine · doi:10.1084/jem.165.5.1403 · Cited by 128 · see citing works

The use of HLA-A*0201-transfected K562 as standard antigen-presenting cells for CD8+ T lymphocytes in IFN-γ ELISPOT assays

Britten, C. M., Meyer, R. G., Kreer, T., Drexler, I., Wölfel, T., & Herr, W. (2002) · Journal of Immunological Methods · doi:10.1016/s0022-1759(01)00499-9 · Cited by 125 · see citing works

A Cell-Based Artificial Antigen-Presenting Cell Coated with Anti-CD3 and CD28 Antibodies Enables Rapid Expansion and Long-Term Growth of CD4 T Lymphocytes

Thomas, A., Maus, M. V., Shalaby, W. S. W., June, C. H., & Riley, J. L. (2002) · Clinical Immunology · doi:10.1006/clim.2002.5277 · Cited by 96 · see citing works

Response Differences between Human CD4+ and CD8+ T-Cells during CD28 Costimulation: Implications for Immune Cell-Based Therapies and Studies Related to the Expansion of Double-Positive T-Cells during Aging

Laux, I., Khoshnan, A., Tindell, C., Bae, D. J., Zhu, X., June, C. H., Effros, R. B., & Nel, A. E. (2000) · Clinical Immunology · doi:10.1006/clim.2000.4902 · Cited by 89 · see citing works

Characterization of an artificial antigen-presenting cell to propagate cytolytic CD19-specific T cells

Numbenjapon, T., Serrano, L. M., Singh, H., Kowolik, C. M., Olivares, S., Gonzalez, N., Chang, W. C., Forman, S. J., Jensen, M. C., & Cooper, L. J. N. (2006) · Leukemia · doi:10.1038/sj.leu.2404329 · Cited by 29 · see citing works

In vitro expansion of Ag-specific T cells by HLA-A*0201-transfected K562 cells for immune monitoring

Yuan, J. D., Gallardo, H. F., Rasalan, T. S., Ranganathan, R., Wang, J., Zhang, Y., Panageas, K. S., Stan, R., Young, J. W., Houghton, A. N., et al. (2006) · Cytotherapy · doi:10.1080/14653240600868262 · Cited by 16 · see citing works

Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

Milone, M. C., Fish, J. D., Carpenito, C., Carroll, R. G., Binder, G. K., Teachey, D., Samanta, M., Lakhal, M., Gloss, B., Danet-Desnoyers, G., et al. (2009) · Molecular Therapy · doi:10.1038/mt.2009.83 · Cited by 1,197 · see citing works

Clinical use of lentiviral vectors

Milone, M. C., & O’Doherty, U. (2018) · Leukemia · doi:10.1038/s41375-018-0106-0 · Cited by 930 · see citing works

PD-1 signaling in primary T cells

Riley, J. L. (2009) · Immunological Reviews · doi:10.1111/j.1600-065x.2009.00767.x · Cited by 778 · see citing works

Global Manufacturing of CAR T Cell Therapy

Levine, B. L., Miskin, J., Wonnacott, K., & Keir, C. (2017) · Molecular Therapy - Methods & Clinical Development · doi:10.1016/j.omtm.2016.12.006 · Cited by 765 · see citing works

Membrane-Bound IL-21 Promotes Sustained Ex Vivo Proliferation of Human Natural Killer Cells

Denman, C. J., Senyukov, V., Somanchi, S. S., Phatarpekar, P. V., Kopp, L. M., Johnson, J. L., Singh, H., Hurton, L. V., Maiti, S. N., Huls, M. H., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030264 · Cited by 683 · see citing works

Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy

Yang, R., Sun, L., Li, C.-F., Wang, Y.-H., Yao, J., Li, H., Yan, M., Chang, W., Hsu, J.-M., Cha, J., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-21099-2 · Cited by 637 · see citing works

Clinical manufacturing of CAR T cells: foundation of a promising therapy

Wang, X., & Rivière, I. (2016) · Molecular Therapy - Oncolytics · doi:10.1038/mto.2016.15 · Cited by 637 · see citing works

Expression of a Functional CCR2 Receptor Enhances Tumor Localization and Tumor Eradication by Retargeted Human T cells Expressing a Mesothelin-Specific Chimeric Antibody Receptor

Moon, E. K., Carpenito, C., Sun, J., Wang, L. S., Kapoor, V., Predina, J. D., Powell, D. J., Riley, J. L., June, C. H., & Albelda, S. Μ. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-0351 · Cited by 537 · see citing works

Multiple Injections of Electroporated Autologous T Cells Expressing a Chimeric Antigen Receptor Mediate Regression of Human Disseminated Tumor

Zhao, Y., Moon, E. K., Carpenito, C., Paulos, C. M., Liu, X., Brennan, A. L., Chew, A., Carroll, R. G., Scholler, J., Levine, B. L., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-2880 · Cited by 448 · see citing works

Umbilical cord blood–derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

Brunstein, C. G., Miller, J. S., McKenna, D. H., Hippen, K. L., DeFor, T. E., Sumstad, D., Curtsinger, J., Verneris, M. R., MacMillan, M. L., Levine, B. L., et al. (2015) · Blood · doi:10.1182/blood-2015-06-653667 · Cited by 416 · see citing works

Human T Regulatory Cell Therapy: Take a Billion or So and Call Me in the Morning

Riley, J. L., June, C. H., & Blazar, B. R. (2009) · Immunity · doi:10.1016/j.immuni.2009.04.006 · Cited by 412 · see citing works

Tuning Sensitivity of CAR to EGFR Density Limits Recognition of Normal Tissue While Maintaining Potent Antitumor Activity

Caruso, H. G., Hurton, L. V., Najjar, A. M., Rushworth, D., Ang, S., Olivares, S., Mi, T., Switzer, K. C., Singh, H., Huls, H. M., et al. (2015) · Cancer Research · doi:10.1158/0008-5472.can-15-0139 · Cited by 399 · see citing works

CD137 Accurately Identifies and Enriches for Naturally Occurring Tumor-Reactive T Cells in Tumor

Ye, Q., Song, D.-G., Poussin, M., Yamamoto, T. N., Best, A. J., Li, C., Coukos, G., & Powell, D. J. (2013) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-13-0945 · Cited by 324 · see citing works

Going viral: chimeric antigen receptor T‐cell therapy for hematological malignancies

Gill, S. I., & June, C. H. (2014) · Immunological Reviews · doi:10.1111/imr.12243 · Cited by 319 · see citing works

Strength of PD-1 signaling differentially affects T-cell effector functions

Wei, F., Zhong, S., Ma, Z., Kong, H., Medvec, A. R., Ahmed, R., Freeman, G. J., Krogsgaard, M., & Riley, J. L. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1305394110 · Cited by 306 · see citing works

Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor

Jena, B., Dotti, G., & Cooper, L. J. N. (2010) · Blood · doi:10.1182/blood-2010-01-043737 · Cited by 295 · see citing works

In Vivo Persistence, Tumor Localization, and Antitumor Activity of CAR-Engineered T Cells Is Enhanced by Costimulatory Signaling through CD137 (4-1BB)

Song, D.-G., Ye, Q., Carpenito, C., Poussin, M., Wang, L.-P., Ji, C., Figini, M., June, C. H., Coukos, G., & Powell, D. J. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-0422 · Cited by 287 · see citing works

Enhancing cell therapies from the outside in: Cell surface engineering using synthetic nanomaterials

Stephan, M. T., & Irvine, D. J. (2011) · Nano Today · doi:10.1016/j.nantod.2011.04.001 · Cited by 267 · see citing works

Adoptive Immunotherapy for Cancer or Viruses

Maus, M. V., Fraietta, J. A., Levine, B. L., Kalos, M. D., Zhao, Y., & June, C. H. (2014) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032713-120136 · Cited by 265 · see citing works

Clinical Grade Manufacturing of Human Alloantigen-Reactive Regulatory T Cells for Use in Transplantation

Putnam, A. L., Safinia, N., Medvec, A. R., Laszkowska, M., Wray, M., Mintz, M. A., Trotta, E., Szot, G. L., Liu, W., Lares, A., et al. (2013) · American Journal of Transplantation · doi:10.1111/ajt.12433 · Cited by 262 · see citing works

Principles of adoptive T cell cancer therapy

June, C. H. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31446 · Cited by 258 · see citing works

The Inducible Costimulator (ICOS) Is Critical for the Development of Human T H 17 Cells

Paulos, C. M., Carpenito, C., Plesa, G., Suhoski, M. M., Varela‐Rohena, A., Golovina, T. N., Carroll, R. G., Riley, J. L., & June, C. H. (2010) · Science Translational Medicine · doi:10.1126/scitranslmed.3000448 · Cited by 255 · see citing works

Adoptive T-Cell Therapy Using Autologous Tumor-Infiltrating Lymphocytes for Metastatic Melanoma

Wu, R. C. H., Forget, M., Chacon, J. A., Bernatchez, C., Haymaker, C., Chen, J. Q., Hwu, P., & Radvanyi, L. G. (2012) · The Cancer Journal · doi:10.1097/ppo.0b013e31824d4465 · Cited by 248 · see citing works

Redirecting Specificity of T-Cell Populations For CD19 Using the Sleeping Beauty System

Singh, H., Manuri, P. R., Olivares, S., Dara, N., Dawson, M. J., Huls, H. M., Hackett, P. B., Kohn, D. B., Shpall, E. J., Champlin, R. E., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-5600 · Cited by 246 · see citing works

Particle shape dependence of CD8+ T cell activation by artificial antigen presenting cells

Sunshine, J. C., Perica, K., Schneck, J. P., & Green, J. J. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.09.050 · Cited by 245 · see citing works

Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor

Varela‐Rohena, A., Molloy, P. E., Dunn, S. M., Li, Y., Suhoski, M. M., Carroll, R. G., Milicic, A., Mahon, T., Sutton, D. H., Laugel, B., et al. (2008) · Nature Medicine · doi:10.1038/nm.1779 · Cited by 243 · see citing works

Bioengineering T cells to target carbohydrate to treat opportunistic fungal infection

Kumaresan, P. R., Manuri, P. R., Albert, N. D., Maiti, S., Singh, H., Mi, T., Roszik, J., Rabinovich, B., Olivares, S., Krishnamurthy, J., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1312789111 · Cited by 237 · see citing works

Generation and Large-Scale Expansion of Human Inducible Regulatory T Cells That Suppress Graft-Versus-Host Disease

Hippen, K. L., Merkel, S. C., Schirm, D. K., Nelson, C. E., Tennis, N. C., Riley, J. L., June, C. H., Miller, J. S., Wagner, J. E., & Blazar, B. R. (2011) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2011.03558.x · Cited by 221 · see citing works

Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells

Barrett, D. M., Zhao, Y., Liu, X., Jiang, S., Carpenito, C., Kalos, M. D., Carroll, R. G., June, C. H., & Grupp, S. A. (2011) · Human Gene Therapy · doi:10.1089/hum.2011.070 · Cited by 220 · see citing works

Comparison of anti-CD3 and anti-CD28-coated beads with soluble anti-CD3 for expanding human T cells: Differing impact on CD8 T cell phenotype and responsiveness to restimulation

Li, Y., & Kurlander, R. J. (2010) · Journal of Translational Medicine · doi:10.1186/1479-5876-8-104 · Cited by 209 · see citing works

4-1BB Is Superior to CD28 Costimulation for Generating CD8+ Cytotoxic Lymphocytes for Adoptive Immunotherapy

Zhang, H., Snyder, K. M., Suhoski, M. M., Maus, M. V., Kapoor, V., June, C. H., & Mackall, C. L. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.7.4910 · Cited by 202 · see citing works

Reprogramming CD19-Specific T Cells with IL-21 Signaling Can Improve Adoptive Immunotherapy of B-Lineage Malignancies

Singh, H., Figliola, M. J., Dawson, M. J., Huls, H. M., Olivares, S., Switzer, K. C., Mi, T., Maiti, S. N., Kebriaei, P., Lee, D. A., et al. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-3843 · Cited by 199 · see citing works

Cutting Edge: Foxp3-Mediated Induction of Pim 2 Allows Human T Regulatory Cells to Preferentially Expand in Rapamycin

Basu, S., Golovina, T. N., Mikheeva, T., June, C. H., & Riley, J. L. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.9.5794 · Cited by 183 · see citing works

Regulatory T Cells as Immunotherapy

Singer, B. D., King, L. S., & D’Alessio, F. R. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00046 · Cited by 183 · see citing works

CAR–T cells and solid tumors: tuning T cells to challenge an inveterate foe

Gilham, D. E., Debets, R., Pulè, M. A., Hawkins, R. E., & Abken, H. (2012) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2012.04.009 · Cited by 179 · see citing works

CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo

Tian, G., Courtney, A. N., Jena, B., Heczey, A. A., Liu, D., Marinova, E., Guo, L., Xu, X. Y., Torikai, H., Mo, Q., et al. (2016) · Journal of Clinical Investigation · doi:10.1172/jci83476 · Cited by 174 · see citing works

CD28 Costimulation Is Essential for Human T Regulatory Expansion and Function

Golovina, T. N., Mikheeva, T., Suhoski, M. M., Aqui, N. A., Tai, V. C., Shan, X., Liu, R., Balcarcel, R. R., Fisher, N. C., Levine, B. L., et al. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.4.2855 · Cited by 162 · see citing works

Targeting ALDHbright Human Carcinoma–Initiating Cells with ALDH1A1-Specific CD8+ T Cells

Visús, C., Wang, Y., Lozano-León, A., Ferris, R. L., Silver, S., Szczepański, M. J., Brand, R. E., Ferrone, C. R., Whiteside, T. L., Ferrone, S., et al. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-1111 · Cited by 162 · see citing works

Chimeric Antigen Receptor T Cells: A Race to Revolutionize Cancer Therapy

Subklewe, M. S., von Bergwelt‐Baildon, M., & Humpe, A. (2019) · Transfusion Medicine and Hemotherapy · doi:10.1159/000496870 · Cited by 157 · see citing works

Antigen-specific activation and cytokine-facilitated expansion of naive, human CD8+ T cells

Wölfl, M., & Greenberg, P. D. (2014) · Nature Protocols · doi:10.1038/nprot.2014.064 · Cited by 154 · see citing works

The long road to the first FDA-approved gene therapy: chimeric antigen receptor T cells targeting CD19

Brændstrup, P., Levine, B. L., & Ruella, M. (2020) · Cytotherapy · doi:10.1016/j.jcyt.2019.12.004 · Cited by 153 · see citing works

TNF Activates a NF-κB–Regulated Cellular Program in Human CD45RA– Regulatory T Cells that Modulates Their Suppressive Function

Nagar, M., Jacob‐Hirsch, J., Vernitsky, H., Berkun, Y., Ben‐Horin, S., Amariglio, N., Bank, I., Kloog, Y., Rechavi, G., & Goldstein, I. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0902070 · Cited by 150 · see citing works

Steric Shielding of Surface Epitopes and Impaired Immune Recognition Induced by the Ebola Virus Glycoprotein

Francica, J. R., Varela‐Rohena, A., Medvec, A. R., Plesa, G., Riley, J. L., & Bates, P. F. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001098 · Cited by 146 · see citing works

Immunotherapy for Ovarian Cancer: What's Next?

Kandalaft, L. E., Powell, D. J., Singh, N., & Coukos, G. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.27.2369 · Cited by 148 · see citing works

Sleeping Beauty Transposon‐mediated Engineering of Human Primary T Cells for Therapy of CD19+ Lymphoid Malignancies

Huang, X., Guo, H., Kang, J., Choi, S., Zhou, T. C., Tammana, S., Lees, C. J., Li, Z.-Z., Milone, M. C., Levine, B. L., et al. (2008) · Molecular Therapy · doi:10.1038/sj.mt.6300404 · Cited by 146 · see citing works

Co-Stimulation through 4-1BB/CD137 Improves the Expansion and Function of CD8+ Melanoma Tumor-Infiltrating Lymphocytes for Adoptive T-Cell Therapy

Chacon, J. A., Wu, R. C. H., Sukhumalchandra, P., Molldrem, J. J., Sarnaik, A. A., Pilon‐Thomas, S., Weber, J. S., Hwu, P., & Radvanyi, L. G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060031 · Cited by 145 · see citing works

HIV integration site distributions in resting and activated CD4 + T cells infected in culture

Brady, T., Agosto, L. M., Malani, N., Berry, C. C., O’Doherty, U., & Bushman, F. D. (2009) · AIDS · doi:10.1097/qad.0b013e32832caf28 · Cited by 143 · see citing works

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

Hippen, K. L., Harker-Murray, P. D., Porter, S. B., Merkel, S. C., Londer, A., Taylor, D. K., Bina, M., Panoskaltsis‐Mortari, A., Rubinstein, P., van Rooijen, N., et al. (2008) · Blood · doi:10.1182/blood-2008-01-132951 · Cited by 143 · see citing works

A new approach to gene therapy using Sleeping Beauty to genetically modify clinical‐grade T cells to target CD 19

Singh, H., Huls, H. M., Kebriaei, P., & Cooper, L. J. N. (2013) · Immunological Reviews · doi:10.1111/imr.12137 · Cited by 137 · see citing works

NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation

Porter, D., Alyea, E. P., Antin, J. H., Lima, M. J. G. D., Estey, E. H., Falkenburg, J. H. F., Hardy, N. M., Kröger, N. M., Leis, J. F., Levine, J. E., et al. (2010) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2010.08.001 · Cited by 136 · see citing works

Activating and Propagating Polyclonal Gamma Delta T Cells with Broad Specificity for Malignancies

Deniger, D. C., Maiti, S. N., Mi, T., Switzer, K. C., Ramachandran, V., Hurton, L. V., Ang, S., Olivares, S., Rabinovich, B. A., Huls, M. H., et al. (2014) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-13-3451 · Cited by 132 · see citing works

Engineering lymph node homing of ex vivo–expanded human natural killer cells via trogocytosis of the chemokine receptor CCR7

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