Smith, Eric L.

GPRC5D-Targeted CAR T Cells for Myeloma

Mailankody, S., Devlin, S. M., Landa, J., Nath, K., Diamonte, C., Carstens, E. J., Russo, D., Auclair, R., Fitzgerald, L., Cadzin, B., et al. (2022) · New England Journal of Medicine

CAR-T cell therapy researchMultiple Myeloma Research and Treatments

Cited by 411

GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells

Smith, E. L., Harrington, K., Staehr, M., Masakayan, R., Jones, J., Long, T. J., Ng, K. Y., Ghoddusi, M., Purdon, T. J., Wang, X., et al. (2019) · Science Translational Medicine

CAR-T cell therapy researchMultiple Myeloma Research and Treatments

Cited by 391

Defining an Optimal Dual-Targeted CAR T-cell Therapy Approach Simultaneously Targeting BCMA and GPRC5D to Prevent BCMA Escape–Driven Relapse in Multiple Myeloma

Fernández de Larrea, C., Staehr, M., Lopez, A. V., Ng, K. Y., Chen, Y., Godfrey, W. D., Purdon, T. J., Ponomarev, V., Wendel, H.-G., Brentjens, R. J., et al. (2020) · Blood Cancer Discovery

CAR-T cell therapy researchMultiple Myeloma Research and Treatments

Cited by 223

The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases

Smith, E. L., & Schuchman, E. H. (2008) · The FASEB Journal

Sphingolipid Metabolism and SignalingLysosomal Storage Disorders Research

Cited by 213

Early-Life Stress and the Development of Obesity and Insulin Resistance in Juvenile Bonnet Macaques

Kaufman, D., Banerji, M. A., Shorman, I., Smith, E. L. P., Coplan, J. D., Rosenblum, L. A., & Kral, J. G. (2007) · Diabetes

Birth, Development, and HealthStress Responses and Cortisol

Cited by 138

Variable foraging demand rearing: sustained elevations in cisternal cerebrospinal fluid corticotropin-releasing factor concentrations in adult primates

Coplan, J. D., Smith, E. L. P., Altemus, M., Scharf, B. A., Owens, M. J., Nemeroff, C. B., Gorman, J. M., & Rosenblum, L. A. (2001) · Biological Psychiatry

Stress Responses and CortisolNeuroendocrine regulation and behavior

Cited by 129

Activation of Tumor-Cell STING Primes NK-Cell Therapy

Knelson, E. H., Ivanova, E. V., Tarannum, M., Campisi, M., Lizotte, P. H., Booker, M. A., Ozgenc, I., Noureddine, M., Meisenheimer, B., Chen, M., et al. (2022) · Cancer Immunology Research

interferon and immune responsesImmune Cell Function and Interaction

Cited by 88

Decreased choline and creatine concentrations in centrum semiovale in patients with generalized anxiety disorder: Relationship to IQ and early trauma

Coplan, J. D., Mathew, S. J., Mao, X., Smith, E. L. P., Hof, P. R., Coplan, P. M., Rosenblum, L. A., Gorman, J. M., & Shungu, D. C. (2006) · Psychiatry Research: Neuroimaging

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesAdvanced MRI Techniques and Applications

Cited by 45

Phase I First-in-Class Trial of MCARH109, a G Protein Coupled Receptor Class C Group 5 Member D (GPRC5D) Targeted CAR T Cell Therapy in Patients with Relapsed or Refractory Multiple Myeloma

Mailankody, S., Diamonte, C., Fitzgerald, L., Kane, P., Wang, X., Sikder, D. S., Senechal, B., Bermudez, V. P., Frias, D., Morgan, J., et al. (2021) · Blood

CAR-T cell therapy researchMultiple Myeloma Research and Treatments

Cited by 30