Julien, Jean-Pierre

Bone Marrow-Derived Microglia Play a Critical Role in Restricting Senile Plaque Formation in Alzheimer's Disease

Simard, A. R., Soulet, D., Gowing, G., Julien, J.-P., & Rivest, S. (2006) · Neuron

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 1,265

Axonal transport deficits and neurodegenerative diseases

Millecamps, S., & Julien, J.-P. (2013) · Nature Reviews Neuroscience

Hereditary Neurological DisordersAlzheimer's disease research and treatments

Cited by 755

Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

Urushitani, M., Sik, A., Sakurai, T., Nukina, N., Takahashi, R., & Julien, J.-P. (2006) · Nature Neuroscience

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 419

Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury

Patel, B. N., Dunn, R. J., Jeong, S. Y., Zhu, Q., Julien, J.-P., & David, S. (2002) · The Journal of Neuroscience

Neurological diseases and metabolismIron Metabolism and Disorders

Cited by 379

Exosome secretion is a key pathway for clearance of pathological TDP-43

Iguchi, Y., Eid, L., Parent, M., Soucy, G., Bareil, C., Riku, Y., Kawai, K., Takagi, S., Yoshida, M., Katsuno, M., et al. (2016) · Brain

Amyotrophic Lateral Sclerosis ResearchExtracellular vesicles in disease

Cited by 360

Extracellular mutant SOD1 induces microglial‐mediated motoneuron injury

Zhao, W., Beers, D. R., Henkel, J. S., Zhang, W., Urushitani, M., Julien, J., & Appel, S. H. (2010) · Glia

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 288

Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival

Saxena, S., Roselli, F., Singh, K., Leptien, K., Julien, J.-P., Gros-Louis, F., & Caroni, P. (2013) · Neuron

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 275

Exacerbation of Motor Neuron Disease by Chronic Stimulation of Innate Immunity in a Mouse Model of Amyotrophic Lateral Sclerosis

Nguyen, M. D., D'Aigle, T., Gowing, G., Julien, J.-P., & Rivest, S. (2004) · The Journal of Neuroscience

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 248

Inflammation Induces TDP-43 Mislocalization and Aggregation

Correia, A. S., Patel, P., Dutta, K., & Julien, J.-P. (2015) · PLOS ONE

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 114

Ubiquilin-2 drives NF-κB activity and cytosolic TDP-43 aggregation in neuronal cells

Picher-Martel, V., Dutta, K., Phaneuf, D., Sobue, G., & Julien, J.-P. (2015) · Molecular Brain

Amyotrophic Lateral Sclerosis ResearchNF-κB Signaling Pathways

Cited by 65

Protective effects of Withania somnifera extract in SOD1G93A mouse model of amyotrophic lateral sclerosis

Dutta, K., Patel, P., & Julien, J.-P. (2018) · Experimental Neurology

Amyotrophic Lateral Sclerosis ResearchPhytochemicals and Medicinal Plants

Cited by 56

Mitigation of ALS Pathology by Neuron-Specific Inhibition of Nuclear Factor Kappa B Signaling

Dutta, K., Thammisetty, S. S., Boutej, H., Bareil, C., & Julien, J.-P. (2020) · The Journal of Neuroscience

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 55

Macrophage colony stimulating factor (M-CSF) exacerbates ALS disease in a mouse model through altered responses of microglia expressing mutant superoxide dismutase

Gowing, G., Lalancette-Hébert, M., Audet, J.-N., Dequen, F., & Julien, J.-P. (2009) · Experimental Neurology

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 53