Braeuning, Albert

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P., Hewitt, N. J., Albrecht, U., Andersen, M. E., Ansari, N., Bhattacharya, S., Bode, J. G., Bolleyn, J., Borner, C., Böttger, J., et al. (2013) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 1,280

Adverse outcome pathways: opportunities, limitations and open questions

Leist, M., Ghallab, A., Graepel, R., Marchan, R., Hassan, R., Bennekou, S. H., Limonciel, A., Vinken, M., Schildknecht, S., Waldmann, T., et al. (2017) · Archives of Toxicology

Animal testing and alternativesAgricultural safety and regulations

Cited by 394

Differential gene expression in periportal and perivenous mouse hepatocytes

Braeuning, A., Ittrich, C., Köhle, C., Hailfinger, S., Bonin, M., Buchmann, A., & Schwarz, M. (2006) · The FEBS Journal

Liver physiology and pathologyPharmacogenetics and Drug Metabolism

Cited by 240

Activation of Human Nuclear Receptors by Perfluoroalkylated Substances (PFAS)

Behr, A.-C., Plinsch, C., Braeuning, A., & Buhrke, T. (2020) · Toxicology in Vitro

Per- and polyfluoroalkyl substances researchPeroxisome Proliferator-Activated Receptors

Cited by 235

T-cell factor 4 and β-catenin chromatin occupancies pattern zonal liver metabolism in mice

Gougelet, A., Torre, C., Veber, P., Sartor, C., Bachelot, L., Denechaud, P.-D., Godard, C., Moldes, M., Burnol, A.-F., Dubuquoy, C., et al. (2014) · Hepatology

Wnt/β-catenin signaling in development and cancerLiver physiology and pathology

Cited by 190

Cross-species analysis of hepatic cytochrome P450 and transport protein expression

Hammer, H., Schmidt, F., Marx-Stoelting, P., Pötz, O., & Braeuning, A. (2021) · Archives of Toxicology

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 104

Wnt/β-Catenin Signaling Activates and Determines Hepatic Zonal Expression of Glutathione S-Transferases in Mouse Liver

Giera, S., Braeuning, A., Köhle, C., Bursch, W., Metzger, U., Buchmann, A., & Schwarz, M. (2010) · Toxicological Sciences

Wnt/β-catenin signaling in development and cancerGlutathione Transferases and Polymorphisms

Cited by 66

Gender-Specific Interplay of Signaling through β-Catenin and CAR in the Regulation of Xenobiotic-Induced Hepatocyte Proliferation

Braeuning, A., Heubach, Y., Knorpp, T., Kowalik, M. A., Templin, M., Columbano, A., & Schwarz, M. (2011) · Toxicological Sciences

Wnt/β-catenin signaling in development and cancerLiver physiology and pathology

Cited by 40

The time point of β-catenin knockout in hepatocytes determines their response to xenobiotic activation of the constitutive androstane receptor

Ganzenberg, K., Singh, Y., & Braeuning, A. (2013) · Toxicology

Pharmacogenetics and Drug MetabolismWnt/β-catenin signaling in development and cancer

Cited by 29

Proteomic analysis of hepatic effects of phenobarbital in mice with humanized liver

Sprenger, H., Rasinger, J. D., Hammer, H., Naboulsi, W., Zabinsky, E., Planatscher, H., Schwarz, M., Poetz, O., & Braeuning, A. (2022) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionPharmacogenetics and Drug Metabolism

Cited by 12